Compare Meloxicam vs. Tramadol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Mobic
(Meloxicam)

Ultram
(Tramadol)

Relieves pain and inflammation. Mobic (Meloxicam) works well for treating pain and causes less upset stomach than other NSAIDs.Treats moderate to severe pain. Ultram (Tramadol) works well to treat severe pain and mood changes. Although it's a little weaker than other opioids, it can still be addictive.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
4.951456310679611Meloxicam
Reviews for Mobic (Meloxicam)
56%
of people say Mobic (Meloxicam) is worth it
48%
say it works well
16%
say it's a big hassle
Reviews for Ultram (Tramadol)
61%
+5% vs. Mobic (Meloxicam)
39%
9% vs. Mobic (Meloxicam)
16%
Same vs. Mobic (Meloxicam)
Side effects
MeloxicamTramadol
  • Gastrointestinal disorders 5%
  • Diarrhea 4%
  • Infection and infestations 3%
  • Accident household 3%
  • Swelling due to excess fluid 2%
  • Dyspeptic signs and symptoms 2%
  • Sore throat 2%
  • Dizziness 1%
  • Flu-like symptomsa-like symptoms 1%
More Meloxicam side effects »
  • Dizziness (not vertigo) 21%
  • Flushing 12%
  • Itching 11%
  • Dry mouth 10%
  • Dizziness 9%
  • Sleep difficulty 8%
  • Positional low blood pressure 3%
More Tramadol side effects »
How it works
MeloxicamTramadol
Mobic (Meloxicam) is a non-steroidal anti-inflammatory drug (NSAID). It blocks the inflammation process in your body, which relieves swelling and pain.Ultram (Tramadol) is an atypical opioid pain reliever. Researchers don't know exactly how it works, but it alters certain brain chemicals to lower pain perception and improve mood.
Type of medication
MeloxicamTramadol
Pain reliever
Nonsteroidal anti-inflammatory drug (NSAID)
Prescription only
Pain reliever
Opioid
Prescription only
Available as
MeloxicamTramadol
  • Pill
  • Liquid
  • Pill
  • Extended release
  • Extended release capsule
  • Dissolving tablet
Used for (click to learn more)
MeloxicamTramadol
Risk factors for serious side effects
MeloxicamTramadol
  • History of heart attack
  • History of heart surgery
  • High blood pressure
  • High Cholesterol
  • Diabetes
  • Being Overweight or Obese
  • Smoking
  • History of stomach bleeding or ulcers
  • Age 65 or older
  • Hemophilia
  • von Willebrand's disease
  • Low blood platelet count
  • Also taking anticoagulant medication
  • Asthma
  • Rhinitis
  • Nasal Polyps
  • Aspirin Allergy
  • NSAID Allergy
  • Kidney Disease
  • Heart Failure
  • Liver Disease
  • Also taking diuretics
  • Also taking ACE inhibitors
  • Also taking Angiotensin Receptor Blockers (ARBs)
  • Age 65 or older
  • History of high blood pressure
  • Taking water pills (diuretics)
  • Late pregnancy (more than 30 weeks)
Detailed Mobic (Meloxicam) risks & warnings »
  • Higher dose
  • Using other medicines that can cause seizures
  • History of seizures
  • Alcoholism
  • Eating disorders
  • Brain infections
  • Suicidal or at risk
  • Taking other medications that affect serotonin
  • Drug or alcohol abuse
  • Using other medications that affect serotonin
  • History of allergic reactions to codeine or other opioid pain relievers
  • Phenylalanine sensitivity
  • Stopping Ultram (Tramadol) suddenly
  • Taking more than the prescribed dose
  • Taking with alcohol or drugs
  • Taking with alcohol or drugs
    Detailed Ultram (Tramadol) risks & warnings »
    Pregnancy category
    MeloxicamTramadol
    DFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    Alcohol
    No specific alcohol-related info.
