Compare Miralax vs. Senna-S

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Miralax
(Polyethylene Glycol)

Senna-S
(Docusate / Senna)

Helps get things moving. Miralax (Polyethylene Glycol) provides effective relief of constipation without "cramping" your style.Helps get things moving and softens things up. Senna and docusate join forces to create Senna-S (Docusate / Senna), a vegetable-based laxative that gently relieves constipation.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
5.427272727272728Miralax
Reviews for Miralax (Polyethylene Glycol)
74%
of people say Miralax (Polyethylene Glycol) is worth it
54%
say it works well
10%
say it's a big hassle
Reviews for Senna-S (Docusate / Senna)
38%
36% vs. Miralax (Polyethylene Glycol)
29%
25% vs. Miralax (Polyethylene Glycol)
21%
11% vs. Miralax (Polyethylene Glycol)
Side effects
MiralaxSenna-S

The Miralax FDA package insert doesn’t have numbers about how common side effects are.

More about Miralax side effects »

We haven’t found good data for Senna-S side effects.

FDA side effect reports for Senna-S »
How it works
MiralaxSenna-S
Miralax (Polyethylene Glycol) is an osmotic laxative. It uses osmosis to keep more water in your intestine, which softens your stool and makes it easier to pass.Senna-S (Docusate / Senna) is a combination medicine. Docusate is a stool softener, and Senna is a stimulant laxative. These two ingredients work together to make stools easier to pass.
Type of medication
MiralaxSenna-S
Laxative
Osmotic
Over-the-counter
Laxative
Stool softener
Laxative
Stimulant
Over-the-counter
Available as
MiralaxSenna-S
  • Liquid
  • Pill
Used for (click to learn more)
MiralaxSenna-S
Risk factors for serious side effects
MiralaxSenna-S
  • Taking with medications that cause electrolyte imbalance
  • Age 60 or older
  • Women of childbearing age
  • Age 60 or older
  • Malignancy
  • Other condition that causes blockage or narrowing of bowel
  • Taking medications that cause constipation
Detailed Miralax (Polyethylene Glycol) risks & warnings »
  • Age 60 or older
  • Malignancy
  • Other condition that causes blockage or narrowing of bowel
  • Taking medications that cause constipation
  • Age 60 or older
  • Taking medications that cause constipation
  • People who can't walk or move well (immobility)
  • Women of childbearing age
  • Allergy or sensitivity to aloe (cross-allergic reaction)
Detailed Senna-S (Docusate / Senna) risks & warnings »
Pregnancy category
MiralaxSenna-S
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
NFDA pregnancy category (Unknown)

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

See the FDA package insert
Alcohol
No specific alcohol-related info.No specific alcohol-related info.
Food
  • Talk to you doctor about eating certain foods and getting more exercise to help prevent your constipation.
  • Talk to you doctor about eating certain foods and getting more exercise to help prevent your constipation.
Kidneys and liver
  • Ask your doctor before you take Miralax if you have nausea or vomiting, irritable bowel syndrome (IBS), kidney disease, or sudden changes in your stool for more than 2 weeks.
No specific kidneys and liver-related info.
Sex
No specific sex-related info.No specific sex-related info.
Sleep
No specific sleep-related info.No specific sleep-related info.
Weight
No specific weight-related info.No specific weight-related info.
Upsides and benefits
MiralaxSenna-S
  • Miralax is the most recommended laxative by pharmacists and doctors.
  • Most people felt it was worth the hassle.
  • It's gluten and sugar free.
  • It causes little to no cramping, bloating, gas, or feelings like you "have to go right now" compared to some other medicines to treat constipation.
  • Works differently than other over-the-counter laxatives so it's a great alternative if other medicines haven't worked.
  • The combination of a laxative and stool softener might work better for people with constipation caused by medicines.
  • The laxative in Docusate/Senna was used over 3,500 years ago, so it's been around for a while.
  • Docusate/Senna is clinically proven to relieve constipation from a variety of causes.
  • One of the few laxative/stool-softener combinations that can be given to children 2 and older.
  • It may not work for everyone, but people felt it was worth the hassle.
Downsides and risks
MiralaxSenna-S
  • You have to dissolve Miralax in a beverage and drink it versus taking a pill.
  • It's not for children 16 years or younger.
  • Miralax doesn't work overnight. It can take up to 2-4 days to have a bowel movement.
  • It's not recommended that you take it for more than a week, so it you haven't had any success, you'll need to call your doctor for other laxative options.
  • Most people felt that it's not the most effective laxative out there, but they could deal with the hassle and it worked pretty well.
  • Docusate/Senna can cause cramping or the feeling that you "have to go right now".
Tips from our pharmacists for people taking the medication
MiralaxSenna-S
  • Dissolve Miralax powder in 4 to 8 ounces of water, juice or other drink (cold or hot) once a day.
  • Works in about 1 to 3 days. Don't use for more than 1 week.
  • Miralax is available in four different size dose bottles. It also come in pre-measured single-dose packets to make dosing easier or if you travel.
  • Ask your doctor about giving it to anyone younger than 17 years.
  • Doesn't cause as much bloating, cramping or feelings like you "have to go right now" as other medicines to treat constipation.
  • Ask your doctor before you take Miralax if you have nausea or vomiting, irritable bowel syndrome (IBS), kidney disease, or sudden changes in your stool for more than 2 weeks.
  • Stop using Miralax and call your doctor if you have pain, cramping, swelling or bulging in your belly, diarrhea, rectal bleeding or find you need to use for more than 1 week.
  • Talk to you doctor about eating certain foods and getting more exercise to help prevent your constipation.
  • Docusate/Senna is a combination of a laxative and stool softener. Together they work to relieve constipation better than each medicine alone.
  • Best to take at bedtime or as your doctor has prescribed, but not for more than one week. It works in about 6-12 hours.
  • Ask your doctor about giving Docusate/Senna to anyone younger than 2 years.
  • Don't use if you're taking mineral oil for constipation. Ask your doctor first.
  • Ask your doctor before taking Docusate/Senna if you have stomach pain, nausea, vomiting or had sudden changes in your stool for more than 2 weeks.
  • Check with your baby doctor before using or if you're pregnant or breastfeeding.
  • Talk to you doctor about eating certain foods and getting more exercise to help prevent your constipation.
Learn more
More about MiralaxSide effectsReviews & ratingsAlternativesFDA package insert
More about Senna-SSide effectsReviews & ratingsAlternativesFDA package insert