Compare Methyltestosterone vs. Depo-Testosterone

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Treats low testosterone.

Android (Methyltestosterone) is an oral form of testosterone that's easy to take but not available as a generic yet.

Treats low testosterone.

This testosterone injection only has to be given once or twice a month and you can do it at home, but someone has to help you inject.

3.0/ 5 average rating with 100 reviewsforDepo-Testosterone
Upsides
  • A first-choice treatment for men with low testosterone.
  • Oral form of testosterone that some people prefer over injections and topical gels and patches.
  • A first-choice treatment for low testosterone in men and delayed puberty in boys.
  • Available in generic.
  • Only has to be given once every 2 to 4 weeks.
  • The shot can be done at home.
Downsides
  • Not a first-choice treatment for breast cancers that respond to testosterone.
  • Not available as generic, so it can be expensive.
  • Only available as a shot.
  • Has to be given by someone else since it has to be injected into your buttocks.
Used for
  • Low testosterone
  • Delayed puberty
  • Metastatic breast cancer
  • Low testosterone
Dosage forms
  • Pill
  • Injection
Price
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Reviews
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100 reviews so far
49%
saidit'sworth it
32%
saiditworked well
17%
saidit'sa big hassle

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Side effects
The Android (Methyltestosterone) FDA package insert doesn’t have numbers about how common side effects are.
The Depo-Testosterone (Testosterone Cypionate Injection) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Breast tissue changes
    • Male
  • Changes in sex drive
    • Male
  • Inability to urinate
    • Enlarged prostate (benign prostatic hypertrophy)
  • Changes in sperm
    • Taking high doses of Android (Methyltestosterone)
  • Swelling in the legs
    • Heart, liver or kidney disease
  • Virilization
    • Female
  • High calcium in the blood
    • Breast cancer
    • Inability to move
  • Liver disease
  • Changes in mood
  • Changes in blood sugar
    • Diabetes
  • Changes in blood thinning
    • On blood thinners
  • Blood clots
See more detailed risks and warnings
  • Breast tissue changes
    • Male
  • Changes in sex drive
    • Male
  • Inability to urinate
    • Enlarged prostate (benign prostatic hypertrophy)
  • Changes in sperm
    • Taking high doses of Depo-Testosterone (Testosterone Cypionate Injection)
  • Swelling in the legs
    • Heart, liver or kidney disease
  • High calcium in the blood
    • Inability to move
    • Cancer
  • Liver disease
  • Changes in mood
  • Changes in blood sugar
    • Diabetes
  • Changes in blood thinning
    • On blood thinners
  • Blood clots
See more detailed risks and warnings