Compare Metaglip vs. glyburide

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Metaglip
(metformin / glipizide)

Diabeta
(glyburide)

Coming soon.Lowers blood sugar. Diabeta (glyburide) is a good oral anti-diabetic medicine, but can cause hypoglycemia or low blood sugar.
Reviews & ratings
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Have you used Metaglip (metformin / glipizide)?
Worth itNot sureNot worth it
Reviews for glyburide
45%
-45% worse vs. Metaglip
34%
-34% worse vs. Metaglip
21%
+21% better vs. Metaglip
110 reviews
Have you used Diabeta (glyburide)?
Worth itNot sureNot worth it
Side effects
Metaglipglyburide

We haven’t found good data for Metaglip side effects.

FDA side effect reports for Metaglip »
  • Nausea and heartburn 2%
  • Skin allergies 2%
More glyburide side effects »
How it works
Metaglipglyburide
Coming soon.Diabeta (glyburide) stimulates your body to release insulin and lower blood sugar.
Type of medication
Metaglipglyburide
Prescription only
Available as
Metaglipglyburide
  • Pill
  • Pill
Used for
Metaglipglyburide
  • Diabetes Mellitus Type 2
Risk factors for serious side effects
Metaglipglyburide
    Coming soon.
    • Over age 65
    • Kidney problems
    • Use of other blood sugar lowering medicines
    • Alcohol
    • Intense physical activity
    Detailed Diabeta (glyburide) risks & warnings »
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Alcohol
    Metaglipglyburide
    No alcohol related info.
    • Try to avoid drinking alcohol while on Diabeta (glyburide).
    Food
    Metaglipglyburide
    No food related info.
    • Eat well-balanced meals to avoid low blood sugar.
    Kidneys and liver
    Metaglipglyburide
    No kidneys and liver related info.
    • Not ideal for elderly or those with poor kidney function.
    Weight
    Metaglipglyburide
    No weight related info.
    • Can cause weight gain, dizziness, or stomach upset.
    • Can cause weight gain (about 2 to 3 pounds).
    Upsides and benefits
    Metaglipglyburide
    Coming soon
    • Available as an oral tablet.
    • Lowers your A1c (average blood sugar over time) up to 2%.
    • Available in generic version.
    • Available in single pill combination with other anti-diabetic medicines.
    Downsides and risks
    Metaglipglyburide
    Coming soon
    • More likely to cause hypoglycemia or low blood sugar than other types of oral anti-diabetics.
    • You will have to check your blood sugar often when you first start taking it.
    • Can cause weight gain (about 2 to 3 pounds).
    • Not ideal for elderly or those with poor kidney function.
    • May not work as well for those with severe diabetes and when pancreas cannot produce insulin.
    Tips from our pharmacists for people taking the medication
    Metaglipglyburide
    Coming soon
    • Check your blood sugar regularly.
    • Eat well-balanced meals to avoid low blood sugar.
    • Works best if you take it 30 minutes before first main meal of the day.
    • Can cause weight gain, dizziness, or stomach upset.
    • Try to avoid drinking alcohol while on Diabeta (glyburide).
    Learn more
    More about MetaglipSide effectsFDA package insert
    Have you used Metaglip (metformin / glipizide)?
    Worth itNot sureNot worth it
    More about glyburideSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Diabeta (glyburide)?
    Worth itNot sureNot worth it