Compare Mirapex vs. carbidopa

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Mirapex
(pramipexole)

Lodosyn
(carbidopa)

Helps with movement problems. Mirapex (Pramipexole) is an effective medicine for Parkinson's disease or restless leg syndrome, but there are potentially serious side effects.Treats Parkinson's disease when given with levodopa. Lodosyn (carbidopa) enhances the effect of levodopa. It cannot relieve symptoms of Parkinson's disease when taken by itself.
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Prices and coupon for 30 (0.25mg) tablets of pramipexole
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Prices and coupon for 90 (25mg) tablets of carbidopa
Reviews & ratings
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Have you used Mirapex (pramipexole)?
Worth itNot sureNot worth it

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Have you used Lodosyn (carbidopa)?
Worth itNot sureNot worth it
Side effects
Mirapexcarbidopa
  • Nausea 14%
  • Flu 3%
  • Nasal congestion 2%
  • Pain in extremity 2%
  • Any side effect 1%
  • Hallucinations 3%
  • Dizziness 1%
  • Drowsiness 2%
More Mirapex side effects »

We haven’t found good data for carbidopa side effects.

FDA side effect reports for carbidopa »
How it works
Mirapexcarbidopa
Mirapex (Pramipexole) is a dopamine agonist. It binds to receptors in the brain and helps improve movement in people with Parkinson's disease or restless leg syndrome.Lodosyn (carbidopa) is a decarboxylase inhibitor that allows levodopa to enter the brain and relieve symptoms of Parkinson's disease.
Type of medication
Mirapexcarbidopa
Prescription only
Prescription only
Available as
Mirapexcarbidopa
  • Pill
  • Extended release
  • Pill
Used for
Mirapexcarbidopa
Risk factors for serious side effects
Mirapexcarbidopa
    • Taking with alcohol
    • Taking other medicines that make you less alert
    • Taking blood pressure-lowering medicines
    • Current kidney problems
    • Parkinson's disease
    • Age 65 years or older
    Detailed Mirapex (pramipexole) risks & warnings »
      Detailed Lodosyn (carbidopa) risks & warnings »
      Pregnancy

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Food
      Mirapexcarbidopa
      • Take Mirapex (Pramipexole) with food if it makes you feel nauseous.
      No food related info.
      Kidneys and liver
      Mirapexcarbidopa
      • Not the best choice if you have kidney problems. Your doctor may have to adjust your dose based on your kidney function.
      • Mirapex (Pramipexole) is processed by the kidney. If you have kidney problems, talk to your doctor because you may need a different dose.
      No kidneys and liver related info.
      Upsides and benefits
      Mirapexcarbidopa
      • In studies, Mirapex (Pramipexole) when taken by itself or with other medicines, was effective in lowering movement fluctuations for people with Parkinson's disease.
      • Mirapex (Pramipexole) is sometimes preferred over other medicines that treat Parkinson's disease in older people since it causes fewer movement and mental fluctuations.
      • Is effective for treating restless leg syndrome.
      • Available in a short-acting and a long-acting form.
      • Extra doses of Lodosyn (carbidopa) allows you to get more out of levodopa, especially in later stages of the disease.
      • It is available in a combination pill with levodopa once you find the right dose that works for you.
      Downsides and risks
      Mirapexcarbidopa
      • Mirapex (Pramipexole) isn't a first-choice treatment for Parkinson's disease. It can be used by itself, but it's usually used with other medicines.
      • Mirapex (Pramipexole) can cause hallucinations in older people.
      • Not the best choice if you have kidney problems. Your doctor may have to adjust your dose based on your kidney function.
      • You can't suddenly stop taking Mirapex (Pramipexole). You'll have to slowly lower your dose, especially if you've been using it for a long time.
      • Your doctor may need to change the dose of Lodosyn (carbidopa) frequently before finding the right dose.
      Tips from our pharmacists for people taking the medication
      Mirapexcarbidopa
      • You should start Mirapex (Pramipexole) at a low dose and your doctor will raise the dose slowly. This will help lower your risk of side effects, such as drowsiness and low blood pressure.
      • Can cause intense urges and compulsive behaviors that are hard to control, such as binge eating, gambling, and sexual urges. Talk to your doctor right away if you have any of these feelings.
      • You can suddenly fall asleep without warning while on this medicine. Don't perform any tasks that require mental alertness, like driving, or drinking alcohol until you know how Mirapex (Pramipexole) affects you. Let your doctor know if you have a history of sleep problems.
      • Take Mirapex (Pramipexole) 2 to 3 hours before bedtime for restless leg syndrome.
      • Take Mirapex (Pramipexole) with food if it makes you feel nauseous.
      • Lodosyn (carbidopa) can make you very sleepy. Don't drive or do anything that requires concentration until you know how your body reacts to it.
      • Your saliva, sweat and urine may have dark color and stain your clothing while taking Lodosyn (carbidopa).
      • Take Lodosyn (carbidopa) 30-60 minutes before a meal so that your body can properly absorb it. Don't eat too much high protein foods (meat, milk, cheese or nuts) because doing so can prevent it from getting absorbed into your body.
      • Lodosyn (carbidopa) doesn't work when taken by itself. Don't stop taking your other medicines for Parkinson's disease.
      • Lodosyn (carbidopa) may cause unusual cravings in some people.
      Learn more
      More about MirapexSide effectsReviews & ratingsAlternativesFDA package insert
      Have you used Mirapex (pramipexole)?
      Worth itNot sureNot worth it
      More about carbidopaSide effectsAlternativesFDA package insert
      Have you used Lodosyn (carbidopa)?
      Worth itNot sureNot worth it