Compare Lovastatin vs. Niaspan

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Mevacor (Lovastatin)

Prescription only

Niaspan (Niacin)

Prescription only
Lowers cholesterol.

Mevacor (Lovastatin) can improve cholesterol, but it's not as strong as other statin medicines. Statin side effects can be difficult to deal with, but the benefits might outweigh the risks.

3.4/ 5 average rating with 89 reviewsforLovastatin
Lowers cholesterol.

Niaspan (Niacin) lowers triglycerides, but isn't as good as statins for improving cholesterol levels.

3.2/ 5 average rating with 380 reviewsforNiaspan
Upsides
  • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Can lower the risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
  • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Good for lowering triglycerides (fats).
Downsides
  • Not the best choice for people who have very high cholesterol levels.
  • Statins can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, and liver damage. Some people have to stop taking this medicine because of these problems.
  • You're at higher risk for these side effects if you are female, are 65 years or older, drink alcohol every day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
  • Not safe to use if you're pregnant.
  • By itself, Niaspan (Niacin) isn't as effective as statins for improving cholesterol levels.
  • It can cause flushing and stomach pain or discomfort.
  • You need to take it before bedtime with a low-fat snack.
  • If you miss doses often, you may need to re-start taking the medicine more regularly at a lower dose.
Used for
Dosage forms
  • Pill
  • Extended release
  • Pill
  • Extended release
Price
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Reviews
89 reviews so far
43%
saidit'sworth it
39%
saiditworked well
22%
saidit'sa big hassle

Have you used Mevacor (Lovastatin)?

Leave a review
380 reviews so far
43%
saidit'sworth it
31%
saiditworked well
19%
saidit'sa big hassle

Have you used Niaspan (Niacin)?

Leave a review
Side effects
2possible side effects
  • Elevations of CK levels
    11%
  • Increase in serum transaminases
    2%
See more detailed side effects
6possible side effects
  • Flushing
    68%
  • Itching
    8%
  • Diarrhea
    7%
  • Nausea
    5%
  • Rash
    5%
  • Cough increased
    3%
See more detailed side effects
Risks and risk factors
  • Muscle pain
    • Kidney disease
    • High dose of Mevacor (Lovastatin)
    • Combining with certain cholesterol-lowering drugs
    • Older age and female gender
  • Liver damage
    • Heavy alcohol use
    • History of chronic liver disease
  • Harm to fetus
    • Pregnancy
    • Breast feeding
  • Drug interactions
    • Taking with certain drugs that increase the dose of Mevacor (Lovastatin) in the body
  • Muscle weakness (autoimmune)
See more detailed risks and warnings
  • Muscle pain
    • Taking Niaspan (Niacin) with statins
  • Liver damage
    • Heavy alcohol use
    • Past history of liver disease
  • High blood sugar
    • Diabetes
  • Low platelets
    • Taking Niaspan (Niacin) with anticoagulants
  • Gout
    • Gout
See more detailed risks and warnings