Compare Metaglip vs. Glucovance

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Metaglip
(metformin / glipizide)

Glucovance
(metformin / glyburide)

Coming soon.Lowers blood sugar. Glucovance (Metformin / Glyburide) is a very effective combo medication to lower blood sugar when taking one medication alone isn't enough. It's likely to cause diarrhea for the first few weeks, and you can’t drink much alcohol.
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Best available price for 60 (5mg/500mg) tablets of metaglip
Reviews & ratings
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Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Metaglip (metformin / glipizide)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Glucovance (metformin / glyburide)?
Worth itNot sureNot worth it
Side effects
MetaglipGlucovance

We haven’t found good data for Metaglip side effects.

FDA side effect reports for Metaglip »
  • Upper respiratory infection 3%
  • Diarrhea 11%
  • Nausea/vomiting 2%
  • Abdominal pain 3%
  • Dizziness 2%
  • Gi side effects 8%
  • Low blood sugar 8%
More Glucovance side effects »
How it works
MetaglipGlucovance
Coming soon.Glucovance (Metformin / Glyburide) is a combination medication for diabetes. Metformin lowers sugar (glucose) production in your body, decreases the amount of glucose getting into your blood, and makes your body more sensitive to insulin. Glyburide helps your body make more insulin to lower blood sugar.
Type of medication
MetaglipGlucovance
Prescription only
Available as
MetaglipGlucovance
  • Pill
  • Pill
Used for
MetaglipGlucovance
  • Diabetes Mellitus Type 2
Risk factors for serious side effects
MetaglipGlucovance
    Coming soon.
    • Kidney problems
    • Liver problems
    • Congestive heart failure
    • Using contrast dye for procedures
    • Surgery
    Detailed Glucovance (metformin / glyburide) risks & warnings »
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Alcohol
    MetaglipGlucovance
    No alcohol related info.
    • Can't drink excessive amounts of alcohol or “binge drink” while taking this.
    • Try limiting the amount of alcohol you drink while taking this medication.
    Kidneys and liver
    MetaglipGlucovance
    No kidneys and liver related info.
    • People with poor kidney function can't use Glucovance (Metformin / Glyburide).
    • Glucovance (Metformin / Glyburide) can cause lactic acidosis, a rare but life-threatening condition. Symptoms include deep and rapid breathing, nausea, vomiting, and stomach pain. This is a medical emergency and you should get help right away. Baseline blood work for kidney and liver function are helpful to see if you can use Glucovance (Metformin / Glyburide). It may not be a good choice for people with kidney problems. Glucovance (Metformin / Glyburide) should be stopped 48 hours before and/or after surgery or procedure that'll use contrast dye.
    Weight
    MetaglipGlucovance
    No weight related info.
    • Can cause some weight gain.
    Upsides and benefits
    MetaglipGlucovance
    Coming soon
    • A combination medication that lowers your blood sugar in multiple ways. It's used by people who need tighter control of their blood sugar.
    • Can greatly lower A1c levels. The Hemoglobin A1c test measures your average blood sugar levels over the last few months.
    • Prevents harmful effects of high blood sugar levels on your organs and blood vessels.
    • Also lowers certain lipid (fat and cholesterol) levels.
    Downsides and risks
    MetaglipGlucovance
    Coming soon
    • There's a higher risk of low blood sugar episodes than with other kinds of oral diabetes medications.
    • Most people will have nausea, stomach upset, or diarrhea in the first few weeks. You can lower these symptoms if you take it on a full stomach.
    • People with poor kidney function can't use Glucovance (Metformin / Glyburide).
    • Can't drink excessive amounts of alcohol or “binge drink” while taking this.
    • Can cause some weight gain.
    Tips from our pharmacists for people taking the medication
    MetaglipGlucovance
    Coming soon
    • Can cause upset stomach, nausea, and diarrhea in the first couple of weeks.
    • Works best if you take it 30 minutes before a meal, usually your first big meal of the day.
    • Tell your doctor about any deep or rapid breathing, persistent nausea, vomiting, or stomach pain.
    • Try limiting the amount of alcohol you drink while taking this medication.
    • Check your blood sugar regularly.
    Learn more
    More about MetaglipSide effectsFDA package insert
    Have you used Metaglip (metformin / glipizide)?
    Worth itNot sureNot worth it
    More about GlucovanceSide effectsAlternativesFDA package insert
    Have you used Glucovance (metformin / glyburide)?
    Worth itNot sureNot worth it