Compare Metaglip vs. Byetta

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Metaglip
(metformin / glipizide)

Byetta
(exenatide)

Coming soon.Lowers blood sugar. Byetta (Exenatide) can lower your blood sugars in addition to metformin. It does not increase your appetite unlike some other anti-diabetics, but must be given by injection and usually causes upset stomach.
Reviews & ratings
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Have you used Metaglip (metformin / glipizide)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Byetta (exenatide)?
Worth itNot sureNot worth it
Side effects
MetaglipByetta

We haven’t found good data for Metaglip side effects.

FDA side effect reports for Metaglip »
  • Low blood sugar 11%
  • Nausea 33%
  • Diarrhea 10%
  • Vomiting 14%
  • Headache 10%
  • Constipation 8%
  • Indigestion 5%
  • Weakness 4%
  • Abdominal swelling 3%
  • Loss of appetite 3%
More Byetta side effects »
How it works
MetaglipByetta
Coming soon.Byetta (Exenatide) enhances the release of insulin in your gut and pancreas to lower your blood sugar.
Type of medication
MetaglipByetta
Prescription only
Available as
MetaglipByetta
  • Pill
  • Injection
Used for
MetaglipByetta
  • Diabetes Mellitus Type 2
Risk factors for serious side effects
MetaglipByetta
    Coming soon.
    • Severe renal impairment
    • End-stage renal disease
    • Severe gastrointestinal disease
    • Gastroparesis
    Detailed Byetta (exenatide) risks & warnings »
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Kidneys and liver
    MetaglipByetta
    No kidneys and liver related info.
    • If you have severe kidney or liver problems, you should not take Byetta (Exenatide). Talk to your doctor about testing your kidneys before starting Byetta (Exenatide). People taking medications that are damaging to kidneys such as ACE inhibitors, NSAIDs or diuretics in addition to Byetta (Exenatide) may notice nausea, vomiting, or diarrhea.
    Pain
    MetaglipByetta
    No pain related info.
    • Using Byetta (Exenatide) has been associated with stomach pain, nausea, vomiting and diarrhea. If you have severe gastrointestinal disease such as Crohn’s Disease or Ulcerative Colitis, you should talk to your doctor about using a different medicine for diabetes. You should not use Byetta (Exenatide) if you have gastroparesis, a condition that causes slow or irregular digestion. Gastroparesis can be common for people that have had uncontrolled diabetes for a while.
    Upsides and benefits
    MetaglipByetta
    Coming soon
    • Can lower your A1c (average blood sugar over time) by 1%.
    • Not as likely to cause very low blood sugar as glyburine or insulin.
    • Does not increase your appetite like other anti-diabetic medicines.
    • Pen is dialed to a single dose for easy injections.
    Downsides and risks
    MetaglipByetta
    Coming soon
    • Byetta (Exenatide) must be injected twice a day. Other medicines like it can be injected once daily or even weekly.
    • It commonly causes nausea, vomiting, diarrhea, constipation, or indigestion.
    • Can affect how well your antibiotics and birth control pills work. Take them no sooner than one hour after your injections.
    Tips from our pharmacists for people taking the medication
    MetaglipByetta
    Coming soon
    • Inject into your belly, thighs, or upper arms within an hour of your main meals.
    • Store unused pens in the refrigerator.
    • After first use, pens can be kept at room temperature for 30 days.
    • Change the needle and prime the pen every time you inject.
    • If you're also on insulin, don't inject into the same site.
    • Best to check your blood sugar once a day to make sure your medicine is working properly.
    Learn more
    More about MetaglipSide effectsFDA package insert
    Have you used Metaglip (metformin / glipizide)?
    Worth itNot sureNot worth it
    More about ByettaSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Byetta (exenatide)?
    Worth itNot sureNot worth it