Compare meloxicam vs. Morphine Sulfate

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Mobic
(meloxicam)

Ms Contin
(morphine sulfate)

Relieves pain and inflammation. Mobic (meloxicam) works well for pain and inflammation and you only take it once a day, but you need a prescription.Treats severe pain. Ms Contin (Morphine Sulfate) provides good long-term pain control without the need to take medicine frequently, but watch out for constipation.
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Reviews & ratings
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5.13meloxicam
Reviews for Mobic (meloxicam)
64%
of people (All ages) say Mobic (meloxicam) is worth it
54%
say it works well
13%
say it's a big hassle
141 reviews
Have you used Mobic (meloxicam)?
Worth itNot sureNot worth it
Reviews for Ms Contin (morphine sulfate)
55%
-9% worse vs. Mobic (meloxicam)
43%
-11% worse vs. Mobic (meloxicam)
20%
-7% worse vs. Mobic (meloxicam)
541 reviews
Have you used Ms Contin (morphine sulfate)?
Worth itNot sureNot worth it
Side effects
meloxicamMorphine Sulfate
  • Indigestion 10%
  • Ear, nose, or throat infection 8%
  • Nausea 7%
  • Urinary tract infection 7%
  • Pain 5%
  • Abdominal pain 3%
  • Constipation 3%
  • Diarrhea 3%
  • Gas 3%
  • Vomiting 3%
More meloxicam side effects »

The Morphine Sulfate FDA package insert doesn’t have numbers about how common side effects are.

More about Morphine Sulfate side effects »
How it works
meloxicamMorphine Sulfate
Mobic (meloxicam) is a non-steroidal anti-inflammatory drug (NSAID). It blocks the inflammation process in your body, which relieves pain and swelling.Ms Contin (Morphine Sulfate) is an opioid medicine that works in the brain to lower pain perception.
Type of medication
meloxicamMorphine Sulfate
Prescription only
Prescription only
Available as
meloxicamMorphine Sulfate
  • Pill
  • Suspension
  • Pill
  • Extended release
  • Oral solution
  • Liquid
  • Suppository
Used for
meloxicamMorphine Sulfate
Risk factors for serious side effects
meloxicamMorphine Sulfate
  • History of heart problems
  • Taking the medicine for a long period of time
  • History of stomach bleeding
  • Age 60 or older
  • Taking aspirin, other NSAIDs, or blood thinners
  • Drinking more than 3 alcoholic beverages a day
  • Smoking
  • Taking the medicine for a long time
  • Asthma
  • Nasal polyps
  • Aspirin allergy
  • NSAID allergy
  • Kidney disease
  • Heart failure
  • Liver disease
  • Taking certain high blood pressure medications
  • Age 60 or older
  • Taking the medicine for a long period of time
  • Women who want to or can become pregnant
  • Pregnant women
Detailed Mobic (meloxicam) risks & warnings »
  • Current use of medicine that affects liver enzyme CYP 3A4
  • Age 65 or greater
  • Higher dose
  • People with not enough thyroid hormones
  • History of lung problems
  • Children age 18 and younger
  • Long-term use during pregnancy
  • Taking more than the prescribed dose
  • Long-term use
  • History of drug abuse
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • Age 65 or greater
  • Age 65 years or older
Detailed Ms Contin (morphine sulfate) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Food
meloxicamMorphine Sulfate
  • It should be taken only once a day, with food or milk to prevent stomach upset.
  • Take it with food to lower the chance of an upset stomach.
Kidneys and liver
meloxicamMorphine Sulfate
  • Mobic (meloxicam) can damage your kidneys if you take it for a very long time. Taking the lowest dose for the shortest amount of time lowers your risk. Talk to your doctor if this worries you, or if you already have kidney damage before you start taking Mobic (meloxicam).
No kidneys and liver related info.
Pain
meloxicamMorphine Sulfate
  • Works well to relieve pain and inflammation due to osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
  • Mobic (meloxicam) can cause stomach bleeding which can be dangerous. If you notice blood in your vomit or your stool has bright red blood or looks like black coffee grounds, or if you have pain in your stomach that doesn't go away, talk to your doctor right away.
  • Good for chronic pain that requires around-the-clock relief.
  • Doesn't work for as-needed or quick pain relief.
Sleep
meloxicamMorphine Sulfate
No sleep related info.
  • Dizziness and drowsiness is common, but your body may adjust.
Upsides and benefits
meloxicamMorphine Sulfate
  • Taken only once a day, while other NSAIDS need to be taken a few times a day for the same effect.
  • Works well to relieve pain and inflammation due to osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
  • Causes less stomach upset than other NSAIDs.
  • Relatively cheap compared to other prescription NSAIDS.
  • Provides longer relieve for moderate to severe pain to improve quality of life.
  • Good for chronic pain that requires around-the-clock relief.
  • Might have fewer side effects than other opioid pain relievers.
Downsides and risks
meloxicamMorphine Sulfate
  • Mobic (meloxicam) does not kick in as fast as other NSAIDS.
  • It's available by prescription only.
  • Mobic (meloxicam) is not as safe as other alternatives for pregnant women and people who are age 60 or older.
  • It can cause serious complications like stomach bleeding and kidney problems if taken for a long time.
  • Doesn't work for as-needed or quick pain relief.
  • Dizziness and drowsiness is common, but your body may adjust.
  • Everyone will get constipation - always stay hydrated and take stool softener or stimulant on days you're taking Ms Contin (Morphine Sulfate) if you need.
  • Long term use will likely cause physical dependence.
  • Must be weaned slowly off the medicine after use longer than 2 weeks.
Tips from our pharmacists for people taking the medication
meloxicamMorphine Sulfate
  • It should be taken only once a day, with food or milk to prevent stomach upset.
  • Mobic (meloxicam) increases the risk of stomach bleeding so tell your doctor right away if you experience any bleeding.
  • Do not take Mobic (meloxicam) with any blood thinners unless your doctor says so.
  • If you are allergic to aspirin, you may be allergic to Mobic (meloxicam) as well.
  • The capsule, suspension, and tablet forms of the medicine come in different strengths, so be careful when switching from one form to another.
  • Opioid pain medicine that provides longer pain relief—up to 12 hours.
  • Works best when taken regularly instead of as-needed.
  • Especially useful for people with chronic pain problems.
  • May not be the best choice for people who have never taken an opioid pain medicine because it lasts so long.
  • Swallow it whole. Don't crush, chew, or split the medicine.
  • Can make you dizzy or drowsy.
  • Avoid activities that need you to be fully alert until you know how it affects you.
  • Take it with food to lower the chance of an upset stomach.
  • Constipation is common and may not go away while you're taking this medicine. Drinking lots of water and taking laxatives can help.
  • Talk to your doctor if it doesn't help enough for your pain, or if the side effects are really bad.
Learn more
More about meloxicamSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Mobic (meloxicam)?
Worth itNot sureNot worth it
More about Morphine SulfateSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Ms Contin (morphine sulfate)?
Worth itNot sureNot worth it