Compare Monopril vs. Lisinopril

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Monopril
(fosinopril)

Zestril
(lisinopril)

Coming soon.Lowers blood pressure. Zestril (lisinopril) is a good blood pressure-lowering medicine that protects kidney function.
Reviews & ratings
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Have you used Monopril (fosinopril)?
Worth itNot sureNot worth it
Reviews for Lisinopril
61%
-61% worse vs. Monopril
51%
-51% worse vs. Monopril
14%
+14% better vs. Monopril
687 reviews
Have you used Zestril (lisinopril)?
Worth itNot sureNot worth it
Side effects
MonoprilLisinopril

We haven’t found good data for Monopril side effects.

FDA side effect reports for Monopril »
  • Headache 4%
  • Dizziness 4%
  • Cough 3%
  • Low blood pressure 4%
  • Chest pain 2%
  • Kidney damage 10%
  • Fainting 7%
  • High potassium 6%
More Lisinopril side effects »
How it works
MonoprilLisinopril
Coming soon.Zestril (lisinopril) is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.
Type of medication
MonoprilLisinopril
Prescription only
Available as
MonoprilLisinopril
  • Pill
  • Pill
  • Liquid
Used for
MonoprilLisinopril
  • Hypertension Heart Failure
Risk factors for serious side effects
MonoprilLisinopril
    Coming soon.
    • Women of childbearing age
    • African descent
    • Current kidney problems
    • Medicines that increase potassium
    • Use of salt substitutes
    Detailed Zestril (lisinopril) risks & warnings »
    Pregnancy

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Kidneys and liver
    MonoprilLisinopril
    No kidneys and liver related info.
    • You'll need to have blood tests done to check your kidney function.
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    Upsides and benefits
    MonoprilLisinopril
    Coming soon
    • A first-choice blood pressure treatment for many people.
    • Lowers the risk of heart attack and stroke.
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
    • Very cheap drug, and comes available as a liquid for children over 6 years of age.
    Downsides and risks
    MonoprilLisinopril
    Coming soon
    • Up to 10% of people can get a dry cough while using this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
    • Requires a yearly blood test to see how the medicine is affecting your body.
    • Zestril (lisinopril) isn't safe to use if you're pregnant.
    • Doesn't work as well in people of African descent, and can cause a greater chance of face, tongue, or lip swelling.
    Tips from our pharmacists for people taking the medication
    MonoprilLisinopril
    Coming soon
    • Can cause dizziness the first few days you're taking it.
    • Check your blood pressure about 1 week after starting Zestril (lisinopril), and tell your doctor if it hasn't improved.
    • Let your doctor know about any dizziness, tiredness, cough, or throat irritation that doesn't go away.
    • You'll need to have blood tests done to check your kidney function.
    • Don't take Zestril (lisinopril) if you're pregnant.
    Learn more
    More about MonoprilSide effectsFDA package insert
    Have you used Monopril (fosinopril)?
    Worth itNot sureNot worth it
    More about LisinoprilSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Zestril (lisinopril)?
    Worth itNot sureNot worth it