Compare Mercaptopurine vs. Asacol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

No information currently available
Treats inflammatory bowel disease.

Lialda (Mesalamine) is an effective first-line medicine for inflammatory bowel disease. There isn't a generic version and you'll have to take it multiple times a day.

Upsides
No information currently available
  • Effective first-line medication for treating and lowering the symptoms of mild inflammatory bowel disease.
  • About half the people who have mild to moderate colon inflammation and take Lialda (Mesalamine) will see improvement.
  • Available in tablets, capsules, enemas, and suppositories.
  • Certain forms of Lialda (Mesalamine) can be used during pregnancy. Talk to your doctor if you're pregnant, or plan on becoming pregnant, and you want to take Lialda (Mesalamine).
Downsides
No information currently available
  • No generic versions are available for the tablets, capsules, and suppositories (meaning it could be somewhat expensive).
  • Doesn't work well for severe colon inflammation.
  • You may need to take Lialda (Mesalamine) three or four times a day.
  • Not a good option if you have kidney disease.
Used for
  • Acute lymphoid leukemia
  • Maintenance therapy
  • As part of combination chemotherapy
Dosage forms
  • Pill
  • Liquid
  • Pill
  • Extended release
  • Enema
  • Suppository
Price
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Reviews
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Side effects
The Purinethol (Mercaptopurine) FDA package insert doesn’t have numbers about how common side effects are.
35possible side effects
  • Headache
    35%
  • Abdominal pain
    18%
  • Eructation
    16%
  • Pain
    14%
  • Nausea
    13%
  • Pharyngitis
    11%
  • Dizziness
    8%
  • Asthenia
    7%
  • Diarrhea
    7%
  • Back pain
    7%
  • Fever
    6%
  • Rash
    6%
  • Dyspepsia
    6%
  • Rhinitis
    5%
  • Arthralgia
    5%
  • Hypertonia
    5%
  • Vomiting
    5%
  • Constipation
    5%
  • Flatulence
    3%
  • Dysmenorrhea
    3%
  • Chest pain
    3%
  • Chills
    3%
  • Flu syndrome
    3%
  • Peripheral edema
    3%
  • Myalgia
    3%
  • Sweating
    3%
  • Colitis exacerbation
    3%
  • Pruritus
    3%
  • Adverse events
    3%
  • Acne
    2%
  • Increased cough
    2%
  • Malaise
    2%
  • Arthritis
    2%
  • Conjunctivitis
    2%
  • Insomnia
    2%
See more detailed side effects
Risks and risk factors
No information currently available
  • Serious allergic reactions
    • Asthma
    • Rhinitis
    • Nasal polyps
    • Aspirin allergy
    • NSAID allergy
  • Serious allergic reactions
    • Phenylketonuria (PKU)
  • Worsening kidney or liver function
    • Kidney problems
    • Liver problems
  • Blood disorders
    • Age 65 or older
  • Liver toxicity
    • Liver problems
  • Worsening of colitis
    • Taking Lialda (Mesalamine) at the start of treatment
See more detailed risks and warnings