Compare Lovenox vs. Xarelto

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lovenox (Enoxaparin)

Prescription only

Xarelto (rivaroxaban)

Prescription only
Prevents blood clots.

Lovenox (Enoxaparin) is a good anticoagulant that reduces the risk of death or bleeding, and blood clots are less likely to happen. However, it is only available as an injection which isn't great if you're afraid of needles.

4.0/ 5 average rating with 19 reviewsforLovenox
Prevents blood clots.

Xarelto (rivaroxaban) is a good medication for preventing blood clots. It doesn't require regular blood tests or changing doses often. However, it can be expensive and there's no way to reverse the medication's effects.

3.5/ 5 average rating with 22 reviewsforXarelto
Upsides
  • In a study that compared Lovenox (Enoxaparin) to other medications used to stop blood clots, there was a lower risk of clots coming back, with similar rates of major bleeding and mortality.
  • You don't need to go in for lab tests to check whether it's working, unlike other medications like warfarin that require regular blood draws.
  • Available in generic so it can be cheaper than other "blood thinners".
  • Good option if you're pregnant or have cancer.
  • Studies show that Xarelto (rivaroxaban) works just as well as other blood thinners (anticoagulants) in preventing strokes and stopping clots from froming.
  • Xarelto (rivaroxaban) doesn't require regular blood tests or frequent dose changes.
  • Xarelto (rivaroxaban) doesn't interact with as many types of food as other blood thinners like warfarin (Coumadin).
Downsides
  • It is only available as an injection, so it's not great if you're afraid of needles.
  • While surprise bleeding episodes can be treated while taking Lovenox (Enoxaparin), they won't completely work.
  • It doesn't work as well as other medications for "thinning the blood" if you are overweight, underweight, or if you have kidney disease.
  • Xarelto (rivaroxaban) can increase your risk of bleeding, so call your doctor right away if you see blood in your spit, urine, or stool (look for black, tarry stools or bright red blood).
  • Xarelto (rivaroxaban) isn't available as a generic medication.
  • There are no antidotes to stop bleeding caused by taking too much Xarelto (rivaroxaban).
  • You can't take Xarelto (rivaroxaban) if you are pregnant.
Used for
Dosage forms
  • Injection
  • Pill
Price
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Reviews
19 reviews so far
63%
saidit'sworth it
63%
saiditworked well
16%
saidit'sa big hassle

Have you used Lovenox (Enoxaparin)?

Leave a review
22 reviews so far
45%
saidit'sworth it
45%
saiditworked well
9%
saidit'sa big hassle

Have you used Xarelto (rivaroxaban)?

Leave a review
Side effects
7possible side effects
  • Fever
    5%
  • Major hemorrhage
    4%
  • Hemorrhage
    4%
  • Nausea
    3%
  • Peripheral edema
    3%
  • Anemia
    2%
  • Edema
    2%
See more detailed side effects
2possible side effects
  • Major bleeding needing transfusion
    4%
  • Bleeding in the stomach & intestines
    2%
See more detailed side effects
Risks and risk factors
  • Blood clot in the spine
    • Spinal puncture (spinal tap)
    • Getting anesthesia in the spine (epidural anesthesia)
    • Taking NSAIDs or other blood thinning medicines
  • Unusual bleeding
    • History of bleeding problems
    • Severe high blood pressure
    • Older age
  • Increased risk of stroke or increased risk of blood clots
    • Stopping Lovenox (Enoxaparin) early
  • Clotting problems
    • Heparin-induced thrombocytopenia
See more detailed risks and warnings
  • Blood clots and stroke
    • Stopping Xarelto (rivaroxaban) too soon
    • Artificial heart valve
  • Blood clot in the spine
    • Spinal puncture (spinal tap)
    • Getting anesthesia in the spine (epidural anesthesia)
  • Unusual bleeding
    • History of bleeding problems
    • Severe high blood pressure
    • Age 65 or older
    • Drug interactions
    • Taking NSAIDs, aspirin, or other blood-thinning medicines
  • Increased side effects
    • Current kidney problems
    • Current liver problems
See more detailed risks and warnings