Compare Lovenox vs. Eliquis

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lovenox (Enoxaparin)

Prescription only

Eliquis (apixaban)

Prescription only
Prevents blood clots.

Lovenox (Enoxaparin) is a good anticoagulant that reduces the risk of death or bleeding, and blood clots are less likely to happen. However, it is only available as an injection which isn't great if you're afraid of needles.

4.0/ 5 average rating with 19 reviewsforLovenox
Prevents blood clots.

Eliquis (apixaban) is an effective way to prevent blood clots from forming in your veins, but you have to take it twice a day, and your doctor might have to change the dose a lot.

3.8/ 5 average rating with 19 reviewsforEliquis
Upsides
  • In a study that compared Lovenox (Enoxaparin) to other medications used to stop blood clots, there was a lower risk of clots coming back, with similar rates of major bleeding and mortality.
  • You don't need to go in for lab tests to check whether it's working, unlike other medications like warfarin that require regular blood draws.
  • Available in generic so it can be cheaper than other "blood thinners".
  • Good option if you're pregnant or have cancer.
  • Eliquis (apixaban) is very effective in reducing the risk of stroke in people with atrial fibrilation or other clotting disorders.
  • You don't need to have regular blood tests on Eliquis (apixaban), and you don't have to regulate your diet like other blood thinners.
  • If you've had clots in your legs or lungs before, Eliquis (apixaban) can lower the risk of these forming again.
Downsides
  • It is only available as an injection, so it's not great if you're afraid of needles.
  • While surprise bleeding episodes can be treated while taking Lovenox (Enoxaparin), they won't completely work.
  • It doesn't work as well as other medications for "thinning the blood" if you are overweight, underweight, or if you have kidney disease.
  • You can bruise easier and if you cut yourself, it'll take longer to stop the bleeding. Always look for signs of internal bleeding, such as dark urine or bloody stools.
  • Can't be used if you have artificial heart valves.
  • Never stop taking Eliquis (apixaban) without talking to your doctor first.
  • Eliquis (apixaban) isn't available as a generic, so it can be expensive.
  • If you've taken too much Eliquis (apixaban) and you're bleeding, it can be harder to treat compared to other blood thinners.
Used for
Dosage forms
  • Injection
  • Pill
Price
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Reviews
19 reviews so far
63%
saidit'sworth it
63%
saiditworked well
16%
saidit'sa big hassle

Have you used Lovenox (Enoxaparin)?

Leave a review
19 reviews so far
47%
saidit'sworth it
58%
saiditworked well
21%
saidit'sa big hassle

Have you used Eliquis (apixaban)?

Leave a review
Side effects
7possible side effects
  • Fever
    5%
  • Major hemorrhage
    4%
  • Hemorrhage
    4%
  • Nausea
    3%
  • Peripheral edema
    3%
  • Anemia
    2%
  • Edema
    2%
See more detailed side effects
1possible side effects
  • Major bleed
    2%
See more detailed side effects
Risks and risk factors
  • Blood clot in the spine
    • Spinal puncture (spinal tap)
    • Getting anesthesia in the spine (epidural anesthesia)
    • Taking NSAIDs or other blood thinning medicines
  • Unusual bleeding
    • History of bleeding problems
    • Severe high blood pressure
    • Older age
  • Increased risk of stroke or increased risk of blood clots
    • Stopping Lovenox (Enoxaparin) early
  • Clotting problems
    • Heparin-induced thrombocytopenia
See more detailed risks and warnings
  • Increased risk of stroke or blood clots from early discontinuation
    • Stopping Eliquis (apixaban) prematurely
  • Paralysis in the spine
    • Spinal puncture (spinal tap)
    • Getting anesthesia in the spine (epidural anesthesia)
    • History of spinal surgery
    • Concomitant use of nonsteroidal anti-inflammatory drugs (NSAIDs), or other blood-thinners
  • Interactions with other drugs
  • Increased risk of stroke or bleeding
    • Artificial heart valve
  • Increased side effects in kidney or liver conditions
    • Current kidney problems
    • Current liver problems
See more detailed risks and warnings