Compare Losartan vs. Nifedipine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Cozaar (Losartan)

Prescription only

Procardia (Nifedipine)

Prescription only
Lowers blood pressure.

Cozaar (Losartan) is a good blood pressure-lowering medicine that protects kidney function like an ACE inhibitor, but with fewer side effects.

3.7/ 5 average rating with 535 reviewsforLosartan
Lowers blood pressure and controls heart rate.

Nifedipine works well to lower blood pressure and prevent chest pain, but you have to be okay with avoiding grapefruit. You can't miss doses, and you might get persistent swelling.

2.8/ 5 average rating with 26 reviewsforNifedipine
Upsides
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Similar to ACE inhibitors (like Lisinopril), with fewer side effects like cough and swelling.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • A first-choice blood pressure treatment for many people.
  • Calcium channel blockers work especially well for African Americans to lower blood pressure.
  • You can take it alone or with other medicines to help lower blood pressure.
  • Lowers the risk of heart attack and stroke.
  • Prevents heart-related chest pain (angina) if you take it regularly.
  • Treats certain abnormal heart rhythms.
Downsides
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.
  • Calcium channel blockers can cause swelling in your limbs. If this happens for you, it probably won't get better over time, so talk to your doctor about alternatives if it bothers you.
  • Women are more likely to have side effects (especially swelling) from Nifedipine than men.
  • You can't miss doses. Stopping Nifedipine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • Not a good medication for you if you love grapefruit. It can make Nifedipine have a stronger effect on your blood pressure.
Used for
Dosage forms
  • Pill
  • Pill
  • Extended release
Price
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Reviews
535 reviews so far
57%
saidit'sworth it
48%
saiditworked well
16%
saidit'sa big hassle

Have you used Cozaar (Losartan)?

Leave a review
26 reviews so far
42%
saidit'sworth it
31%
saiditworked well
46%
saidit'sa big hassle

Have you used Procardia (Nifedipine)?

Leave a review
Side effects
4possible side effects
  • Upper respiratory infection
    8%
  • Dizziness
    3%
  • Back pain
    2%
  • Nasal congestion
    2%
See more detailed side effects
11possible side effects
  • Dizziness, lightheadedness, giddiness
    27%
  • Flushing
    25%
  • Headache
    23%
  • Weakness
    12%
  • Nausea, heartburn
    11%
  • Muscle cramps, tremor
    8%
  • Peripheral edema
    7%
  • Nervousness, mood changes
    7%
  • Palpitation
    7%
  • Dyspnea, cough, wheezing
    6%
  • Nasal congestion, sore throat
    6%
See more detailed side effects
Risks and risk factors
  • Harm to fetus
    • Women of childbearing age
  • Liver damage
    • Concurrent liver disease
  • Heart problems due to high potassium
    • Current kidney problems
    • Medicine that increase potassium
    • Use of salt substitute
See more detailed risks and warnings
  • Intestinal blockage
    • Taking anti-inflammatories, acid reducers in the stomach, anticholinergics, laxatives, levothyroxine
    • History of intestinal surgery
  • Chest pain
    • Taking beta-blockers
    • Severe coronary artery disease.
  • Liver damage/jaundice
    • History of cirrhosis
  • Low blood pressure
  • Congestive heart failure
    • History of tight aortic stenosis
    • Taking beta-blockers
  • Heart attack or increased chest pain
    • Obstructive coronary artery disease
See more detailed risks and warnings