Compare Metaglip vs. Januvia

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Metaglip
(metformin / glipizide)

Januvia
(sitagliptin)

Coming soon.Lowers your blood sugar. Januvia (sitagliptin) is a good add-on treatment if your blood sugars are not controlled and you don't want to use an injectable medicine.
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Coupons for Metaglip
Best available price for 60 (5mg/500mg) tablets of metaglip
Coupons for Januvia
Best available price for 30 (100mg) tablets of januvia
Reviews & ratings
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Have you used Metaglip (metformin / glipizide)?
Worth itNot sureNot worth it
Reviews for Januvia
44%
-44% worse vs. Metaglip
34%
-34% worse vs. Metaglip
17%
+17% better vs. Metaglip
143 reviews
Have you used Januvia (sitagliptin)?
Worth itNot sureNot worth it
Side effects
MetaglipJanuvia

We haven’t found good data for Metaglip side effects.

FDA side effect reports for Metaglip »
  • Common cold 2%
  • Diarrhea 1%
  • Upper respiratory infection 3%
  • Headache 1%
More Januvia side effects »
How it works
MetaglipJanuvia
Coming soon.Januvia (sitagliptin) is an anti-diabetic drug that enhances your body's release of insulin.
Type of medication
MetaglipJanuvia
Prescription only
Available as
MetaglipJanuvia
  • Pill
  • Pill
Used for
MetaglipJanuvia
  • Diabetes Mellitus Type 2
Risk factors for serious side effects
MetaglipJanuvia
    Coming soon.
    • History of pancreatitis
    • High blood triglyceride levels
    • Gallstones (stones in gallbladder)
    • History of alchoholism
    • Kidney problems
    Detailed Januvia (sitagliptin) risks & warnings »
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Food
    MetaglipJanuvia
    No food related info.
    • Take once a day in the morning with or without food.
    Kidneys and liver
    MetaglipJanuvia
    No kidneys and liver related info.
    • Januvia (sitagliptin) can worsen kidney problems. Your doctor may check your kidney function before and during treatment. Your doctor may have to adjust the dose or stop this medicine based on changes in kidney function.
    Pain
    MetaglipJanuvia
    No pain related info.
    • Tell your doctor right away if you have severe stomach pain, nausea, and/or vomiting. These are symptoms of pancreatitis.
    Weight
    MetaglipJanuvia
    No weight related info.
    • It is less likely to cause weight gain and low blood sugar compared to other diabetes medicines.
    Upsides and benefits
    MetaglipJanuvia
    Coming soon
    • Oral blood sugar-lowering medicine.
    • Januvia (sitagliptin) is not linked to worsening heart failure like other medicines in its class.
    • Uses the hormones naturally produced by your body to affect how sugar is processed.
    • It is less likely to cause weight gain and low blood sugar compared to other diabetes medicines.
    Downsides and risks
    MetaglipJanuvia
    Coming soon
    • Lowers A1c (average blood sugar over time) by less than 1%.
    • Available as brand version only.
    • Some people might get frequent cold-like symptoms.
    • Rare but serious side effects include pancreatitis and severe joint pain.
    Tips from our pharmacists for people taking the medication
    MetaglipJanuvia
    Coming soon
    • Take once a day in the morning with or without food.
    • Can cause headache and cold-like symptoms.
    • Tell your doctor right away if you have severe stomach pain, nausea, and/or vomiting. These are symptoms of pancreatitis.
    • Tell your doctor right away if you are experiencing severe joint pain.
    • Check your blood sugar regularly to check for low blood sugar.
    Learn more
    More about MetaglipSide effectsFDA package insert
    Have you used Metaglip (metformin / glipizide)?
    Worth itNot sureNot worth it
    More about JanuviaSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Januvia (sitagliptin)?
    Worth itNot sureNot worth it