Compare Lopressor vs. Losartan

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lopressor
(metoprolol tartrate)

Cozaar
(losartan)

Lowers blood pressure and controls heart rate. Lopressor (metoprolol tartrate) lowers high blood pressure, controls chest pain, and helps treat heart failure and heart attack. You need to take it with food and can't miss a dose.Lowers blood pressure. Cozaar (Losartan) is a good blood pressure-lowering medicine that protects kidney function like an ACE inhibitor, but with fewer side effects.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.02Lopressor
Reviews for Lopressor
62%
of people (All ages) say Lopressor is worth it
47%
say it works well
15%
say it's a big hassle
464 reviews
Have you used Lopressor (metoprolol tartrate)?
Worth itNot sureNot worth it
Reviews for Losartan
57%
+5% better vs. Lopressor
48%
-1% worse vs. Lopressor
16%
+1% better vs. Lopressor
535 reviews
Have you used Cozaar (losartan)?
Worth itNot sureNot worth it
Side effects
LopressorLosartan
  • Tiredness 10%
  • Dizziness 10%
  • Depression 5%
  • Diarrhea 5%
  • Itching or skin rash 5%
  • Shortness of breath 3%
  • Slowed heart rate 3%
  • Low blood pressure 4%
More Lopressor side effects »
  • Upper respiratory infection 1%
  • Dizziness 1%
  • Back pain 1%
  • Nasal congestion 1%
  • Urinary tract infection 6%
  • Diarrhea 5%
  • Asthenia/Fatigue 4%
  • Anemia 3%
  • Hypoglycemia 4%
  • Back pain 2%
More Losartan side effects »
How it works
LopressorLosartan
Lopressor (metoprolol tartrate) is a beta blocker. It lowers blood pressure by slowing your heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.Cozaar (Losartan) is an angiotensin receptor blocker (ARB). It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.
Type of medication
LopressorLosartan
Prescription onlyPrescription only
Available as
LopressorLosartan
  • Pill
  • Pill
Used for
LopressorLosartan
Risk factors for serious side effects
LopressorLosartan
  • Suddenly stopping Lopressor (metoprolol tartrate)
  • Coronary artery disease
  • Diabetes
  • Heart failure
  • Major surgery requiring anesthesia
Detailed Lopressor (metoprolol tartrate) risks & warnings »
  • Women of childbearing age
  • Concurrent liver disease
  • Current kidney problems
  • Medicine that increase potassium
  • Use of salt substitute
Detailed Cozaar (losartan) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Food
LopressorLosartan
  • You need to take Lopressor (metoprolol tartrate) with food twice a day for it to work best.
No food related info.
Kidneys and liver
LopressorLosartan
No kidneys and liver related info.
  • Requires routine blood tests to check kidney function.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
Pain
LopressorLosartan
  • Makes pain episodes less frequent and makes it easier to be active without having chest pain.
No pain related info.
Upsides and benefits
LopressorLosartan
  • A first-choice treatment to prevent chest pain (angina).
  • Makes pain episodes less frequent and makes it easier to be active without having chest pain.
  • A first-choice treatment for people who've had a heart attack.
  • Lopressor (metoprolol tartrate) lowers the risk of death during and after a heart attack.
  • Lopressor (metoprolol tartrate) is cheaper than the extended release version.
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Similar to ACE inhibitors (like Lisinopril), with fewer side effects like cough and swelling.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
Downsides and risks
LopressorLosartan
  • You need to take Lopressor (metoprolol tartrate) with food twice a day for it to work best.
  • Taking Lopressor (metoprolol tartrate) may make you feel more tired or out of breath during exercise or your normal daily routines. This gets better for most people, but for some it may not go away.
  • Not a first-choice treatment for high blood pressure, unless you have heart failure or heart disease. It can also be added to other medicines if your blood pressure is still too high.
  • Can hide symptoms of low blood sugar if you're diabetic.
  • You can't miss doses. Stopping Lopressor (metoprolol tartrate) suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.
Tips from our pharmacists for people taking the medication
LopressorLosartan
  • You should take Lopressor (metoprolol tartrate) with or after meals.
  • Lopressor (metoprolol tartrate) can make you feel dizzy for the first few days. It can also cause fatigue and headaches.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
  • Don't stop taking this medicine suddenly unless your doctor tells you to.
  • This is the immediate release version of the medication, so it needs to be taken twice a day. It's different from the extended release form: Toprol XL (metoprolol succinate).
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
  • Requires routine blood tests to check kidney function.
  • Don't take it if you're pregnant.
Learn more
More about LopressorSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Lopressor (metoprolol tartrate)?
Worth itNot sureNot worth it
More about LosartanSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Cozaar (losartan)?
Worth itNot sureNot worth it