Compare maprotiline vs. Pamelor

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Ludiomil
(maprotiline)

Pamelor
(nortriptyline)

Stabilizes your mood. While Ludiomil (maprotiline) is part of the first choice of medicines to treat depression, it can cause drowsiness and dehydration.Improves your mood. Pamelor (Nortriptyline) is a good option for treating depression, especially for people who also have problems with persistent nerve pain.
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Coupons for maprotiline
Best available price for 30 (50mg) tablets of maprotiline
Coupons for Pamelor
Best available price for 30 (10mg) capsules of nortriptyline
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
Reviews for Ludiomil (maprotiline)
Not enough review data. Review it!
of people (All ages) say Ludiomil (maprotiline) is worth it
Not enough review data. Review it!
say it works well
Not enough review data. Review it!
say it's a big hassle
Have you used Ludiomil (maprotiline)?
Worth itNot sureNot worth it
Reviews for Pamelor (nortriptyline)
79%
+79% better vs. Ludiomil (maprotiline)
79%
+79% better vs. Ludiomil (maprotiline)
21%
-21% worse vs. Ludiomil (maprotiline)
Have you used Pamelor (nortriptyline)?
Worth itNot sureNot worth it
Side effects
maprotilinePamelor
  • Dry mouth 22%
  • Drowsiness 16%
  • Dizziness 8%
  • Constipation 6%
  • Nervousness 6%
  • Weakness & fatigue 4%
  • Headache 4%
  • Vision changes 4%
  • Anxiety 3%
  • Difficulty controlling movements 3%
More maprotiline side effects »

We haven’t found good data for Pamelor side effects.

FDA side effect reports for Pamelor »
How it works
maprotilinePamelor
Ludiomil (maprotiline) is a tricyclic antidepressant. It raises the amount of norepinephrine in the brain, which is believed to be one of the chemicals that regulates mood.Pamelor (Nortriptyline) is a tricyclic antidepressant (TCA). It helps improve your mood by altering the levels of serotonin, norepinephrine, and other similar chemicals in your brain.
Type of medication
maprotilinePamelor
Prescription only
Prescription only
Available as
maprotilinePamelor
  • Pill
  • Pill
  • Liquid
Used for
maprotilinePamelor
Risk factors for serious side effects
maprotilinePamelor
  • People under age 24
  • History of heart attack or heart disease
Detailed Ludiomil (maprotiline) risks & warnings »
  • Age 24 years or younger
  • Age 65 years or older
  • Stopping Pamelor (Nortriptyline) suddenly
  • Using other medications that affect serotonin
  • History of heart disease
Detailed Pamelor (nortriptyline) risks & warnings »
Pregnancy

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

Food
maprotilinePamelor
No food related info.
  • Take it with food and/or at bedtime to decrease the potential side effects.
Weight
maprotilinePamelor
  • Ludiomil (maprotiline) can cause weight gain, fainting, and make you feel dehydrated.
No weight related info.
Upsides and benefits
maprotilinePamelor
  • Ludiomil (maprotiline) is available in generic.
  • Ludiomil (maprotiline) doesn't cause sleep problems, unlike other medicines used to treat depression.
  • Helpful with treating certain types of pain, like migraines or nerve-related pain.
  • Generally well tolerated and has fewer side effects than other medicines in the same class of drugs.
Downsides and risks
maprotilinePamelor
  • Ludiomil (maprotiline) can make you very drowsy compared to other similar medicines.
  • Ludiomil (maprotiline) can cause weight gain, fainting, and make you feel dehydrated.
  • Stopping Ludiomil (maprotiline) suddenly without telling your doctor can be dangerous.
  • You might not notice changes in your mood until you've taken Ludiomil (maprotiline) for several weeks.
  • Side effects are usually manageable, but can be annoying.
  • Increases the risk of falls, especially when used in the elderly.
  • There's an increased chance of it causing heart problems, especially in people with a history of heart problems.
Tips from our pharmacists for people taking the medication
maprotilinePamelor
  • If you've taken Ludiomil (maprotiline) for a long time, don't stop taking it suddenly without talking to your doctor first. It can be very dangerous.
  • Don't drive or do anything requiring concentration while taking Ludiomil (maprotiline) until you know how it affects you since it can make you sleepy. This can be worse if you drink alcohol or take narcotics.
  • You might not notice changes in your mood until you've taken Ludiomil (maprotiline) for at least a few weeks.
  • If you forget your regular dose of Ludiomil (maprotiline), take it as soon as you remember. However, don't take 2 doses at the same time if it's already time for your next dose.
  • You might feel dizzy the first few days you take Ludiomil (maprotiline), which can make you fall. Be very careful getting up if you've been sitting or lying down for a while. Brace yourself and sit back down if you're feeling dizzy.
  • Ludiomil (maprotiline) can also cause constipation. Eat plenty of fruits and vegetables, or use stool softeners or laxatives.
  • Needs to be taken every day for 1 to 2 weeks to start feeling better, and for 6 to 8 weeks to see the full effect of the medication.
  • It's important to keep taking Pamelor (Nortriptyline) even when you feel your symptoms are getting better.
  • Take it with food and/or at bedtime to decrease the potential side effects.
  • Tell your doctor if you notice sudden mood changes or unusual thoughts.
  • If you decide to stop taking Pamelor (Nortriptyline), work with your doctor to slowly get off this medicine to avoid getting withdrawal symptoms.
Learn more
More about maprotilineSide effectsAlternativesFDA package insert
Have you used Ludiomil (maprotiline)?
Worth itNot sureNot worth it
More about PamelorSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Pamelor (nortriptyline)?
Worth itNot sureNot worth it