Compare Losartan vs. Coreg

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Cozaar
(Losartan)

Coreg
(Carvedilol)

Lowers blood pressure. Cozaar (Losartan) is a good blood pressure-lowering medicine that protects kidney function like an ACE inhibitor, but with fewer side effects.Lowers blood pressure and controls heart rate. Coreg (Carvedilol) is good for controlling chest pain and treating heart failure and heart attack. You have to take it with food, and you can't miss doses.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.99Losartan
Reviews for Cozaar (Losartan)
57%
of people (All ages) say Cozaar (Losartan) is worth it
48%
say it works well
16%
say it's a big hassle
535 reviews
Have you used Cozaar (Losartan)?
Worth itNot sureNot worth it
Reviews for Coreg (Carvedilol)
53%
-4% worse vs. Cozaar (Losartan)
46%
-2% worse vs. Cozaar (Losartan)
18%
-2% worse vs. Cozaar (Losartan)
406 reviews
Have you used Coreg (Carvedilol)?
Worth itNot sureNot worth it
Side effects
LosartanCoreg
  • Upper respiratory infection 1%
  • Dizziness 1%
  • Back pain 1%
  • Nasal congestion 1%
  • Urinary tract infection 6%
  • Diarrhea 5%
  • Muscle weakness/fatiguea/fatigue 4%
  • Low red blood cells 3%
  • Low blood sugar 4%
  • Back pain 2%
More Losartan side effects »
  • Dizziness 13%
  • Fatigue 2%
  • High blood sugar 4%
  • Diarrhea 6%
  • Weight increase 3%
  • Nausea 4%
  • Abnormally slow heartbeat 8%
  • Low blood pressure 6%
  • Headache 1%
More Coreg side effects »
How it works
LosartanCoreg
Cozaar (Losartan) is an angiotensin receptor blocker (ARB). It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Coreg (Carvedilol) is an alpha and beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.
Type of medication
LosartanCoreg
Prescription only
Prescription only
Available as
LosartanCoreg
  • Pill
  • Pill
  • Extended release
Used for
LosartanCoreg
Risk factors for serious side effects
LosartanCoreg
  • Women of childbearing age
  • Concurrent liver disease
  • Current kidney problems
  • Medicine that increase potassium
  • Use of salt substitute
Detailed Cozaar (Losartan) risks & warnings »
  • Abrupt discontinuation of Coreg (Carvedilol)
      • Congestive heart failure
      • Increasing the dose of Coreg (Carvedilol)
      • Diabetes
      • Major surgery requiring anesthesia
        Detailed Coreg (Carvedilol) risks & warnings »
        Pregnancy

        Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

        Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

        Food
        LosartanCoreg
        No food related info.
        • You have to take Carvedilol with food.
        • Take it with food.
        Kidneys and liver
        LosartanCoreg
        • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
        • Requires routine blood tests to check kidney function.
        No kidneys and liver related info.
        Upsides and benefits
        LosartanCoreg
        • A first-choice blood pressure treatment for many people.
        • Lowers the risk of heart attack and stroke.
        • Similar to ACE inhibitors (like Lisinopril), with fewer side effects like cough and swelling.
        • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
        • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
        • A first-choice treatment to prevent chest pain (angina).
        • A first-choice treatment for heart failure and heart attack.
        • For people with severe heart failure, Carvedilol lowers the risk of worsening heart failure, hospitalization, and sudden death.
        Downsides and risks
        LosartanCoreg
        • Requires a yearly blood test to see how the medicine is affecting your body.
        • Not safe to use if you're pregnant.
        • You have to take Carvedilol with food.
        • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
        • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
        • Can hide symptoms of low blood sugar if you're diabetic.
        • You can't miss doses. Stopping Carvedilol suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
        Tips from our pharmacists for people taking the medication
        LosartanCoreg
        • Can cause dizziness in the first few days.
        • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
        • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
        • Requires routine blood tests to check kidney function.
        • Don't take it if you're pregnant.
        • Take it with food.
        • Can cause dizziness in the first few days.
        • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
        • Can cause fatigue and erectile dysfunction.
        • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
        • Don't stop taking this medicine suddenly.
        Learn more
        More about LosartanSide effectsReviews & ratingsAlternativesFDA package insert
        Have you used Cozaar (Losartan)?
        Worth itNot sureNot worth it
        More about CoregSide effectsReviews & ratingsAlternativesFDA package insert
        Have you used Coreg (Carvedilol)?
        Worth itNot sureNot worth it