Compare Losartan vs. Avapro

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Cozaar (Losartan)

Prescription only

Avapro (irbesartan)

Prescription only
Lowers blood pressure.

Cozaar (Losartan) is a good blood pressure-lowering medicine that protects kidney function like an ACE inhibitor, but with fewer side effects.

3.7/ 5 average rating with 535 reviewsforLosartan
Lowers blood pressure.

Avapro (irbesartan) is a good blood pressure-lowering medicine that protects your kidneys and has few side effects.

Upsides
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Similar to ACE inhibitors (like Lisinopril), with fewer side effects like cough and swelling.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • Avapro (irbesartan) lowers your risk of heart attack and stroke.
  • It works similar to ACE inhibitors (like lisinopril), but it doesn't have the same side effects like coughing and facial swelling.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • It's recommended for people with heart failure since it lowers the risk of death and further damage to your heart.
  • Available in generic, and available with hydrochlorothiazide as a combination tablet.
Downsides
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.
  • You'll need to get yearly blood tests while taking Avapro (irbesartan) to see how it is affecting your body.
  • It's not safe to use Avapro (irbesartan) if you're pregnant.
  • Avapro (irbesartan) can cause the level of potassium in your blood to go up.
  • You'll need to get medical help if you notice any unusual swelling around your head and neck.
  • Can't be used in children under 18.
Used for
Dosage forms
  • Pill
  • Pill
Price
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Reviews
535 reviews so far
57%
saidit'sworth it
48%
saiditworked well
16%
saidit'sa big hassle

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Side effects
4possible side effects
  • Upper respiratory infection
    8%
  • Dizziness
    3%
  • Back pain
    2%
  • Nasal congestion
    2%
See more detailed side effects
The Avapro (irbesartan) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Harm to fetus
    • Women of childbearing age
  • Liver damage
    • Concurrent liver disease
  • Heart problems due to high potassium
    • Current kidney problems
    • Medicine that increase potassium
    • Use of salt substitute
See more detailed risks and warnings
  • Birth defects
    • Women of childbearing age
  • Worsening kidney problems
    • History of kidney problems
  • Swelling in the face and head
    • African descent
  • High potassium levels
    • Current kidney problems
    • Using medicines that increase potassium
    • Using salt substitutes
  • Lightheadedness & dizziness
    • Taking with alcohol
    • Taking other medicines that lower your blood pressure
    • Taking diurectics (water pills)
    • Dehydration
See more detailed risks and warnings