Compare Mucinex D vs. Robitussin DM

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Mucinex D
(Guaifenesin / Pseudoephedrine)

Robitussin Dm
(Guaifenesin / Dextromethorphan)

Breaks up mucus and relieves congestion. Mucinex D (Guaifenesin / Pseudoephedrine) is good if you have a stuffy nose and a cough with mucus, but it could keep you up at night.Breaks up mucus and relieves cough. Robitussin Dm (Guaifenesin / Dextromethorphan) is okay for loosening congestion in your chest and throat, but it could prevent you from coughing the mucus up. You have to take it more often than other guaifenesin products.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
5.155573376102646Mucinex D
Reviews for Mucinex D (Guaifenesin / Pseudoephedrine)
76%
of people say Mucinex D (Guaifenesin / Pseudoephedrine) is worth it
41%
say it works well
7%
say it's a big hassle
Reviews for Robitussin Dm (Guaifenesin / Dextromethorphan)
75%
1% vs. Mucinex D (Guaifenesin / Pseudoephedrine)
37%
4% vs. Mucinex D (Guaifenesin / Pseudoephedrine)
7%
Same vs. Mucinex D (Guaifenesin / Pseudoephedrine)
Side effects
Mucinex DRobitussin DM

We haven’t found good data for Mucinex D side effects.

FDA side effect reports for Mucinex D »

We haven’t found good data for Robitussin DM side effects.

FDA side effect reports for Robitussin DM »
How it works
Mucinex DRobitussin DM
Mucinex D (Guaifenesin / Pseudoephedrine) is a combination medicine. Guaifenesin (an expectorant) breaks up and thins out mucus. Pseudoephedrine (a decongestant) clears your sinuses.Robitussin Dm (Guaifenesin / Dextromethorphan) is a combination medicine. Guaifenesin is an expectorant that breaks up and thins out mucus. Dextromethorphan is a cough suppressant.
Type of medication
Mucinex DRobitussin DM
ExpectorantDecongestantOver-the-counter
ExpectorantCough suppressantOver-the-counter
Available as
Mucinex DRobitussin DM
  • Extended release
  • Liquid
Used for (click to learn more)
Mucinex DRobitussin DM
Risk factors for serious side effects
Mucinex DRobitussin DM
  • History of high blood pressure
  • History of heart problems
  • Age 65 years or older
    Detailed Mucinex D (Guaifenesin / Pseudoephedrine) risks & warnings »
      • Using other medications that affect serotonin
        Detailed Robitussin Dm (Guaifenesin / Dextromethorphan) risks & warnings »
        Pregnancy category
        Mucinex DRobitussin DM
        NFDA pregnancy category (Unknown)

        The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

        See the FDA package insert
        NFDA pregnancy category (Unknown)

        The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

        See the FDA package insert
        Alcohol
        No specific alcohol-related info.No specific alcohol-related info.
        Food
        No specific food-related info.No specific food-related info.
        Kidneys and liver
        No specific kidneys and liver-related info.No specific kidneys and liver-related info.
        Sex
        No specific sex-related info.No specific sex-related info.
        Sleep
        No specific sleep-related info.No specific sleep-related info.
        Weight
        No specific weight-related info.No specific weight-related info.
        Upsides and benefits
        Mucinex DRobitussin DM
        • Mucinex D (Guaifenesin / Pseudoephedrine) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have sinus and chest congestion.
        • Helps loosen the mucus in your airways so that you can cough it up more easily.
        • Works well to clear nasal congestion and help you breathe better.
        • Robitussin Dm (Guaifenesin / Dextromethorphan) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have chest congestion and a cough.
        • Helps loosen the mucus and phlegm that builds up and causes productive, wet coughs.
        Downsides and risks
        Mucinex DRobitussin DM
        • Pseudoephedrine, the decongestant in Mucinex D (Guaifenesin / Pseudoephedrine), can make your heart race or make you feel anxious and restless.
        • Doesn't work as well if you use it for more than 4 days at a time.
        • Although you don't need a prescription to get Mucinex D (Guaifenesin / Pseudoephedrine), you need to show a photo ID to buy it in the drugstore.
        • Mucinex D (Guaifenesin / Pseudoephedrine) isn’t useful if you have a dry cough.
        • Robitussin Dm (Guaifenesin / Dextromethorphan) isn’t useful if you have a dry cough without mucus or phlegm.
        • The two medications in this product could potentially work against each other. Guaifenesin makes mucus easier to cough up, while dextromethorphan (the "DM" in Robitussin Dm (Guaifenesin / Dextromethorphan)) stops you from coughing.
        • Needs to be taken more often during the day than other products with guaifenesin, like Mucinex.
        • Can cause sleepiness, dizziness, and an upset stomach.
        Tips from our pharmacists for people taking the medication
        Mucinex DRobitussin DM
        • Drink plenty of fluids while taking Mucinex D (Guaifenesin / Pseudoephedrine) because liquid helps break down mucus.
        • You need to show an ID to buy Mucinex D (Guaifenesin / Pseudoephedrine) in the drugstore because it contains pseudoephedrine.
        • Don't take Mucinex D (Guaifenesin / Pseudoephedrine) too close to bedtime since it can keep you awake.
        • Can cause an irregular or fast heartbeat, and can raise your blood pressure.
        • Follow age-specific dosing instructions on how much to take. Don't take more than the recommended dose.
        • Drink plenty of fluids while taking Robitussin Dm (Guaifenesin / Dextromethorphan) because liquid helps break down mucus.
        • Cough suppressant starts working in 15 to 30 minutes.
        • If your cough lasts more than 7 days, call your doctor.
        • Follow age-specific dosing instructions on how much to take. Don't take more than the recommended dose.
        Learn more
        More about Mucinex DSide effectsReviews & ratingsAlternativesFDA package insert
        More about Robitussin DMSide effectsReviews & ratingsAlternativesFDA package insert