Compare Mirapex vs. carbidopa / levodopa extended release

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Mirapex (Pramipexole)

Prescription only
Helps with movement problems.

Mirapex (Pramipexole) is an effective medicine for Parkinson's disease or restless leg syndrome, but there are potentially serious side effects.

Treats Parkinson's disease.

Sinemet CR (carbidopa / levodopa extended release) is the first choice treatment for Parkinson's disease.

Upsides
  • In studies, Mirapex (Pramipexole) when taken by itself or with other medicines, was effective in lowering movement fluctuations for people with Parkinson's disease.
  • Mirapex (Pramipexole) is sometimes preferred over other medicines that treat Parkinson's disease in older people since it causes fewer movement and mental fluctuations.
  • Is effective for treating restless leg syndrome.
  • Available in a short-acting and a long-acting form.
  • Sinemet CR (carbidopa / levodopa extended release) is released over a long period of time in your body and can allow you to take fewer pills less frequently.
Downsides
  • Mirapex (Pramipexole) isn't a first-choice treatment for Parkinson's disease. It can be used by itself, but it's usually used with other medicines.
  • Mirapex (Pramipexole) can cause hallucinations in older people.
  • Not the best choice if you have kidney problems. Your doctor may have to adjust your dose based on your kidney function.
  • You can't suddenly stop taking Mirapex (Pramipexole). You'll have to slowly lower your dose, especially if you've been using it for a long time.
  • Sinemet CR (carbidopa / levodopa extended release) can make you very sleepy. Don't drive or do anything that requires concentration until you know how your body reacts to it.
  • Your saliva, sweat and urine may have dark color and stain your clothing while taking Sinemet CR (carbidopa / levodopa extended release).
  • Sinemet CR (carbidopa / levodopa extended release) will lose its effect over time. If you notice it wearing off sooner than you'd like, talk to your doctor.
  • Sinemet CR (carbidopa / levodopa extended release) may cause unusual cravings in some people.
Used for
Dosage forms
  • Pill
  • Extended release
  • Extended release
Price
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$9.26
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Lowest price near you
$90.2
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Reviews
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Side effects
8possible side effects
  • Postural hypotension
    53%
  • Dyskinesia
    47%
  • Extrapyramidal syndrome
    28%
  • Insomnia
    27%
  • Dizziness
    26%
  • Accidental injury
    17%
  • Hallucinations
    17%
  • Any side effect
    12%
See more detailed side effects
10possible side effects
  • Difficulty controlling movements
    17%
  • Nausea
    6%
  • Hallucinations
    4%
  • Confusion
    4%
  • Dizziness
    3%
  • Depression
    2%
  • Urinary tract infection
    2%
  • Headache
    2%
  • Unusual dreams
    2%
  • Muscle spasms
    2%
See more detailed side effects
Risks and warnings
  • Driving impairment

    Taking with alcohol

    ...and 1 more risk factors

  • Low blood pressure

    Taking blood pressure-lowering medicines

  • Worsening kidney function

    Current kidney problems

  • Skin cancer

    Parkinson's disease

  • Hallucinations

    Age 65 years or older

See more detailed risks and warnings
  • Falling asleep during the day

    Taking other medicines for Parkinson's

  • High fever and confusion

    Stopping Sinemet CR (carbidopa / levodopa extended release) suddenly

  • Lack of impulse control

    Taking other medicines for Parkinson's disease

See more detailed risks and warnings