Compare Losartan vs. Benicar

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Cozaar
(Losartan)

Benicar
(Olmesartan)

Lowers blood pressure. Cozaar (Losartan) is a good blood pressure-lowering medicine that protects kidney function like an ACE inhibitor, but with fewer side effects.Lowers blood pressure. Benicar (Olmesartan) is a good blood pressure-lowering medicine that protects kidney function like an ACE inhibitor, but with fewer side effects.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.99Losartan
Reviews for Cozaar (Losartan)
57%
of people (All ages) say Cozaar (Losartan) is worth it
48%
say it works well
16%
say it's a big hassle
535 reviews
Have you used Cozaar (Losartan)?
Worth itNot sureNot worth it
Reviews for Benicar (Olmesartan)
65%
+8% better vs. Cozaar (Losartan)
63%
+15% better vs. Cozaar (Losartan)
12%
+4% better vs. Cozaar (Losartan)
118 reviews
Have you used Benicar (Olmesartan)?
Worth itNot sureNot worth it
Side effects
LosartanBenicar
  • Upper respiratory infection 1%
  • Dizziness 1%
  • Back pain 1%
  • Nasal congestion 1%
  • Urinary tract infection 6%
  • Diarrhea 5%
  • Muscle weakness/fatiguea/fatigue 4%
  • Low red blood cells 3%
  • Low blood sugar 4%
  • Back pain 2%
More Losartan side effects »
  • Dizziness 2%
More Benicar side effects »
How it works
LosartanBenicar
Cozaar (Losartan) is an angiotensin receptor blocker (ARB). It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Benicar (Olmesartan) is an angiotensin receptor blocker (ARB). It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.
Type of medication
LosartanBenicar
Prescription only
Prescription only
Available as
LosartanBenicar
  • Pill
  • Pill
Used for
LosartanBenicar
Risk factors for serious side effects
LosartanBenicar
  • Women of childbearing age
  • Concurrent liver disease
  • Current kidney problems
  • Medicine that increase potassium
  • Use of salt substitute
Detailed Cozaar (Losartan) risks & warnings »
    • African descent
    • Current kidney problems
    • Medicine that increase potassium
    • Use of salt substitute
      Detailed Benicar (Olmesartan) risks & warnings »
      Pregnancy

      Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Kidneys and liver
      LosartanBenicar
      • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
      • Requires routine blood tests to check kidney function.
      • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
      • Requires routine blood tests to check kidney function.
      Weight
      LosartanBenicar
      No weight related info.
      • Benicar (Olmesartan) has been reported to cause severe diarrhea and weight loss unexplained by other causes. Stay hydrated and notify your doctor if you continue to have more than 3-4 loose stools a day.
      Upsides and benefits
      LosartanBenicar
      • A first-choice blood pressure treatment for many people.
      • Lowers the risk of heart attack and stroke.
      • Similar to ACE inhibitors (like Lisinopril), with fewer side effects like cough and swelling.
      • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
      • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
      • A first-choice blood pressure treatment for many people.
      • Lowers the risk of heart attack and stroke.
      • Similar to ACE inhibitors (like Lisinopril), with fewer side effects like cough and swelling.
      • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
      • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
      Downsides and risks
      LosartanBenicar
      • Requires a yearly blood test to see how the medicine is affecting your body.
      • Not safe to use if you're pregnant.
      • Requires a yearly blood test to see how the medicine is affecting your body.
      • Not safe to use if you're pregnant.
      • Not available in less expensive generic form.
      Tips from our pharmacists for people taking the medication
      LosartanBenicar
      • Can cause dizziness in the first few days.
      • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
      • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
      • Requires routine blood tests to check kidney function.
      • Don't take it if you're pregnant.
      • Can cause dizziness in the first few days.
      • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
      • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
      • Requires routine blood tests to check kidney function.
      • Don't take it if you're pregnant.
      Learn more
      More about LosartanSide effectsReviews & ratingsAlternativesFDA package insert
      Have you used Cozaar (Losartan)?
      Worth itNot sureNot worth it
      More about BenicarSide effectsReviews & ratingsAlternativesFDA package insert
      Have you used Benicar (Olmesartan)?
      Worth itNot sureNot worth it