Compare Mercaptopurine vs. Sulfasalazine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

No information currently available
Reduces inflammation.

Azulfidine (Sulfasalazine) is used to treat moderate to severe inflammatory bowel conditions. It's also used with other medicines to treat rheumatoid arthritis.

Upsides
No information currently available
  • Can slow down the progression of your rheumatoid arthritis.
  • Helps control your stomach problems if you're taking it for ulcerative colitis.
Downsides
No information currently available
  • Requires constant lab monitoring, at least every other week when you first start using it.
  • Not a good option if you have kidney or liver disease.
  • If you're allergic to sulfa drugs or aspirin, you can't take Azulfidine (Sulfasalazine).
  • Can interfere with lab test results, so let your doctor know if you're taking this drug.
  • Interacts with a lot of different drugs and can also cause many side effects.
Used for
  • Acute lymphoid leukemia
  • Maintenance therapy
  • As part of combination chemotherapy
Dosage forms
  • Pill
  • Liquid
  • Pill
  • Extended release
Price
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Reviews
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Side effects
The Purinethol (Mercaptopurine) FDA package insert doesn’t have numbers about how common side effects are.
8possible side effects
  • Nausea
    19%
  • Stomach problems
    13%
  • Rash
    13%
  • Headache
    9%
  • Stomach pain
    8%
  • Vomiting
    8%
  • Fever
    5%
  • Dizziness
    4%
See more detailed side effects
Risks and risk factors
No information currently available
  • Kidney, liver, or blood problems
  • Serious skin reactions
  • Serious allergic reactions
  • Serious infections
  • Drug interactions
See more detailed risks and warnings