Compare Lopressor vs. Norvasc

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lopressor
(metoprolol tartrate)

Norvasc
(amlodipine)

Lowers blood pressure and controls heart rate. Lopressor (metoprolol tartrate) lowers high blood pressure, controls chest pain, and helps treat heart failure and heart attack. You need to take it with food and can't miss a dose.Lowers blood pressure. Norvasc (Amlodipine) works well to lower blood pressure and prevent chest pain. You can't miss doses, and you might get persistent swelling.
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Coupons for Norvasc
Best available price for 30 (5mg) tablets of amlodipine
Reviews & ratings
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Filter group. All currently selected
5.02Lopressor
Reviews for Lopressor (metoprolol tartrate)
62%
of people (All ages) say Lopressor (metoprolol tartrate) is worth it
47%
say it works well
15%
say it's a big hassle
464 reviews
Have you used Lopressor (metoprolol tartrate)?
Worth itNot sureNot worth it
Reviews for Norvasc (amlodipine)
58%
-4% worse vs. Lopressor (metoprolol tartrate)
50%
+3% better vs. Lopressor (metoprolol tartrate)
15%
Same vs. Lopressor (metoprolol tartrate)
443 reviews
Have you used Norvasc (amlodipine)?
Worth itNot sureNot worth it
Side effects
LopressorNorvasc
  • Tiredness 10%
  • Dizziness 10%
  • Low mood disorder 5%
  • Diarrhea 5%
  • Itching or skin rash 5%
  • Shortness of breath 3%
  • Slowed heart rate 3%
  • Low blood pressure 4%
More Lopressor side effects »
  • Swelling due to excess fluid 2%
  • Dizziness 1%
  • Heart pounding or racing sensation 5%
  • Flushing 3%
  • Fatigue 2%
  • Nausea 1%
  • Abdominal pain 2%
  • Drowsiness 2%
More Norvasc side effects »
How it works
LopressorNorvasc
Lopressor (metoprolol tartrate) is a beta blocker. It lowers blood pressure by slowing your heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.Norvasc (Amlodipine) is a calcium channel blocker. It lowers blood pressure by slowing your heart rate and relaxing your blood vessels. Your heart gets more oxygen and doesn't have to work as hard to pump, which can relieve chest pain.
Type of medication
LopressorNorvasc
Prescription only
Prescription only
Available as
LopressorNorvasc
  • Pill
  • Pill
Used for
LopressorNorvasc
Risk factors for serious side effects
LopressorNorvasc
  • Suddenly stopping Lopressor (metoprolol tartrate)
  • Coronary artery disease
  • Diabetes
  • Heart failure
  • Major surgery requiring anesthesia
Detailed Lopressor (metoprolol tartrate) risks & warnings »
  • Age 65 years or older
  • History of heart problems
  • Liver disease
  • History of blood vessel disease
  • History of heart failure
Detailed Norvasc (amlodipine) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Interactions
LopressorNorvasc
No interactions related info.
  • Interacts with the cholesterol medicine Simvastatin.
Food
LopressorNorvasc
  • You need to take Lopressor (metoprolol tartrate) with food twice a day for it to work best.
No food related info.
Kidneys and liver
LopressorNorvasc
No kidneys and liver related info.
  • Might not be a good choice if you have liver disease.
  • Your body uses your liver to break down Norvasc (Amlodipine) and remove it from your blood. If you have liver disease you may not be able to remove Norvasc (Amlodipine) as quickly from your blood as someone with a healthy liver. You should increase the dose of Norvasc (Amlodipine) slowly and watch closely for how it is working in your body. Increasing the dose slowly will lower your chances of having side effects.
Pain
LopressorNorvasc
  • Makes pain episodes less frequent and makes it easier to be active without having chest pain.
  • Worsening heart pain or increased risk of heart attack is possible when you first start taking Norvasc (Amlodipine). This can also happen after you increase the dose of Norvasc (Amlodipine). Notify your doctor immediately if you experience any heart pain, radiating jaw pain, crushing chest pain, or persistent racing heartbeat.
Upsides and benefits
LopressorNorvasc
  • A first-choice treatment to prevent chest pain (angina).
  • Makes pain episodes less frequent and makes it easier to be active without having chest pain.
  • A first-choice treatment for people who've had a heart attack.
  • Lopressor (metoprolol tartrate) lowers the risk of death during and after a heart attack.
  • Lopressor (metoprolol tartrate) is cheaper than the extended release version.
  • A first-choice blood pressure treatment for many people.
  • Calcium channel blockers work especially well for African Americans to lower blood pressure.
  • Lowers the risk of heart attack and stroke.
  • Prevents heart-related chest pain (angina) if you take it regularly.
  • Each dose lasts longer than other calcium channel blockers, which keeps blood pressure consistent without big ups and downs.
  • Particularly good at lowering systolic blood pressure (the top number), so it's a good option for older people who can commonly get high blood pressure only in the top number.
Downsides and risks
LopressorNorvasc
  • You need to take Lopressor (metoprolol tartrate) with food twice a day for it to work best.
  • Taking Lopressor (metoprolol tartrate) may make you feel more tired or out of breath during exercise or your normal daily routines. This gets better for most people, but for some it may not go away.
  • Not a first-choice treatment for high blood pressure, unless you have heart failure or heart disease. It can also be added to other medicines if your blood pressure is still too high.
  • Can hide symptoms of low blood sugar if you're diabetic.
  • You can't miss doses. Stopping Lopressor (metoprolol tartrate) suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • Calcium channel blockers can cause swelling in your limbs. If this happens for you, it probably won't get better over time, so talk to your doctor about alternatives if it bothers you.
  • Women are more likely to have side effects (especially swelling) from Amlodipine than men.
  • Some people might experience flushing with this medication.
  • You can't miss doses. Stopping Amlodipine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • If you have severe heart disease, using Amlodipine might increase your risk of chest pain or heart attack during the time right after starting the medication or raising the dosage.
  • Might not be a good choice if you have liver disease.
Tips from our pharmacists for people taking the medication
LopressorNorvasc
  • You should take Lopressor (metoprolol tartrate) with or after meals.
  • Lopressor (metoprolol tartrate) can make you feel dizzy for the first few days. It can also cause fatigue and headaches.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
  • Don't stop taking this medicine suddenly unless your doctor tells you to.
  • This is the immediate release version of the medication, so it needs to be taken twice a day. It's different from the extended release form: Toprol XL (metoprolol succinate).
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Interacts with the cholesterol medicine Simvastatin.
  • Can cause ankle or foot swelling.
  • Can cause gum overgrowth. Ask your dentist to check for this side effect.
Learn more
More about LopressorSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Lopressor (metoprolol tartrate)?
Worth itNot sureNot worth it
More about NorvascSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Norvasc (amlodipine)?
Worth itNot sureNot worth it