Compare Mirapex vs. Requip

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Mirapex
(Pramipexole)

Requip
(Ropinirole)

Helps with movement problems. Mirapex (Pramipexole) is an effective medicine for Parkinson's disease or restless leg syndrome, but there are potentially serious side effects.Helps with movement problems. Requip (Ropinirole) is an effective medicine for Parkinson's disease or restless leg syndrome, but there are potentially serious side effects.
Reviews & ratings
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Have you used Mirapex (Pramipexole)?
Worth itNot sureNot worth it

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Have you used Requip (Ropinirole)?
Worth itNot sureNot worth it
Side effects
MirapexRequip
  • Dizziness 1%
  • Somnolence 2%
  • Nausea 2%
  • Hallucinations 3%
  • Any side effect 1%
  • Malaise 1%
  • Dysphagia 2%
  • Decreased weight 2%
  • Dystonia 1%
More Mirapex side effects »
  • Dry mouth 2%
  • Fall/injury 1%
  • Anxiety 1%
  • Hypotension 2%
  • Dysphagia 1%
  • Flatulence 1%
  • Increased saliva 1%
  • Weight decrease 1%
  • Anemia 2%
  • Pyuria 1%
More Requip side effects »
How it works
MirapexRequip
Mirapex (Pramipexole) is a dopamine agonist. It binds to receptors in the brain and helps improve movement in people with Parkinson's disease or restless leg syndrome.Requip (Ropinirole) is a dopamine agonist. It binds to receptors in the brain and helps improve movement in people with Parkinson's disease or restless leg syndrome.
Type of medication
MirapexRequip
Prescription onlyLower-cost generic availablePrescription onlyLower-cost generic available
Available as
MirapexRequip
  • Pill
  • Extended release
  • Pill
  • Extended release
Used for
MirapexRequip
Risk factors for serious side effects
MirapexRequip
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • Taking blood pressure-lowering medicines
  • Current kidney problems
  • Parkinson's disease
Detailed Mirapex (Pramipexole) risks & warnings »
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • Taking blood pressure-lowering medicines
  • Current kidney problems
  • Parkinson's disease
Detailed Requip (Ropinirole) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Food
MirapexRequip
  • Take Mirapex (Pramipexole) with food if it makes you feel nauseous.
  • Take Requip (Ropinirole) with food if it makes you feel nauseous.
Kidneys and liver
MirapexRequip
  • Mirapex (Pramipexole) is processed by the kidney. If you have kidney problems, talk to your doctor because you may need a different dose.
  • Not the best choice if you have kidney problems. Your doctor may have to adjust your dose based on your kidney function.
  • Requip (Ropinirole) is processed by the kidney. If you have kidney problems, talk to your doctor because you may need a different dose.
  • Not the best choice if you have kidney problems. Your doctor may have to adjust your dose based on your kidney function.
Upsides and benefits
MirapexRequip
  • In studies, Mirapex (Pramipexole) when taken by itself or with other medicines, was effective in lowering movement fluctuations for people with Parkinson's disease.
  • Mirapex (Pramipexole) is sometimes preferred over other medicines that treat Parkinson's disease in older people since it causes fewer movement and mental fluctuations.
  • Is effective for treating restless leg syndrome.
  • Available in a short-acting and a long-acting form.
  • In studies, Requip (Ropinirole) when taken by itself or with other medicines, was effective in lowering movement fluctuations for people with Parkinson's disease.
  • Requip (Ropinirole) is sometimes preferred over other medicines that treat Parkinson's disease in older people since it causes fewer movement and mental fluctuations.
  • Is effective for treating restless leg syndrome.
  • Available in a short-acting and a long-acting form.
Downsides and risks
MirapexRequip
  • Mirapex (Pramipexole) isn't a first-choice treatment for Parkinson's disease. It can be used by itself, but it's usually used with other medicines.
  • Mirapex (Pramipexole) can cause hallucinations in older people.
  • Not the best choice if you have kidney problems. Your doctor may have to adjust your dose based on your kidney function.
  • You can't suddenly stop taking Mirapex (Pramipexole). You'll have to slowly lower your dose, especially if you've been using it for a long time.
  • Requip (Ropinirole) isn't a first-choice treatment for Parkinson's disease. It can be used by itself, but it's usually used with other medicines.
  • Requip (Ropinirole) can cause hallucinations in older people.
  • Not the best choice if you have kidney problems. Your doctor may have to adjust your dose based on your kidney function.
  • You can't suddenly stop taking Requip (Ropinirole). You'll have to slowly lower your dose, especially if you've been using it for a long time.
Tips from our pharmacists for people taking the medication
MirapexRequip
  • You should start Mirapex (Pramipexole) at a low dose and your doctor will raise the dose slowly. This will help lower your risk of side effects, such as drowsiness and low blood pressure.
  • Can cause intense urges and compulsive behaviors that are hard to control, such as binge eating, gambling, and sexual urges. Talk to your doctor right away if you have any of these feelings.
  • You can suddenly fall asleep without warning while on this medicine. Don't perform any tasks that require mental alertness, like driving, or drinking alcohol until you know how Mirapex (Pramipexole) affects you. Let your doctor know if you have a history of sleep problems.
  • Take Mirapex (Pramipexole) 2 to 3 hours before bedtime for restless leg syndrome.
  • Take Mirapex (Pramipexole) with food if it makes you feel nauseous.
  • You should start Requip (Ropinirole) at a low dose and your doctor will raise the dose slowly. This will help lower your risk of side effects, such as drowsiness and low blood pressure.
  • Can cause intense urges and compulsive behaviors that are hard to control, such as binge eating, gambling, and sexual urges. Talk to your doctor right away if you have any of these feelings.
  • You can suddenly fall asleep without warning while on this medicine. Don't perform any tasks that require mental alertness, like driving, or drinking alcohol until you know how Requip (Ropinirole) affects you. Let your doctor know if you have a history of sleep problems.
  • Take Requip (Ropinirole) 2 to 3 hours before bedtime for restless leg syndrome.
  • Take Requip (Ropinirole) with food if it makes you feel nauseous.
Learn more
More about MirapexSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Mirapex (Pramipexole)?
Worth itNot sureNot worth it
More about RequipSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Requip (Ropinirole)?
Worth itNot sureNot worth it