Compare Metaglip vs. Glucotrol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Metaglip
(metformin / glipizide)

Glucotrol XL
(glipizide)

Coming soon.Lowers blood sugar. Glucotrol XL (glipizide) is an effective medicine for lowering blood sugar, but it can cause your blood sugar level to be too low, so you must always carry some form of sugar with you that can be readily used.
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Coupons for Metaglip
Best available price for 60 (5mg/500mg) tablets of metaglip
Coupons for Glucotrol
Best available price for 60 (5mg) tablets of glucotrol
Reviews & ratings
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Have you used Metaglip (metformin / glipizide)?
Worth itNot sureNot worth it
Reviews for Glucotrol
50%
-50% worse vs. Metaglip
32%
-32% worse vs. Metaglip
19%
+19% better vs. Metaglip
332 reviews
Have you used Glucotrol XL (glipizide)?
Worth itNot sureNot worth it
Side effects
MetaglipGlucotrol

We haven’t found good data for Metaglip side effects.

FDA side effect reports for Metaglip »
  • Dizziness 1%
  • Diarrhea 5%
  • Nervousness 1%
  • Tremor 4%
  • Passing gas 2%
  • Low blood sugar 3%
  • Constipation 3%
  • Nausea 3%
  • Headache 2%
More Glucotrol side effects »
How it works
MetaglipGlucotrol
Coming soon.Glucotrol XL (glipizide) stimulates your body to release insulin and lower blood sugar.
Type of medication
MetaglipGlucotrol
Prescription only
Available as
MetaglipGlucotrol
  • Pill
  • Pill
  • Extended release pill
Used for
MetaglipGlucotrol
  • Diabetes Mellitus Type 2
Risk factors for serious side effects
MetaglipGlucotrol
    Coming soon.
    • Skipping meals or having inconsistent meal times
    • Drinking alcohol
    • Using other blood sugar-lowering medicine
    • People age 60 or older
    • Those with kidney and/or liver problems
    Detailed Glucotrol XL (glipizide) risks & warnings »
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Alcohol
    MetaglipGlucotrol
    No alcohol related info.
    • Avoid drinking alcohol while taking Glucotrol XL (glipizide).
    Food
    MetaglipGlucotrol
    No food related info.
    • Eat regular and well-balanced meals to keep your blood sugar levels normal.
    Kidneys and liver
    MetaglipGlucotrol
    No kidneys and liver related info.
    • People with kidney and/or liver problems take a longer time to get rid of Glucotrol XL (glipizide) from their body. They are more sensitive to the effects of low blood sugar that include symptoms such as fast heartbeat, sweating, pale skin, shakiness, confusion and irritability. They need to make sure to carry with them some form of sugar such as hard candies or glucose tablets at all times while they are on this medicine.
    • Can be used in those with kidney problems.
    Weight
    MetaglipGlucotrol
    No weight related info.
    • Can cause mild weight gain of 2 to 3 pounds on average.
    Upsides and benefits
    MetaglipGlucotrol
    Coming soon
    • Lowers A1c levels by 1-2%. (A1c is a test that measures your average blood sugars over the past 3 months).
    • Glucotrol XL (glipizide) is an oral medicine so it might be a good alternative for those who don't like injections.
    • Protects your organs and blood vessels by preventing the harmful effects of high blood sugar levels.
    • Can be used in those with kidney problems.
    • Available as a generic form and is relatively cheap.
    Downsides and risks
    MetaglipGlucotrol
    Coming soon
    • Has a higher risk than other diabetes medicine for causing blood sugar levels to be too low.
    • While taking Glucotrol XL (glipizide), your blood sugars should be checked 2 to 5 times a week, but less often once you are on a stable dose.
    • Can cause mild weight gain of 2 to 3 pounds on average.
    • Might lose its effectiveness over time.
    • Needs to be taken 30 minutes before a meal for it to be most effective.
    Tips from our pharmacists for people taking the medication
    MetaglipGlucotrol
    Coming soon
    • Take the medicine 30 minutes before eating, usually before your first big meal of the day.
    • Avoid drinking alcohol while taking Glucotrol XL (glipizide).
    • Eat regular and well-balanced meals to keep your blood sugar levels normal.
    • Check your blood sugar regularly.
    • Glucotrol XL (glipizide) can cause dizziness so avoid activities that require coordination until you know how your body can handle the medicine.
    Learn more
    More about MetaglipSide effectsFDA package insert
    Have you used Metaglip (metformin / glipizide)?
    Worth itNot sureNot worth it
    More about GlucotrolSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Glucotrol XL (glipizide)?
    Worth itNot sureNot worth it