Compare Meloxicam vs. Tylenol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Mobic
(Meloxicam)

Tylenol Regular Strength
(Acetaminophen)

Relieves pain and inflammation. Mobic (Meloxicam) works well for treating pain and causes less upset stomach than other NSAIDs.Relieves pain and fever. Tylenol Regular Strength (Acetaminophen) reduces fever and relieves pain well, but it doesn't lower inflammation and swelling.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
4.951456310679611Meloxicam
Reviews for Mobic (Meloxicam)
56%
of people say Mobic (Meloxicam) is worth it
48%
say it works well
16%
say it's a big hassle
Reviews for Tylenol Regular Strength (Acetaminophen)
77%
+21% vs. Mobic (Meloxicam)
37%
11% vs. Mobic (Meloxicam)
3%
+13% vs. Mobic (Meloxicam)
Side effects
MeloxicamTylenol
  • Gastrointestinal disorders 5%
  • Diarrhea 4%
  • Infection and infestations 3%
  • Accident household 3%
  • Swelling due to excess fluid 2%
  • Dyspeptic signs and symptoms 2%
  • Sore throat 2%
  • Dizziness 1%
  • Flu-like symptomsa-like symptoms 1%
More Meloxicam side effects »

We haven’t found good data for Tylenol side effects.

FDA side effect reports for Tylenol »
How it works
MeloxicamTylenol
Mobic (Meloxicam) is a non-steroidal anti-inflammatory drug (NSAID). It blocks the inflammation process in your body, which relieves swelling and pain.Tylenol Regular Strength (Acetaminophen) reduces fever and relieves pain, but doesn't lower inflammation and swelling.
Type of medication
MeloxicamTylenol
Pain reliever
Nonsteroidal anti-inflammatory drug (NSAID)
Prescription only
Pain reliever
Acetaminophen (APAP)
Over-the-counter
Available as
MeloxicamTylenol
  • Pill
  • Liquid
  • Pill
  • Extended release tablet
  • Chewable tablet
  • Dissolving tablet
  • Gelcap
  • Liquid
  • Suppository
Used for (click to learn more)
MeloxicamTylenol
Risk factors for serious side effects
MeloxicamTylenol
  • History of heart attack
  • History of heart surgery
  • High blood pressure
  • High Cholesterol
  • Diabetes
  • Being Overweight or Obese
  • Smoking
  • History of stomach bleeding or ulcers
  • Age 65 or older
  • Hemophilia
  • von Willebrand's disease
  • Low blood platelet count
  • Also taking anticoagulant medication
  • Asthma
  • Rhinitis
  • Nasal Polyps
  • Aspirin Allergy
  • NSAID Allergy
  • Kidney Disease
  • Heart Failure
  • Liver Disease
  • Also taking diuretics
  • Also taking ACE inhibitors
  • Also taking Angiotensin Receptor Blockers (ARBs)
  • Age 65 or older
  • History of high blood pressure
  • Taking water pills (diuretics)
  • Late pregnancy (more than 30 weeks)
Detailed Mobic (Meloxicam) risks & warnings »
  • Drinking more than 2 alcoholic beverages a day
  • Taking with other Tylenol-containing medicines
  • History of liver disease
Detailed Tylenol Regular Strength (Acetaminophen) risks & warnings »
Pregnancy category
MeloxicamTylenol
DFDA pregnancy category (Weigh risks vs. benefits)

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
NFDA pregnancy category (Unknown)

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

See the FDA package insert
Alcohol
No specific alcohol-related info.
  • Drinking alcohol while taking Tylenol Regular Strength (Acetaminophen) can damage your liver.
  • Heavy alcohol drinkers shouldn't use Tylenol Regular Strength (Acetaminophen) since it can cause serious liver damage.
Food
  • Take Mobic (Meloxicam) only once a day. Take it with a meal or a snack to prevent an upset stomach.
No specific food-related info.
Kidneys and liver
  • Can also affect your kidneys or cause permanent kidney damage if taken for a long time.
  • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
  • Mobic (Meloxicam), and similar medications in the NSAID family, can lower kidney function or cause permanent kidney damage. Taking the lowest dose for the shortest amount of time necessary can lower your risk for kidney problems. It is important to get lab tests to check your kidney function periodically if you use Mobic (Meloxicam) for long periods of time.
  • Doesn't cause kidney damage and is safe to use if you have heart problems or if you're pregnant.
Sex
No specific sex-related info.No specific sex-related info.
Sleep
No specific sleep-related info.No specific sleep-related info.
Weight
No specific weight-related info.No specific weight-related info.
Upsides and benefits
MeloxicamTylenol
  • Works well to relieve pain and inflammation from osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
  • Good for muscle aches and pains.
  • It lasts longer than Ibuprofen, so you can take it less often.
  • Causes less upset stomach than other NSAIDs, like Ibuprofen.
  • Can also caus less bruising or bleeding than other NSAIDs when taken at lower doses (7.5 mg per day or less).
  • Works well to relieve pain and fevers.
  • Good for menstrual cramps, toothaches, body aches, and mild arthritis pain.
  • Tylenol Regular Strength (Acetaminophen) causes less upset stomach, ulcers, bruising, and bleeding than other pain medications like aspirin, ibuprofen, and naproxen.
  • Doesn't cause kidney damage and is safe to use if you have heart problems or if you're pregnant.
  • Although not without side effects, it's been around for a long time and is generally safe for short-term use.
Downsides and risks
MeloxicamTylenol
  • The longer you take Mobic (Meloxicam), the more likely you are to have stomach problems, including inflammation, ulcers, and bleeding. This can also happen if you take Mobic (Meloxicam) on an empty stomach.
  • Like all NSAIDs, it can raise your risk of blood clots, heart attack, or a stroke.
  • Can also affect your kidneys or cause permanent kidney damage if taken for a long time.
  • Tylenol Regular Strength (Acetaminophen) doesn't treat pain as well as other medications like ibuprofen and naproxen.
  • Drinking alcohol while taking Tylenol Regular Strength (Acetaminophen) can damage your liver.
  • To avoid hurting your liver, you need to keep track of the total amount of acetaminophen (APAP) you are taking since it's a very common ingredient in pain and cold/flu combination medicines.
  • Heavy alcohol drinkers shouldn't use Tylenol Regular Strength (Acetaminophen) since it can cause serious liver damage.
Tips from our pharmacists for people taking the medication
MeloxicamTylenol
  • Take Mobic (Meloxicam) only once a day. Take it with a meal or a snack to prevent an upset stomach.
  • Can make you bruise or bleed more easily and it can also cause stomach ulcers.
  • Don't take it with other blood thinners, like aspirin, unless your doctor tells you it's safe.
  • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
  • Starts working in one hour.
  • Contains acetaminophen, also known as Tylenol or APAP. Taking too much can cause liver failure and death. Don't take more than what's recommended on the package or with other Tylenol-containing products.
  • Follow age-specific dosing instructions on how much to take. Adults should never take more than 3,000 milligrams (mg) in a single day.
  • Let your doctor know if your symptoms don't improve in a few days.
Learn more
More about MeloxicamSide effectsReviews & ratingsAlternativesFDA package insert
More about TylenolSide effectsReviews & ratingsAlternativesFDA package insert