Compare Lovastatin vs. pravastatin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Mevacor
(lovastatin)

Pravachol
(pravastatin)

Lowers cholesterol. Mevacor (Lovastatin) can improve cholesterol, but it's not as strong as other statin medicines. Statin side effects can be difficult to deal with, but the benefits might outweigh the risks.Lowers cholesterol. Pravachol (pravastatin) can improve cholesterol, but it's not as strong as other statin medicines. It does cause fewer side effects and is safer for your kidneys and liver.
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Coupons for Lovastatin
Best available price for 30 (20mg) tablets of lovastatin
Coupons for pravastatin
Best available price for 30 (40mg) tablets of pravastatin
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.54Lovastatin
Reviews for Lovastatin
43%
of people (All ages) say Lovastatin is worth it
39%
say it works well
22%
say it's a big hassle
Have you used Mevacor (lovastatin)?
Worth itNot sureNot worth it
Reviews for pravastatin
54%
-11% worse vs. Lovastatin
44%
-5% worse vs. Lovastatin
19%
-3% worse vs. Lovastatin
426 reviews
Have you used Pravachol (pravastatin)?
Worth itNot sureNot worth it
Side effects
Lovastatinpravastatin
  • Diarrhea 1%
  • Muscle pain 1%
  • Muscle weakness 1%
  • Elevations of ck levels 11%
More Lovastatin side effects »
  • Upper respiratory infection 4%
  • Diarrhea 3%
  • Headache 2%
  • Chest pain 2%
  • Sore throat 2%
  • Rash 2%
  • Muscle pain 2%
More pravastatin side effects »
How it works
Lovastatinpravastatin
Mevacor (Lovastatin) is cholesterol-lowering medicine called a statin. It lowers the amount of cholesterol your body makes, which helps lower "bad" cholesterol (LDL) and raise "good" cholesterol (HDL).Pravachol (pravastatin) is cholesterol-lowering medicine called a statin. It lowers the amount of cholesterol your body makes, which helps lower "bad" cholesterol (LDL) and raise "good" cholesterol (HDL).
Type of medication
Lovastatinpravastatin
Prescription onlyPrescription only
Available as
Lovastatinpravastatin
  • Pill
  • Extended release
  • Pill
Used for
Lovastatinpravastatin
Risk factors for serious side effects
Lovastatinpravastatin
  • Kidney disease
  • High dose of Mevacor (Lovastatin)
  • Combining with certain cholesterol-lowering drugs
  • Older age and female gender
  • Heavy alcohol use
Detailed Mevacor (lovastatin) risks & warnings »
  • Kidney disease
  • An underactive thyroid
  • Over age 65
  • Female gender
  • Taking other medicines to lower your cholesterol
Detailed Pravachol (pravastatin) risks & warnings »
Pregnancy

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

Interactions
Lovastatinpravastatin
  • Certain medications can interact with this drug. Talk to your doctor or pharmacist.
No interactions related info.
Alcohol
Lovastatinpravastatin
  • You're at higher risk for these side effects if you are female, are 65 years or older, drink alcohol every day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
No alcohol related info.
Food
Lovastatinpravastatin
  • Works best if you take it once a day after your evening meal.
No food related info.
Kidneys and liver
Lovastatinpravastatin
  • There are rare cases of muscle damage leading to kidney failure in people taking Mevacor (Lovastatin). The risk is greater in people with kidney disease or thyroid disease, are older and female and taking certain cholesterol-lowering medication combinations. Tell your doctor if you develop sudden muscle pain, weakness or fever and there is no known cause.
  • There are reports of liver damage in people who take Mevacor (Lovastatin), especially if they are heavy alcohol drinkers or have a history of liver disease. If you notice dark urine or yellowing of the eyes or skin, tell your doctor. Your doctor may also want to check your liver function periodically.
  • Statins can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, and liver damage. Some people have to stop taking this medicine because of these problems.
  • Pravachol (pravastatin) is less likely to cause muscle and kidney damage than other statin medicines.
  • If you have liver problems, Pravachol (pravastatin) is the safest statin to use.
Pain
Lovastatinpravastatin
  • Combining certain medications can increase the risk of muscle pain (myopathy), muscle damage (rhabdomyolysis) and kidney damage. Talk to your doctor or pharmacist when taking any new medications.
No pain related info.
Upsides and benefits
Lovastatinpravastatin
  • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Can lower the risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
  • Compared to other statins, Pravachol (pravastatin) has fewer interactions with medicines.
  • Pravachol (pravastatin) is less likely to cause muscle and kidney damage than other statin medicines.
  • If you have liver problems, Pravachol (pravastatin) is the safest statin to use.
  • It's available as a generic.
Downsides and risks
Lovastatinpravastatin
  • Not the best choice for people who have very high cholesterol levels.
  • Statins can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, and liver damage. Some people have to stop taking this medicine because of these problems.
  • You're at higher risk for these side effects if you are female, are 65 years or older, drink alcohol every day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
  • Not safe to use if you're pregnant.
  • Pravachol (pravastatin) isn't as strong as other statins in lowering your cholesterol.
  • You'll still need to eat a low fat diet and exercise regularly to get the full benefit of Pravachol (pravastatin).
Tips from our pharmacists for people taking the medication
Lovastatinpravastatin
  • Lowers bad cholesterol and triglycerides, and raises good cholesterol.
  • Most people reach their target cholesterol levels in 4 to 6 weeks.
  • Works best if you take it once a day after your evening meal.
  • Avoid grapefruit and grapefruit juice while taking this medicine.
  • Tell your doctor if you develop sudden muscle pain, fever, or weakness.
  • Tell your doctor if you notice dark urine or yellowing of the eyes or skin.
  • Certain medications can interact with this drug. Talk to your doctor or pharmacist.
  • Lowers bad cholesterol and triglycerides, and raises good cholesterol.
  • Most people reach their target cholesterol levels in 4 to 6 weeks.
  • Don't eat grapefruit and drink grapefruit juice while taking this medicine.
  • Tell your doctor if you develop sudden muscle pain, fever, or weakness.
  • Also let your doctor know if you notice dark urine or yellowing of your eyes or skin.
  • You'll need to stop taking Pravachol (pravastatin) if you get pregnant.
Learn more
More about LovastatinSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Mevacor (lovastatin)?
Worth itNot sureNot worth it
More about pravastatinSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Pravachol (pravastatin)?
Worth itNot sureNot worth it