Compare meloxicam vs. Acetaminophen With Codeine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Mobic
(meloxicam)

Tylenol #3
(acetaminophen / codeine)

Relieves pain and inflammation. Mobic (meloxicam) works well for pain and inflammation and you only take it once a day, but you need a prescription.Treats mild to moderate pain. Tylenol #3 (Acetaminophen / Codeine) is a good option to treat pain and cough as needed when over-the-counter medicines can't control the symptoms, but must make sure you don't take too much acetaminophen (Tylenol) to avoid liver problems or death.
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Prices and coupon for 30 (15mg) tablets of meloxicam
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Prices and coupon for 20 (300mg/30mg) tablets of acetaminophen / codeine
Reviews & ratings
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5.13meloxicam
Reviews for Mobic (meloxicam)
64%
of people (All ages) say Mobic (meloxicam) is worth it
54%
say it works well
13%
say it's a big hassle
141 reviews
Have you used Mobic (meloxicam)?
Worth itNot sureNot worth it
Reviews for Tylenol #3 (acetaminophen / codeine)
69%
+5% better vs. Mobic (meloxicam)
41%
-13% worse vs. Mobic (meloxicam)
9%
+4% better vs. Mobic (meloxicam)
581 reviews
Have you used Tylenol #3 (acetaminophen / codeine)?
Worth itNot sureNot worth it
Side effects
meloxicamAcetaminophen With Codeine
  • Indigestion 10%
  • Ear, nose, or throat infection 8%
  • Nausea 7%
  • Urinary tract infection 7%
  • Pain 5%
  • Abdominal pain 3%
  • Constipation 3%
  • Diarrhea 3%
  • Gas 3%
  • Vomiting 3%
More meloxicam side effects »

The Acetaminophen With Codeine FDA package insert doesn’t have numbers about how common side effects are.

