Compare Lopressor vs. Prazosin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lopressor
(Metoprolol Tartrate)

Minipress
(Prazosin)

Lowers blood pressure and controls heart rate. Lopressor (Metoprolol Tartrate) is good for controlling chest pain and treating heart failure and heart attack. You have to take it with food, and you can't miss doses.Lowers blood pressure and makes it easier to urinate. Prazosin is used mostly to make urination easier for men with an enlarged prostate, but it can cause dizziness.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
4.99103139013453Lopressor
Reviews for Lopressor (Metoprolol Tartrate)
61%
of people say Lopressor (Metoprolol Tartrate) is worth it
46%
say it works well
15%
say it's a big hassle
Reviews for Minipress (Prazosin)
43%
18% vs. Lopressor (Metoprolol Tartrate)
28%
18% vs. Lopressor (Metoprolol Tartrate)
15%
Same vs. Lopressor (Metoprolol Tartrate)
Side effects
LopressorPrazosin
  • Abnormally slow heartbeat 9%
  • Low blood pressure 4%
  • First-degree heart block 3%
More Lopressor side effects »

The Prazosin FDA package insert doesn’t have numbers about how common side effects are.

More about Prazosin side effects »
How it works
LopressorPrazosin
Lopressor (Metoprolol Tartrate) is a beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.Prazosin is a selective alpha blocker. It lowers blood pressure by relaxing blood vessels. It also relaxes the urethra and prostate, which makes it easier to urinate.
Type of medication
LopressorPrazosin
Antihypertensive
Beta blocker
Prescription only
Antihypertensive
Alpha blocker
Prescription only
Available as
LopressorPrazosin
  • Pill
  • Pill
Used for (click to learn more)
LopressorPrazosin
Risk factors for serious side effects
LopressorPrazosin
  • Diabetes
    • Coronary artery disease
    • Heart failure
    • Major surgery requiring anesthesia
    • History of asthma
    Detailed Lopressor (Metoprolol Tartrate) risks & warnings »
    • Age 65 years or older
    Detailed Minipress (Prazosin) risks & warnings »
    Pregnancy category
    LopressorPrazosin
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    Alcohol
    No specific alcohol-related info.No specific alcohol-related info.
    Food
    • Metoprolol tartrate is the immediate release version of Toprol XL. You have to take Metoprolol tartrate with food for it to work best. (On the other hand, you can take Toprol XL any time.)
    • Take it with food.
    • Take with food or at bedtime to avoid side effects.
    Kidneys and liver
    No specific kidneys and liver-related info.No specific kidneys and liver-related info.
    Sex
    No specific sex-related info.No specific sex-related info.
    Sleep
    No specific sleep-related info.
    • Helps people with PTSD get better sleep with fewer, less-intense nightmares.
    • Can cause drowsiness, headache, dizziness, and nausea.
    Weight
    No specific weight-related info.No specific weight-related info.
    Upsides and benefits
    LopressorPrazosin
    • A first-choice treatment to prevent chest pain (angina). Makes pain attacks less frequent and makes it easier to be active without having chest pain.
    • A first-choice treatment for heart failure. May prevent long-term heart damage.
    • A first-choice treatment for heart attack. Lowers the risk of death during and after a heart attack.
    • Can be added to other blood pressure-lowering medicines if you need additional blood pressure control.
    • Makes urination easier in men with an enlarged prostate.
    • Helps people with PTSD get better sleep with fewer, less-intense nightmares.
    Downsides and risks
    LopressorPrazosin
    • Metoprolol tartrate is the immediate release version of Toprol XL. You have to take Metoprolol tartrate with food for it to work best. (On the other hand, you can take Toprol XL any time.)
    • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
    • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
    • Can hide symptoms of low blood sugar if you're diabetic.
    • You can't miss doses. Stopping Metoprolol tartrate suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
    • Not the best medicine to lower blood pressure by itself.
    • Likely to cause orthostatic hypotension. This means dizziness when you change positions (like standing up) because your blood pressure doesn't adjust quickly enough.
    • Not preferred for people 65 years or older.
    Tips from our pharmacists for people taking the medication
    LopressorPrazosin
    • Take it with food.
    • Can cause dizziness in the first few days.
    • Can cause fatigue and headache.
    • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
    • Don't stop taking this medicine suddenly.
    • This is the immediate release version. It also comes as an extended release form: Toprol XL (metoprolol succinate).
    • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
    • Can cause drowsiness, headache, dizziness, and nausea.
    • Take with food or at bedtime to avoid side effects.
    • If side effects don't go away, talk to your doctor about alternatives.
    • Recheck your blood pressure 1 week after starting this medicine.
    • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
    Learn more
    More about LopressorSide effectsReviews & ratingsAlternativesFDA package insert
    More about PrazosinSide effectsReviews & ratingsAlternativesFDA package insert