Compare Mirapex vs. Eldepryl

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Mirapex (Pramipexole)

Prescription only

Eldepryl (selegiline)

Prescription only
Helps with movement problems.

Mirapex (Pramipexole) is an effective medicine for Parkinson's disease or restless leg syndrome, but there are potentially serious side effects.

Treats Parkinson's disease.

Used with other medicines for Parkinson's disease to boost its effect.

Upsides
  • In studies, Mirapex (Pramipexole) when taken by itself or with other medicines, was effective in lowering movement fluctuations for people with Parkinson's disease.
  • Mirapex (Pramipexole) is sometimes preferred over other medicines that treat Parkinson's disease in older people since it causes fewer movement and mental fluctuations.
  • Is effective for treating restless leg syndrome.
  • Available in a short-acting and a long-acting form.
  • There are two different versions of Eldepryl (selegiline), a quick dissolving tablet and a regular tablet.
  • Eldepryl (selegiline) is one of the recommended medicines you can take along with carbidopa/levodopa if your Parkinson's disease is getting worse.
Downsides
  • Mirapex (Pramipexole) isn't a first-choice treatment for Parkinson's disease. It can be used by itself, but it's usually used with other medicines.
  • Mirapex (Pramipexole) can cause hallucinations in older people.
  • Not the best choice if you have kidney problems. Your doctor may have to adjust your dose based on your kidney function.
  • You can't suddenly stop taking Mirapex (Pramipexole). You'll have to slowly lower your dose, especially if you've been using it for a long time.
  • You may have to limit the amount of cheese, smoked meat, and soy sauce you eat while taking Eldepryl (selegiline) since it can raise your blood pressure.
  • Can keep you up at night if you take it later in the day
  • Doesn't work by itself to treat Parkinson's disease.
Used for
Dosage forms
  • Pill
  • Extended release
  • Pill
  • Dissolving tablet
Price
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$9.26
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$25.69
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Reviews
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Side effects
8possible side effects
  • Postural hypotension
    53%
  • Dyskinesia
    47%
  • Extrapyramidal syndrome
    28%
  • Insomnia
    27%
  • Dizziness
    26%
  • Accidental injury
    17%
  • Hallucinations
    17%
  • Any side effect
    12%
See more detailed side effects
10possible side effects
  • Skin irritation at the patch
    24%
  • Headache
    18%
  • Insomnia
    12%
  • Diarrhea
    9%
  • Dry mouth
    8%
  • Weight loss of at least 5%
    5%
  • Indigestion
    4%
  • Rash
    4%
  • Sore throat
    3%
  • Sinus infection
    3%
See more detailed side effects
Risks and warnings
  • Driving impairment

    Taking with alcohol

    ...and 1 more risk factors

  • Low blood pressure

    Taking blood pressure-lowering medicines

  • Worsening kidney function

    Current kidney problems

  • Skin cancer

    Parkinson's disease

  • Hallucinations

    Age 65 years or older

See more detailed risks and warnings
  • Increased blood pressure

    Eating foods rich in tyramine, like soy sauce, fermented cheese and smoked meats

    ...and 1 more risk factors

  • Serotonin syndrome

    Tricyclic antidepressants

    ...and 5 more risk factors

  • Falling asleep during the day

    Taking other medicines for Parkinson's

See more detailed risks and warnings