Compare meloxicam vs. Tylenol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Mobic
(meloxicam)

Tylenol Regular Strength
(acetaminophen)

Relieves pain and inflammation. Mobic (meloxicam) works well for pain and inflammation and you only take it once a day, but you need a prescription.Relieves pain and fever. Tylenol Regular Strength (Acetaminophen) reduces fever and relieves pain well, but it doesn't lower inflammation and swelling.
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Prices and coupon for 30 (15mg) tablets of meloxicam
Coupons for
Prices and coupon for 30 (325mg) tablets of acetaminophen
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.13meloxicam
Reviews for Mobic (meloxicam)
64%
of people (All ages) say Mobic (meloxicam) is worth it
54%
say it works well
13%
say it's a big hassle
141 reviews
Have you used Mobic (meloxicam)?
Worth itNot sureNot worth it
Reviews for Tylenol Regular Strength (acetaminophen)
77%
+13% better vs. Mobic (meloxicam)
37%
-17% worse vs. Mobic (meloxicam)
3%
+10% better vs. Mobic (meloxicam)
1002 reviews
Have you used Tylenol Regular Strength (acetaminophen)?
Worth itNot sureNot worth it
Side effects
meloxicamTylenol
  • Indigestion 10%
  • Ear, nose, or throat infection 8%
  • Nausea 7%
  • Urinary tract infection 7%
  • Pain 5%
  • Abdominal pain 3%
  • Constipation 3%
  • Diarrhea 3%
  • Gas 3%
  • Vomiting 3%
More meloxicam side effects »

We haven’t found good data for Tylenol side effects.

FDA side effect reports for Tylenol »
How it works
meloxicamTylenol
Mobic (meloxicam) is a non-steroidal anti-inflammatory drug (NSAID). It blocks the inflammation process in your body, which relieves pain and swelling.Tylenol Regular Strength (Acetaminophen) reduces fever and relieves pain, but doesn't lower inflammation and swelling.
Type of medication
meloxicamTylenol
Prescription only
Over-the-counter
Available as
meloxicamTylenol
  • Pill
  • Suspension
  • Pill
  • Extended release tablet
  • Chewable tablet
  • Dissolving tablet
  • Gelcap
  • Liquid
  • Suppository
Used for
meloxicamTylenol
Risk factors for serious side effects
meloxicamTylenol
  • History of heart problems
  • Taking the medicine for a long period of time
  • History of stomach bleeding
  • Age 60 or older
  • Taking aspirin, other NSAIDs, or blood thinners
  • Drinking more than 3 alcoholic beverages a day
  • Smoking
  • Taking the medicine for a long time
  • Asthma
  • Nasal polyps
  • Aspirin allergy
  • NSAID allergy
  • Kidney disease
  • Heart failure
  • Liver disease
  • Taking certain high blood pressure medications
  • Age 60 or older
  • Taking the medicine for a long period of time
  • Women who want to or can become pregnant
  • Pregnant women
Detailed Mobic (meloxicam) risks & warnings »
  • Drinking more than 2 alcoholic beverages a day
  • Taking with other Tylenol-containing medicines
  • History of liver disease
Detailed Tylenol Regular Strength (acetaminophen) risks & warnings »
Pregnancy

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

Alcohol
meloxicamTylenol
No alcohol related info.
  • Drinking alcohol while taking Tylenol Regular Strength (Acetaminophen) can damage your liver.
  • Heavy alcohol drinkers shouldn't use Tylenol Regular Strength (Acetaminophen) since it can cause serious liver damage.
Food
meloxicamTylenol
  • It should be taken only once a day, with food or milk to prevent stomach upset.
No food related info.
Kidneys and liver
meloxicamTylenol
  • Mobic (meloxicam) can damage your kidneys if you take it for a very long time. Taking the lowest dose for the shortest amount of time lowers your risk. Talk to your doctor if this worries you, or if you already have kidney damage before you start taking Mobic (meloxicam).
  • Doesn't cause kidney damage and is safe to use if you have heart problems or if you're pregnant.
  • To avoid hurting your liver, you need to keep track of the total amount of acetaminophen (APAP) you are taking since it's a very common ingredient in pain and cold/flu combination medicines.
Pain
meloxicamTylenol
  • Works well to relieve pain and inflammation due to osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
  • Mobic (meloxicam) can cause stomach bleeding which can be dangerous. If you notice blood in your vomit or your stool has bright red blood or looks like black coffee grounds, or if you have pain in your stomach that doesn't go away, talk to your doctor right away.
  • Works well to relieve pain and fevers.
  • To avoid hurting your liver, you need to keep track of the total amount of acetaminophen (APAP) you are taking since it's a very common ingredient in pain and cold/flu combination medicines.
Upsides and benefits
meloxicamTylenol
  • Taken only once a day, while other NSAIDS need to be taken a few times a day for the same effect.
  • Works well to relieve pain and inflammation due to osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
  • Causes less stomach upset than other NSAIDs.
  • Relatively cheap compared to other prescription NSAIDS.
  • Works well to relieve pain and fevers.
  • Good for menstrual cramps, toothaches, body aches, and mild arthritis pain.
  • Tylenol Regular Strength (Acetaminophen) causes less upset stomach, ulcers, bruising, and bleeding than other pain medications like aspirin, ibuprofen, and naproxen.
  • Doesn't cause kidney damage and is safe to use if you have heart problems or if you're pregnant.
  • Although not without side effects, it's been around for a long time and is generally safe for short-term use.
Downsides and risks
meloxicamTylenol
  • Mobic (meloxicam) does not kick in as fast as other NSAIDS.
  • It's available by prescription only.
  • Mobic (meloxicam) is not as safe as other alternatives for pregnant women and people who are age 60 or older.
  • It can cause serious complications like stomach bleeding and kidney problems if taken for a long time.
  • Tylenol Regular Strength (Acetaminophen) doesn't treat pain as well as other medications like ibuprofen and naproxen.
  • Drinking alcohol while taking Tylenol Regular Strength (Acetaminophen) can damage your liver.
  • To avoid hurting your liver, you need to keep track of the total amount of acetaminophen (APAP) you are taking since it's a very common ingredient in pain and cold/flu combination medicines.
  • Heavy alcohol drinkers shouldn't use Tylenol Regular Strength (Acetaminophen) since it can cause serious liver damage.
Tips from our pharmacists for people taking the medication
meloxicamTylenol
  • It should be taken only once a day, with food or milk to prevent stomach upset.
  • Mobic (meloxicam) increases the risk of stomach bleeding so tell your doctor right away if you experience any bleeding.
  • Do not take Mobic (meloxicam) with any blood thinners unless your doctor says so.
  • If you are allergic to aspirin, you may be allergic to Mobic (meloxicam) as well.
  • The capsule, suspension, and tablet forms of the medicine come in different strengths, so be careful when switching from one form to another.
  • Starts working in one hour.
  • Contains acetaminophen, also known as Tylenol or APAP. Taking too much can cause liver failure and death. Don't take more than what's recommended on the package or with other Tylenol-containing products.
  • Follow age-specific dosing instructions on how much to take. Adults should never take more than 3,000 milligrams (mg) in a single day.
  • Let your doctor know if your symptoms don't improve in a few days.
Learn more
More about meloxicamSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Mobic (meloxicam)?
Worth itNot sureNot worth it
More about TylenolSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Tylenol Regular Strength (acetaminophen)?
Worth itNot sureNot worth it