Compare Metaglip vs. Glyburide

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Metaglip
(Metformin / Glipizide)

Diabeta
(Glyburide)

Coming soon.Lowers blood sugar. Glyburide is a very effective oral blood sugar-lowering medicine, but has more side effects and restrictions compared to other medicines in this class (sulfonylureas).
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Reviews & ratings
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Reviews for Diabeta (Glyburide)
46%
+46% vs. Metaglip (Metformin / Glipizide)
33%
+33% vs. Metaglip (Metformin / Glipizide)
20%
20% vs. Metaglip (Metformin / Glipizide)
Side effects
MetaglipGlyburide

We haven’t found good data for Metaglip side effects.

FDA side effect reports for Metaglip »

The Glyburide FDA package insert doesn’t have numbers about how common side effects are.

More about Glyburide side effects »
How it works
MetaglipGlyburide
Coming soon.Glyburide is an anti-diabetic drug. It stimulates your body to make more insulin to lower blood sugar.
Type of medication
MetaglipGlyburide
Coming soon.
Anti-diabetic
Sulfonylurea
Prescription only
Available as
MetaglipGlyburide
  • Pill
  • Pill
Used for (click to learn more)
MetaglipGlyburide
  • Diabetes mellitus type 2
Risk factors for serious side effects
MetaglipGlyburide
Coming soon.
    • Elderly
    • Use of other blood sugar lowering medicines
    • Alcohol
    • Intense physical activity
    • History of sulfa allergies
    Detailed Diabeta (Glyburide) risks & warnings »
    Pregnancy category
    MetaglipGlyburide
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    Alcohol
    No specific alcohol-related info.
    • Avoid drinking alcohol.
    Food
    No specific food-related info.
    • Works best if you take it 30 minutes before a meal, usually your first big meal of the day.
    • Eat regular, balanced meals to avoid low blood sugar.
    Kidneys and liver
    No specific kidneys and liver-related info.
    • Not a good choice for people with kidney problems because it's processed by the kidneys.
    Sex
    No specific sex-related info.No specific sex-related info.
    Sleep
    No specific sleep-related info.No specific sleep-related info.
    Weight
    No specific weight-related info.
    • Can cause mild weight gain (2 to 3 pounds).
    • Can cause weight gain, dizziness, or stomach upset.
    Upsides and benefits
    MetaglipGlyburide
    Coming soon.
    • Oral blood sugar-lowering medicine.
    • Lowers A1c levels by 1-2%. (Hemoglobin A1c measures your average blood sugar over time.)
    • Prevents the harmful effects of high sugar levels on your organs and blood vessels.
    • One of the least expensive diabetes medicines.
    Downsides and risks
    MetaglipGlyburide
    Coming soon.
    • Higher risk of low blood sugar episodes than other kinds of oral diabetes medicines.
    • You have to check your blood sugar 2 to 5 times a week (less often once you are on a stable dose).
    • Can cause mild weight gain (2 to 3 pounds).
    • Not preferred for people 65 years or older since it can cause prolonged low blood sugar (more than 12 hours).
    • Not a good choice for people with kidney problems because it's processed by the kidneys.
    • Loses effectiveness over time or as your body stops making insulin.
    Tips from our pharmacists for people taking the medication
    MetaglipGlyburide
    Coming soon.
    • Works best if you take it 30 minutes before a meal, usually your first big meal of the day.
    • Can cause weight gain, dizziness, or stomach upset.
    • Avoid drinking alcohol.
    • Eat regular, balanced meals to avoid low blood sugar.
    • Check your blood sugar regularly.
    Learn more
    More about MetaglipSide effectsFDA package insert
    More about GlyburideSide effectsReviews & ratingsAlternativesFDA package insert