More about Acetaminophen With Codeine side effects »
How it works
meloxicamAcetaminophen With Codeine
Mobic (meloxicam) is a non-steroidal anti-inflammatory drug (NSAID). It blocks the inflammation process in your body, which relieves pain and swelling.Tylenol #3 (Acetaminophen / Codeine) is a combination pain medicine. Codeine is an opioid (similar to morphine) that works in the brain to lower pain perception. Acetaminophen is a non-opioid pain reliever and fever reducer.
Type of medication
meloxicamAcetaminophen With Codeine
Prescription only
Prescription only
Available as
meloxicamAcetaminophen With Codeine
  • Pill
  • Suspension
  • Pill
  • Liquid
Used for
meloxicamAcetaminophen With Codeine
Risk factors for serious side effects
meloxicamAcetaminophen With Codeine
  • History of heart problems
  • Taking the medicine for a long period of time
  • History of stomach bleeding
  • Age 60 or older
  • Taking aspirin, other NSAIDs, or blood thinners
  • Drinking more than 3 alcoholic beverages a day
  • Smoking
  • Taking the medicine for a long time
  • Asthma
  • Nasal polyps
  • Aspirin allergy
  • NSAID allergy
  • Kidney disease
  • Heart failure
  • Liver disease
  • Taking certain high blood pressure medications
  • Age 60 or older
  • Taking the medicine for a long period of time
  • Women who want to or can become pregnant
  • Pregnant women
Detailed Mobic (meloxicam) risks & warnings »
Coming soon.
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Alcohol
meloxicamAcetaminophen With Codeine
No alcohol related info.
  • Avoid alcohol.
Food
meloxicamAcetaminophen With Codeine
  • It should be taken only once a day, with food or milk to prevent stomach upset.
  • Take it with food to lower the chance of an upset stomach.
Kidneys and liver
meloxicamAcetaminophen With Codeine
  • Mobic (meloxicam) can damage your kidneys if you take it for a very long time. Taking the lowest dose for the shortest amount of time lowers your risk. Talk to your doctor if this worries you, or if you already have kidney damage before you start taking Mobic (meloxicam).
  • Don't take more than instructed to prevent liver damage.
Pain
meloxicamAcetaminophen With Codeine
  • Works well to relieve pain and inflammation due to osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
  • Mobic (meloxicam) can cause stomach bleeding which can be dangerous. If you notice blood in your vomit or your stool has bright red blood or looks like black coffee grounds, or if you have pain in your stomach that doesn't go away, talk to your doctor right away.
  • Combination pain medicine with an opioid component (codeine) and non-opioid component (acetaminophen or Tylenol) that takes advantage of different modes of pain relieve in a single pill.
  • Good for as-needed pain and control.
  • This is a combination pain medication. It contains both an opioid medicine, and acetaminophen (Tylenol).
  • Works best if you take it as soon as you start feeling pain.
  • Pain relief lasts 4-6 hours.
Sleep
meloxicamAcetaminophen With Codeine
No sleep related info.
  • Can help you fall asleep easier.
  • Dizziness and drowsiness is common, but your body may adjust.
Upsides and benefits
meloxicamAcetaminophen With Codeine
  • Taken only once a day, while other NSAIDS need to be taken a few times a day for the same effect.
  • Works well to relieve pain and inflammation due to osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
  • Causes less stomach upset than other NSAIDs.
  • Relatively cheap compared to other prescription NSAIDS.
  • Combination pain medicine with an opioid component (codeine) and non-opioid component (acetaminophen or Tylenol) that takes advantage of different modes of pain relieve in a single pill.
  • Provides quick relieve for mild to moderate pain to improve quality of life.
  • Good for as-needed pain and control.
  • Generally well tolerated by people, especially if taken with food to lower risk of stomach upset.
  • Lower rates of misuse compared to pure opioid medicines.
  • Can help you fall asleep easier.
Downsides and risks
meloxicamAcetaminophen With Codeine
  • Mobic (meloxicam) does not kick in as fast as other NSAIDS.
  • It's available by prescription only.
  • Mobic (meloxicam) is not as safe as other alternatives for pregnant women and people who are age 60 or older.
  • It can cause serious complications like stomach bleeding and kidney problems if taken for a long time.
  • Dizziness and drowsiness is common, but your body may adjust.
  • Everyone will get constipation - always stay hydrated and take stool softener or stimulant on days you're taking Acetaminophen with codeine if you need.
  • All opioid containing medicines have the risk of physical dependence and possibility of withdrawal when used long-term.
  • The non-opioid part of Acetaminophen with codeine, acetaminophen (Tylenol), has a high risk of liver failure and death if you take more than the maximum daily dose. Be very careful.
  • Relies on the users to be aware of how much acetaminophen (Tylenol) they are using since it is a very common ingredient in many prescription and non-prescription pain medicines.
  • Avoid alcohol.
Tips from our pharmacists for people taking the medication
meloxicamAcetaminophen With Codeine
  • It should be taken only once a day, with food or milk to prevent stomach upset.
  • Mobic (meloxicam) increases the risk of stomach bleeding so tell your doctor right away if you experience any bleeding.
  • Do not take Mobic (meloxicam) with any blood thinners unless your doctor says so.
  • If you are allergic to aspirin, you may be allergic to Mobic (meloxicam) as well.
  • The capsule, suspension, and tablet forms of the medicine come in different strengths, so be careful when switching from one form to another.
  • This is a combination pain medication. It contains both an opioid medicine, and acetaminophen (Tylenol).
  • Starts working in 30 minutes.
  • Works best if you take it as soon as you start feeling pain.
  • Pain relief lasts 4-6 hours.
  • Can make you dizzy or drowsy.
  • Avoid activities need you to be fully alert until you know how it affects you.
  • Take it with food to lower the chance of an upset stomach.
  • Constipation is common and may not go away while you're taking this medicine. Drinking lots of water and using laxatives can help.
  • Don't take more than instructed to prevent liver damage.
  • Use it for the shortest time possible, and at the lowest dose possible, to lower your chance of becoming addicted.
  • Talk to your doctor if it doesn't help enough for your pain, or if the side effects are really bad.
Learn more
More about meloxicamSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Mobic (meloxicam)?
Worth itNot sureNot worth it
More about Acetaminophen With CodeineSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Tylenol #3 (acetaminophen / codeine)?
Worth itNot sureNot worth it