Compare Lopressor vs. Prazosin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lopressor
(metoprolol tartrate)

Minipress
(prazosin)

Lowers blood pressure and controls heart rate. Lopressor (metoprolol tartrate) lowers high blood pressure, controls chest pain, and helps treat heart failure and heart attack. You need to take it with food and can't miss a dose.Lowers blood pressure and makes it easier to urinate. Prazosin is used mostly to make urination easier for men with an enlarged prostate, but it can cause dizziness.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.02Lopressor
Reviews for Lopressor
62%
of people (All ages) say Lopressor is worth it
47%
say it works well
15%
say it's a big hassle
464 reviews
Have you used Lopressor (metoprolol tartrate)?
Worth itNot sureNot worth it
Reviews for Prazosin
46%
+16% better vs. Lopressor
29%
+18% better vs. Lopressor
15%
Same vs. Lopressor
Have you used Minipress (prazosin)?
Worth itNot sureNot worth it
Side effects
LopressorPrazosin
  • Tiredness 10%
  • Dizziness 10%
  • Depression 5%
  • Diarrhea 5%
  • Itching or skin rash 5%
  • Shortness of breath 3%
  • Slowed heart rate 3%
  • Low blood pressure 4%
More Lopressor side effects »
  • Dizziness 10%
  • Headache 8%
  • Drowsiness 8%
  • Lack of energy 7%
  • Weakness 7%
  • Palpitations 5%
  • Nausea 5%
More Prazosin side effects »
How it works
LopressorPrazosin
Lopressor (metoprolol tartrate) is a beta blocker. It lowers blood pressure by slowing your heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.Prazosin is a selective alpha blocker. It lowers blood pressure by relaxing blood vessels. It also relaxes the urethra and prostate, which makes it easier to urinate.
Type of medication
LopressorPrazosin
Prescription onlyPrescription only
Available as
LopressorPrazosin
  • Pill
  • Pill
Used for
LopressorPrazosin
Risk factors for serious side effects
LopressorPrazosin
  • Suddenly stopping Lopressor (metoprolol tartrate)
  • Coronary artery disease
  • Diabetes
  • Heart failure
  • Major surgery requiring anesthesia
Detailed Lopressor (metoprolol tartrate) risks & warnings »
  • Age 65 years or older
Detailed Minipress (prazosin) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Food
LopressorPrazosin
  • You need to take Lopressor (metoprolol tartrate) with food twice a day for it to work best.
  • Take with food or at bedtime to avoid side effects.
Pain
LopressorPrazosin
  • Makes pain episodes less frequent and makes it easier to be active without having chest pain.
No pain related info.
Sleep
LopressorPrazosin
No sleep related info.
  • Can cause drowsiness, headache, dizziness, and nausea.
Upsides and benefits
LopressorPrazosin
  • A first-choice treatment to prevent chest pain (angina).
  • Makes pain episodes less frequent and makes it easier to be active without having chest pain.
  • A first-choice treatment for people who've had a heart attack.
  • Lopressor (metoprolol tartrate) lowers the risk of death during and after a heart attack.
  • Lopressor (metoprolol tartrate) is cheaper than the extended release version.
  • Can be added to other blood pressure-lowering medicines if you need additional blood pressure control.
  • Makes urination easier in men with an enlarged prostate.
  • Helps people with PTSD get better sleep with fewer, less-intense nightmares.
Downsides and risks
LopressorPrazosin
  • You need to take Lopressor (metoprolol tartrate) with food twice a day for it to work best.
  • Taking Lopressor (metoprolol tartrate) may make you feel more tired or out of breath during exercise or your normal daily routines. This gets better for most people, but for some it may not go away.
  • Not a first-choice treatment for high blood pressure, unless you have heart failure or heart disease. It can also be added to other medicines if your blood pressure is still too high.
  • Can hide symptoms of low blood sugar if you're diabetic.
  • You can't miss doses. Stopping Lopressor (metoprolol tartrate) suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • Not the best medicine to lower blood pressure by itself.
  • Likely to cause orthostatic hypotension. This means dizziness when you change positions (like standing up) because your blood pressure doesn't adjust quickly enough.
  • Not preferred for people 65 years or older.
Tips from our pharmacists for people taking the medication
LopressorPrazosin
  • You should take Lopressor (metoprolol tartrate) with or after meals.
  • Lopressor (metoprolol tartrate) can make you feel dizzy for the first few days. It can also cause fatigue and headaches.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
  • Don't stop taking this medicine suddenly unless your doctor tells you to.
  • This is the immediate release version of the medication, so it needs to be taken twice a day. It's different from the extended release form: Toprol XL (metoprolol succinate).
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Can cause drowsiness, headache, dizziness, and nausea.
  • Take with food or at bedtime to avoid side effects.
  • If side effects don't go away, talk to your doctor about alternatives.
  • Recheck your blood pressure 1 week after starting this medicine.
Learn more
More about LopressorSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Lopressor (metoprolol tartrate)?
Worth itNot sureNot worth it
More about PrazosinSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Minipress (prazosin)?
Worth itNot sureNot worth it