    • Serious side effects may include drug abuse, dependence, slowed breathing rate (respiratory depression), and death. Don't take more than your doctor prescribes or take with alcohol, illegal drugs, or other opioid pain relievers.
    Food
    • Take Mobic (Meloxicam) only once a day. Take it with a meal or a snack to prevent an upset stomach.
    • Take Ultram (Tramadol) with food to avoid an upset stomach.
    Kidneys and liver
    • Can also affect your kidneys or cause permanent kidney damage if taken for a long time.
    • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
    • Mobic (Meloxicam), and similar medications in the NSAID family, can lower kidney function or cause permanent kidney damage. Taking the lowest dose for the shortest amount of time necessary can lower your risk for kidney problems. It is important to get lab tests to check your kidney function periodically if you use Mobic (Meloxicam) for long periods of time.
    • There are different doses for people who are older or who have liver or kidney disease, so work with your doctor to get the right dose.
    Sex
    No specific sex-related info.No specific sex-related info.
    Sleep
    No specific sleep-related info.
    • Can make you dizzy or drowsy, so avoid activities that need you to be fully alert until you know how this medicine affects you.
    Weight
    No specific weight-related info.No specific weight-related info.
    Upsides and benefits
    MeloxicamTramadol
    • Works well to relieve pain and inflammation from osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
    • Good for muscle aches and pains.
    • It lasts longer than Ibuprofen, so you can take it less often.
    • Causes less upset stomach than other NSAIDs, like Ibuprofen.
    • Can also caus less bruising or bleeding than other NSAIDs when taken at lower doses (7.5 mg per day or less).
    • Relieves moderate to severe pain. It has been shown to work as well as other opioid pain medications.
    • Compared to typical opioids, it provides unique pain relief and effects on your mood when taken regularly.
    • Has a lower chance of causing breathing problems compared to other typical opioids.
    • Doesn't cause as much constipation as other opioid pain medicines. Staying hydrated and taking laxatives can help treat this side effect.
    Downsides and risks
    MeloxicamTramadol
    • The longer you take Mobic (Meloxicam), the more likely you are to have stomach problems, including inflammation, ulcers, and bleeding. This can also happen if you take Mobic (Meloxicam) on an empty stomach.
    • Like all NSAIDs, it can raise your risk of blood clots, heart attack, or a stroke.
    • Can also affect your kidneys or cause permanent kidney damage if taken for a long time.
    • Some people think it's weaker than other opioid pain medications. It can also cause more upset stomach.
    • Like other opioid pain relievers, Tramadol has a high risk of addiction, abuse, misuse, overdose, and death. It should only be used for severe pain that requires daily, around-the-clock treatment once alternative treatments haven't worked.
    • It isn't used for short-term, as-needed pain relief.
    • It's a controlled substance regulated by the federal government. This means that your use of Ultram (Tramadol) will be tracked to prevent potential prescription abuse.
    • To get Ultram (Tramadol) in the pharmacy, you'll need to bring in a paper prescription directly from your doctor.
    Tips from our pharmacists for people taking the medication
    MeloxicamTramadol
    • Take Mobic (Meloxicam) only once a day. Take it with a meal or a snack to prevent an upset stomach.
    • Can make you bruise or bleed more easily and it can also cause stomach ulcers.
    • Don't take it with other blood thinners, like aspirin, unless your doctor tells you it's safe.
    • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
    • Starts working in one hour and works best if you take it regularly.
    • Can make you dizzy or drowsy, so avoid activities that need you to be fully alert until you know how this medicine affects you.
    • Take Ultram (Tramadol) with food to avoid an upset stomach.
    • There are different doses for people who are older or who have liver or kidney disease, so work with your doctor to get the right dose.
    • Swallow the extended-release tablets whole. They're designed to release the drug slowly and breaking, crushing, or chewing them could cause a serious overdose.
    Learn more
    More about MeloxicamSide effectsReviews & ratingsAlternativesFDA package insert
    More about TramadolSide effectsReviews & ratingsAlternativesFDA package insert