Compare Lopressor vs. Losartan

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lopressor
(Metoprolol Tartrate)

Cozaar
(Losartan)

Lowers blood pressure and controls heart rate. Lopressor (Metoprolol Tartrate) is good for controlling chest pain and treating heart failure and heart attack. You have to take it with food, and you can't miss doses.Lowers blood pressure. Cozaar (Losartan) is a good blood pressure-lowering medicine that protects kidney function like an ACE inhibitor, but with fewer side effects.
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Reviews & ratings
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5.02Lopressor
Reviews for Lopressor (Metoprolol Tartrate)
62%
of people (All ages) say Lopressor (Metoprolol Tartrate) is worth it
47%
say it works well
15%
say it's a big hassle
464 reviews
Have you used Lopressor (Metoprolol Tartrate)?
Worth itNot sureNot worth it
Reviews for Cozaar (Losartan)
57%
5% vs. Lopressor (Metoprolol Tartrate)
48%
+1% vs. Lopressor (Metoprolol Tartrate)
16%
1% vs. Lopressor (Metoprolol Tartrate)
535 reviews
Have you used Cozaar (Losartan)?
Worth itNot sureNot worth it
Side effects
LopressorLosartan

The Lopressor FDA package insert doesn’t have numbers about how common side effects are.

More about Lopressor side effects »

The Losartan FDA package insert doesn’t have numbers about how common side effects are.

More about Losartan side effects »
How it works
LopressorLosartan
Lopressor (Metoprolol Tartrate) is a beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.Cozaar (Losartan) is an angiotensin receptor blocker (ARB). It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.
Type of medication
LopressorLosartan
Antihypertensive
Beta blocker
Prescription only
Antihypertensive
Angiotensin receptor blocker
Prescription only
Available as
LopressorLosartan
  • Pill
  • Pill
Used for (click to learn more)
LopressorLosartan
Risk factors for serious side effects
LopressorLosartan
  • Diabetes
  • Coronary artery disease
  • Heart failure
  • Major surgery requiring anesthesia
  • History of asthma
Detailed risks & warnings »
  • Women of childbearing age
  • Concurrent liver disease
  • Current kidney problems
  • Medicine that increase potassium
  • Use of salt substitute
Detailed risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Food
LopressorLosartan
  • Take it with food.
No food related info.
Kidneys and liver
LopressorLosartan
No kidneys and liver related info.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Requires routine blood tests to check kidney function.
Upsides and benefits
LopressorLosartan
  • A first-choice treatment to prevent chest pain (angina). Makes pain attacks less frequent and makes it easier to be active without having chest pain.
  • A first-choice treatment for heart failure. May prevent long-term heart damage.
  • A first-choice treatment for heart attack. Lowers the risk of death during and after a heart attack.
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Similar to ACE inhibitors (like Lisinopril), with fewer side effects like cough and swelling.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
Downsides and risks
LopressorLosartan
  • Metoprolol tartrate is the immediate release version of Toprol XL. You have to take Metoprolol tartrate with food for it to work best. (On the other hand, you can take Toprol XL any time.)
  • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
  • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
  • Can hide symptoms of low blood sugar if you're diabetic.
  • You can't miss doses. Stopping Metoprolol tartrate suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.
Tips from our pharmacists for people taking the medication
LopressorLosartan
  • Take it with food.
  • Can cause fatigue and headache.
  • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
  • Don't stop taking this medicine suddenly.
  • This is the immediate release version. It also comes as an extended release form: Toprol XL (metoprolol succinate).
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
  • Requires routine blood tests to check kidney function.
  • Don't take it if you're pregnant.
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
Learn more
More about LopressorSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Lopressor (Metoprolol Tartrate)?
Worth itNot sureNot worth it
More about LosartanSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Cozaar (Losartan)?
Worth itNot sureNot worth it