Lowers blood pressure. Cozaar (Losartan) is a good blood pressure-lowering medicine that protects kidney function like an ACE inhibitor, but with fewer side effects. Removes water from the body, which lowers blood pressure. Microzide (hydrochlorothiazide (HCTZ)) is a well-tolerated water pill that's often the first-choice treatment for mild high blood pressure. Reviews & ratings Everyone Men Women Filter group. All currently selected Everyone Men Women All ages 18-34 35-54 55+ Filter group. All currently selected All ages 18-34 35-54 55+ 4.99 Losartan
Reviews for Losartan
of people (All ages) say Losartan is worth it
say it works well
say it's a big hassle
Reviews for hydrochlorothiazide
+17% better vs. Losartan
Same vs. Losartan
Side effects Losartan hydrochlorothiazide
Upper respiratory infection 1%
Back pain 1%
Nasal congestion 1%
Urinary tract infection 6%
Muscle weakness/fatiguea/fatigue 4%
Low red blood cells 3%
Low blood sugar 4%
Back pain 2%
More Losartan side effects »
The hydrochlorothiazide FDA package insert doesn’t have numbers about how common side effects are.
More about hydrochlorothiazide side effects » How it works Losartan hydrochlorothiazide Cozaar (Losartan) is an angiotensin receptor blocker (ARB). It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs. Microzide (hydrochlorothiazide (HCTZ)) is a thiazide diuretic (water pill) that makes you urinate more. It works in the kidneys to remove extra water and certain electrolytes, while lowering blood pressure and reducing swelling. Type of medication Losartan hydrochlorothiazide Prescription only Prescription only Available as Losartan hydrochlorothiazide Used for Losartan hydrochlorothiazide Risk factors for serious side effects Losartan hydrochlorothiazide › Women of childbearing age › Concurrent liver disease › Current kidney problems › Medicine that increase potassium › Use of salt substitute Detailed Cozaar (losartan) risks & warnings » › Current electrolyte imbalance › Lower kidney function › Dehydration › History of sulfa allergies › History of gout Detailed Microzide (hydrochlorothiazide ) risks & warnings »
Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.
Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.
Kidneys and liver Losartan hydrochlorothiazide › Requires routine blood tests to check kidney function. › Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease. › Requires routine blood tests to check kidney function. Upsides and benefits Losartan hydrochlorothiazide › A first-choice blood pressure treatment for many people. › Lowers the risk of heart attack and stroke. › Similar to ACE inhibitors (like Lisinopril), with fewer side effects like cough and swelling. › Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease. › Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart. › Does a good job getting rid of extra fluids in your body by making you urinate more. › A first-choice blood pressure treatment. Works especially well for people of African descent. › Lowers the risk of heart attack and stroke. › Good option if you have high blood pressure and heart failure. › Most people have very few side effects from Microzide (hydrochlorothiazide (HCTZ)). › Can be good for patients with osteoporosis since it raises the body's level of calcium. Downsides and risks Losartan hydrochlorothiazide › Requires a yearly blood test to see how the medicine is affecting your body. › Not safe to use if you're pregnant. › Makes you urinate more often. › Microzide (hydrochlorothiazide (HCTZ)) doesn't work well in people with severe kidney problems. › It can increase the risk of gout attacks in people with poor kidney function or a history of gout. › People with a sulfa allergy may be allergic to Microzide (hydrochlorothiazide (HCTZ)). Tips from our pharmacists for people taking the medication Losartan hydrochlorothiazide › Can cause dizziness in the first few days. › Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved. › Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away. › Requires routine blood tests to check kidney function. › Don't take it if you're pregnant. › Microzide (hydrochlorothiazide (HCTZ)) starts working in about 2 hours. › It makes you urinate more often, so don't take it at bedtime. › Can cause dizziness in the first few days. › Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved. › Tell your doctor about any tiredness or muscle weakness that doesn't go away. › Requires routine blood tests to check kidney function. Learn more More about Losartan Side effects Reviews & ratings Alternatives FDA package insert More about hydrochlorothiazide Side effects Reviews & ratings Alternatives FDA package insert