Compare Lunesta vs. Rozerem

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lunesta
(Eszopiclone)

Rozerem
(Ramelteon)

Helps you sleep. Lunesta (Eszopiclone) is good for falling asleep and staying asleep. Not as habit-forming as some sleep medicines, but more likely to cause withdrawal symptoms if you stop suddenly.Coming soon.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.47Lunesta
Reviews for Lunesta (Eszopiclone)
55%
of people (All ages) say Lunesta (Eszopiclone) is worth it
36%
say it works well
17%
say it's a big hassle
592 reviews
Have you used Lunesta (Eszopiclone)?
Worth itNot sureNot worth it

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Have you used Rozerem (Ramelteon)?
Worth itNot sureNot worth it
Side effects
LunestaRozerem
  • Headache 8%
  • Unpleasant taste 14%
  • Drowsiness 7%
  • Dizziness 1%
  • Nausea 1%
  • Infection 2%
  • Dry mouth 2%
  • Nervousness 2%
  • Low mood disorder 4%
More Lunesta side effects »

We haven’t found good data for Rozerem side effects.

FDA side effect reports for Rozerem »
How it works
LunestaRozerem
Lunesta (Eszopiclone) is in a class of drugs called sedative-hypnotics. Researchers don't know exactly how it works, but it interacts with your brain to make you relaxed and sleepy.Coming soon.
Type of medication
LunestaRozerem
Prescription only
Available as
LunestaRozerem
  • Pill
  • Pill
Used for
LunestaRozerem
  • Insomnia
Risk factors for serious side effects
LunestaRozerem
  • Continuous use for 2 weeks or more
  • Alcohol
  • Taking other medicines that make you less alert
  • Less than 7 hours of sleep.
  • Undiagnosed psychiatric conditions
  • Taking with alcohol or drugs that acts in the brain
    • Elderly
    • Higher dose
    • Liver problems
    • Taking Lunesta (Eszopiclone) with other nervous system depressants
    • Long-term use
    • Women of childbearing age
    • Breast-feeding
    Detailed Lunesta (Eszopiclone) risks & warnings »
    Coming soon.
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Alcohol
    LunestaRozerem
    • Might not be safe if you have a history of drug or alcohol abuse, depression, lung disease, or a condition that affects metabolism.
    • Avoid alcohol and drugs.
    No alcohol related info.
    Sleep
    LunestaRozerem
    • Effective at helping people fall asleep faster and sleep longer.
    • Only take it if you have time to sleep for at least 7 hours.
    • Can cause headache, drowsiness, and dizziness.
    • Lunesta (Eszopiclone) make you feel drowsy and sleepy, leading to falls and severe injuries. This is especially a risk if your older. Falls from sleep medicines like Lunesta (Eszopiclone) have caused severe injuries such as hip fractures and head injury. You may need a lower dose if you're taking other medicine that affects your nervous system or have issues with falls in the past. Check with your doctor first.
    No sleep related info.
    Upsides and benefits
    LunestaRozerem
    • Effective at helping people fall asleep faster and sleep longer.
    • Not as habit-forming, so you can use it for longer than most other sleep medicines.
    Coming soon
    Downsides and risks
    LunestaRozerem
    • More likely to cause withdrawal symptoms if you stop taking it suddenly.
    • Might not be safe if you have a history of drug or alcohol abuse, depression, lung disease, or a condition that affects metabolism.
    • It's easy to become reliant on sleep medicines. In the long run, it's better to learn good sleeping habits and behavior so that you can sleep better naturally.
    Coming soon
    Tips from our pharmacists for people taking the medication
    LunestaRozerem
    • Take 30 to 45 minutes before bedtime.
    • Only take it if you have time to sleep for at least 7 hours.
    • Very addictive. Meant for short-term treatment. Dependence can form after daily use for 2 weeks.
    • Can cause headache, drowsiness, and dizziness.
    • Can cause sleep-walking, sleep-driving, and sleep-eating.
    • Works best if taken without food.
    • Avoid alcohol and drugs.
    • Withdrawal symptoms usually resolve in 1 to 2 nights.
    • Report any confusion or changes in thoughts or behavior.
    Coming soon
    Learn more
    More about LunestaSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Lunesta (Eszopiclone)?
    Worth itNot sureNot worth it
    More about RozeremSide effectsFDA package insert
    Have you used Rozerem (Ramelteon)?
    Worth itNot sureNot worth it