Compare Lovastatin vs. Trilipix

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Mevacor
(lovastatin)

Trilipix
(fenofibric acid)

Lowers cholesterol. Mevacor (Lovastatin) can improve cholesterol, but it's not as strong as other statin medicines. Statin side effects can be difficult to deal with, but the benefits might outweigh the risks.Lowers cholesterol. Trilipix is good for lowering triglycerides (fats), but it's not as good as statins for improving cholesterol and cardiovascular disease risk.
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Prices and coupon for 30 (40mg) tablets of lovastatin
Coupons for
Prices and coupon for 30 (105mg) tablets of fenofibric acid
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.54Lovastatin
Reviews for Mevacor (lovastatin)
43%
of people (All ages) say Mevacor (lovastatin) is worth it
39%
say it works well
22%
say it's a big hassle
Have you used Mevacor (lovastatin)?
Worth itNot sureNot worth it
Reviews for Trilipix (fenofibric acid)
50%
+7% better vs. Mevacor (lovastatin)
22%
-17% worse vs. Mevacor (lovastatin)
25%
-3% worse vs. Mevacor (lovastatin)
Have you used Trilipix (fenofibric acid)?
Worth itNot sureNot worth it
Side effects
LovastatinTrilipix
  • Diarrhea 1%
  • Muscle pain 1%
  • Muscle weakness 1%
  • Elevations of ck levels 11%
More Lovastatin side effects »
  • Headache 13%
  • Back pain 6%
  • Pain in extremity 5%
  • Ear, nose, or throat infection 5%
  • Nausea 4%
  • Common cold 4%
  • Diarrhea 4%
  • Joint pain 4%
  • Pain 4%
  • Dizziness 4%
More Trilipix side effects »
How it works
LovastatinTrilipix
Mevacor (Lovastatin) is cholesterol-lowering medicine called a statin. It lowers the amount of cholesterol your body makes, which helps lower "bad" cholesterol (LDL) and raise "good" cholesterol (HDL).Trilipix is a cholesterol-lowering medicine. It removes triglycerides from your body and makes it easier to process "bad" cholesterol (LDL). This also increases "good" cholesterol (HDL).
Type of medication
LovastatinTrilipix
Prescription only
Prescription only
Available as
LovastatinTrilipix
  • Pill
  • Extended release
  • Pill
  • Extended release
Used for
LovastatinTrilipix
Risk factors for serious side effects
LovastatinTrilipix
  • Kidney disease
  • High dose of Mevacor (Lovastatin)
  • Combining with certain cholesterol-lowering drugs
  • Older age and female gender
  • Heavy alcohol use
  • History of chronic liver disease
  • Pregnancy
  • Breast feeding
  • Taking with certain drugs that increase the dose of Mevacor (Lovastatin) in the body
    Detailed Mevacor (lovastatin) risks & warnings »
    • Taking Trilipix (Fenofibric Acid) with statins
    • Past history of liver disease
      • Taking Trilipix (Fenofibric Acid) with anticoagulants
                Detailed Trilipix (fenofibric acid) risks & warnings »
                Pregnancy

                Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

                Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                Interactions
                LovastatinTrilipix
                • Certain medications can interact with this drug. Talk to your doctor or pharmacist.
                No interactions related info.
                Alcohol
                LovastatinTrilipix
                • You're at higher risk for these side effects if you are female, are 65 years or older, drink alcohol every day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
                No alcohol related info.
                Food
                LovastatinTrilipix
                • Works best if you take it once a day after your evening meal.
                No food related info.
                Kidneys and liver
                LovastatinTrilipix
                • Statins can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, and liver damage. Some people have to stop taking this medicine because of these problems.
                • There are rare cases of muscle damage leading to kidney failure in people taking Mevacor (Lovastatin). The risk is greater in people with kidney disease or thyroid disease, are older and female and taking certain cholesterol-lowering medication combinations. Tell your doctor if you develop sudden muscle pain, weakness or fever and there is no known cause.
                • There are reports of liver damage in people who take Mevacor (Lovastatin), especially if they are heavy alcohol drinkers or have a history of liver disease. If you notice dark urine or yellowing of the eyes or skin, tell your doctor. Your doctor may also want to check your liver function periodically.
                • Reports of liver damage have been reported in people who take Trilipix (Fenofibric Acid), especially in people with a history of liver disease. Your doctor may monitor your liver with blood tests on a regular basis.
                Pain
                LovastatinTrilipix
                • Combining certain medications can increase the risk of muscle pain (myopathy), muscle damage (rhabdomyolysis) and kidney damage. Talk to your doctor or pharmacist when taking any new medications.
                No pain related info.
                Upsides and benefits
                LovastatinTrilipix
                • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
                • Can lower the risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
                • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
                • Good medicine for lowering triglycerides.
                Downsides and risks
                LovastatinTrilipix
                • Not the best choice for people who have very high cholesterol levels.
                • Statins can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, and liver damage. Some people have to stop taking this medicine because of these problems.
                • You're at higher risk for these side effects if you are female, are 65 years or older, drink alcohol every day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
                • Not safe to use if you're pregnant.
                • In clinical studies, Trilipix hasn't lowered cholesterol or the risk of heart attack and stroke better than statins.
                • Different forms and strengths of this medication can't be substituted for each other.
                Tips from our pharmacists for people taking the medication
                LovastatinTrilipix
                • Lowers bad cholesterol and triglycerides, and raises good cholesterol.
                • Most people reach their target cholesterol levels in 4 to 6 weeks.
                • Works best if you take it once a day after your evening meal.
                • Avoid grapefruit and grapefruit juice while taking this medicine.
                • Tell your doctor if you develop sudden muscle pain, fever, or weakness.
                • Tell your doctor if you notice dark urine or yellowing of the eyes or skin.
                • Certain medications can interact with this drug. Talk to your doctor or pharmacist.
                • Can be used with other medications to help lower cholesterol.
                • Lowers triglycerides.
                • Can raise your chance of getting colds and flu.
                • Call your doctor if you develop muscle or abdominal pain.
                • Also taking Welchol or Questran? Take this medicine at least 2 hours before or 4 hours after.
                Learn more
                More about LovastatinSide effectsReviews & ratingsAlternativesFDA package insert
                Have you used Mevacor (lovastatin)?
                Worth itNot sureNot worth it
                More about TrilipixSide effectsReviews & ratingsAlternativesFDA package insert
                Have you used Trilipix (fenofibric acid)?
                Worth itNot sureNot worth it