Compare Mercaptopurine vs. Humira

Head-to-head comparisons of medication uses, side effects, ratings, and more.



Coming soon.Calms down the immune system. Humira (adalimumab) is good for treating many autoimmune conditions, but it can also cause serious side effects.
Reviews & ratings
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Have you used Purinethol (mercaptopurine)?
Worth itNot sureNot worth it
Reviews for Humira
-60% worse vs. Mercaptopurine
-51% worse vs. Mercaptopurine
+26% better vs. Mercaptopurine
182 reviews
Have you used Humira (adalimumab)?
Worth itNot sureNot worth it
Side effects

We haven’t found good data for Mercaptopurine side effects.

FDA side effect reports for Mercaptopurine »
  • Upper airway infection 4%
  • Rash 6%
  • Headache 4%
  • Sinus infection 2%
  • Nausea 1%
  • Injection site reactions 7%
  • Urinary tract infection 3%
  • Flu syndrome 1%
  • Stomach pain 3%
  • High cholesterol 2%
More Humira side effects »
How it works
Coming soon.Humira (adalimumab) is a TNF blocker which stops inflammation.
Type of medication
Prescription only
Available as
  • Pill
  • Liquid
  • Injection
Used for
  • Acute Lymphoid Leukemia
Risk factors for serious side effects
    Coming soon.
    • Taking other immunosuppressant medications such as Kineret or Orencia
    • Age 65 or older
    • Active, chronic, or recurrent infection
    • Comorbidities
    • Taking other immunosuppressant medications, such as azathiprine or 6-mercaptopurine, at the same time as Humira (adalimumab)
    Detailed Humira (adalimumab) risks & warnings »

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Upsides and benefits
    Coming soon
    • Humira (adalimumab) is effective in reducing symptoms in all of its approved indications.
    • You can give yourself Humira (adalimumab) on your own at home rather than visiting a clinic or hospital.
    • Humira (adalimumab) treats many different autoimmune conditions.
    • Available in a single-use pen (Humira Pen) that may be more convenient and easier for some people to use.
    Downsides and risks
    Coming soon
    • Not first-choice treatment for rheumatoid arthritis.
    • Humira (adalimumab) is an injection and not an oral medication.
    • Humira (adalimumab) is expensive because there's no generic available yet.
    • Humira (adalimumab) lowers your ability to fight infection and in some cases can cause serious life-threatening illness. The risk is greater if you take other drugs that lower your immune system, have an active infection, diabetes, or had tuberculosis (TB) in the past.
    • You'll need to properly dispose of the needle, syringes, or Pen in a sharps container.
    • Humira (adalimumab) needs to be refrigerated until you use it, so if you're traveling, you'll need to carry it in a cooler with an ice pack.
    Tips from our pharmacists for people taking the medication
    Coming soon
    • Humira (adalimumab) is a medication that's injected under the skin. Your doctor can give you your first dose, then you can inject yourself at home once you feel comfortable doing so on your own.
    • Humira (adalimumab) lowers your ability to fight infections, so it's important to let your doctor know if you have a fever, cough, or flu-like symptoms.
    • Tell your doctor if you have an allergy to latex since the syringe needle cover has latex in it.
    • Each time you use Humira (adalimumab), it's important to rotate the sites you chose to inject it in. Don't inject Humira (adalimumab) into skin that's red, bruised, or irritated.
    • As with all injection medicines, store securely away from children and throw away used syringes in an FDA-approved sharps disposal container, and not in the trash.
    Learn more
    More about MercaptopurineSide effectsFDA package insert
    Have you used Purinethol (mercaptopurine)?
    Worth itNot sureNot worth it
    More about HumiraSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Humira (adalimumab)?
    Worth itNot sureNot worth it