Compare Methyltestosterone vs. Axiron

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Treats low testosterone.

Android (Methyltestosterone) is an oral form of testosterone that's easy to take but not available as a generic yet.

Treats low testosterone.

This testosterone topical solution is a convenient topical form of hormone replacement that's less likely to rub off on other people you come into contact with, but it's not available as a generic yet.

Upsides
  • A first-choice treatment for men with low testosterone.
  • Oral form of testosterone that some people prefer over injections and topical gels and patches.
  • You're less likely with this formulation to transfer testosterone topical solution to another person since this is applied to the armpits -- unlike some other forms of topical testosterone.
  • You can use your regular deodorant or antiperspirant, but just make sure to apply that first before using testosterone topical solution.
Downsides
  • Not a first-choice treatment for breast cancers that respond to testosterone.
  • Not available as generic, so it can be expensive.
  • Only available as brand name.
  • You have to wait at least 2 hours after applying testosterone topical solution before you can swim or bathe, otherwise your body won't absorb the entire amount.
Used for
  • Low testosterone
  • Delayed puberty
  • Metastatic breast cancer
  • Low testosterone
Dosage forms
  • Pill
  • Topical
Price
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Reviews
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Side effects
The Android (Methyltestosterone) FDA package insert doesn’t have numbers about how common side effects are.
7possible side effects
  • Application Site Irritation
    8%
  • Application Site Erythema
    7%
  • Hematocrit Increased
    7%
  • Headache
    6%
  • Diarrhea
    4%
  • Vomiting
    4%
  • PSA Increased
    4%
See more detailed side effects
Risks and risk factors
  • Breast tissue changes
    • Male
  • Changes in sex drive
    • Male
  • Inability to urinate
    • Enlarged prostate (benign prostatic hypertrophy)
  • Changes in sperm
    • Taking high doses of Android (Methyltestosterone)
  • Swelling in the legs
    • Heart, liver or kidney disease
  • Virilization
    • Female
  • High calcium in the blood
    • Breast cancer
    • Inability to move
  • Liver disease
  • Changes in mood
  • Changes in blood sugar
    • Diabetes
  • Changes in blood thinning
    • On blood thinners
  • Blood clots
See more detailed risks and warnings
No information currently available