Compare Lovenox vs. Arixtra

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lovenox
(Enoxaparin)

Arixtra
(Fondaparinux)

Prevents blood clots. Lovenox (Enoxaparin) is a good anticoagulant that reduces the risk of death or bleeding, and blood clots are less likely to happen. However, it is only available as an injection which isn't great if you're afraid of needles.Coming soon.
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Reviews & ratings
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Side effects
LovenoxArixtra
  • Injection site hematoma 7%
  • Fever 2%
  • Confusion 1%
  • Nausea 1%
More Lovenox side effects »

We haven’t found good data for Arixtra side effects.

FDA side effect reports for Arixtra »
How it works
LovenoxArixtra
Lovenox (Enoxaparin) is an anticoagulant that prevents certain blood-clotting proteins from working. By stopping blood clots from forming, there's a lower chance of having a stroke or blood clots travel to your lungs.Coming soon.
Type of medication
LovenoxArixtra
Anticoagulant
Heparin
Prescription only
Coming soon.
Available as
LovenoxArixtra
  • Injection
  • Injection
Used for (click to learn more)
LovenoxArixtra
  • Deep venous thrombosis
Risk factors for serious side effects
LovenoxArixtra
  • Spinal puncture (spinal tap)
  • Getting anesthesia in the spine (epidural anesthesia)
  • Taking NSAIDs or other blood thinning medicines
  • History of bleeding problems
  • Severe high blood pressure
  • Older age
  • Stopping Lovenox (Enoxaparin) early
  • Heparin-induced thrombocytopenia
Detailed Lovenox (Enoxaparin) risks & warnings »
Coming soon.
Pregnancy category
LovenoxArixtra
BFDA pregnancy category (Probably safe)

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

See the FDA package insert
BFDA pregnancy category (Probably safe)

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

See the FDA package insert
Alcohol
No specific alcohol-related info.No specific alcohol-related info.
Food
No specific food-related info.No specific food-related info.
Kidneys and liver
  • It doesn't work as well as other medications for "thinning the blood" if you are overweight, underweight, or if you have kidney disease.
No specific kidneys and liver-related info.
Sex
No specific sex-related info.No specific sex-related info.
Sleep
No specific sleep-related info.No specific sleep-related info.
Weight
No specific weight-related info.No specific weight-related info.
Upsides and benefits
LovenoxArixtra
  • In a study that compared Lovenox (Enoxaparin) to other medications used to stop blood clots, there was a lower risk of clots coming back, with similar rates of major bleeding and mortality.
  • You don't need to go in for lab tests to check whether it's working, unlike other medications like warfarin that require regular blood draws.
  • Available in generic so it can be cheaper than other "blood thinners".
  • Good option if you're pregnant or have cancer.
Coming soon.
Downsides and risks
LovenoxArixtra
  • It is only available as an injection, so it's not great if you're afraid of needles.
  • While surprise bleeding episodes can be treated while taking Lovenox (Enoxaparin), they won't completely work.
  • It doesn't work as well as other medications for "thinning the blood" if you are overweight, underweight, or if you have kidney disease.
Coming soon.
Tips from our pharmacists for people taking the medication
LovenoxArixtra
  • Rotate the spot where you inject Lovenox (Enoxaparin) every day.
  • While on this, it can take longer to stop bleeding and you are more likely to bruise or bleed more easily.
  • Avoid taking certain anti-inflammatory drugs (like NSAIDs) because they can make you more likely to bleed.
  • Can cause swelling in your legs, diarrhea, and nausea.
Coming soon.
Learn more
More about LovenoxSide effectsReviews & ratingsAlternativesFDA package insert
More about ArixtraSide effectsFDA package insert