Compare Mucinex DM vs. Delsym

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Breaks up mucus and relieves cough.

Mucinex Dm (Dextromethorphan / Guaifenesin) is okay for loosening congestion in your chest and throat, but it could prevent you from coughing the mucus up. It comes as an extended-release tablet and a short-acting liquid.

3.9/ 5 average rating with 15 reviewsforMucinex DM
Relieves coughing.

Delsym (Dextromethorphan) is a good option for treating dry cough. It's not safe to take with MAO inhibitors though.

3.3/ 5 average rating with 127 reviewsforDelsym
Upsides
  • Mucinex Dm (Dextromethorphan / Guaifenesin) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have chest congestion and a cough.
  • Helps loosen the mucus and phlegm that builds up in productive and wet coughs.
  • The extended release version of Mucinex DM lasts up to 12 hours.
  • Good for treating dry cough.
  • Available in drugstores either by itself or in combination with other medications to treat cold and allergy symptoms.
  • Available as a liquid and a tablet.
  • Some products relieve cough for up to 12 hours.
Downsides
  • Mucinex Dm (Dextromethorphan / Guaifenesin) isn’t useful if you have a dry cough without mucus or phlegm.
  • The two medications in this product could potentially work against each other. Guaifenesin makes mucus easier to cough up, while dextromethorphan (the "DM" in Mucinex Dm (Dextromethorphan / Guaifenesin)) stops you from coughing.
  • Can cause sleepiness, dizziness, and an upset stomach.
  • Can't take dextromethorphan if you're taking MAO inhibitors (drugs used to treat Parkinson's disease, depression, and other emotional conditions). If taken together, they will cause dangerously high blood pressure levels.
  • If you're taking this in combination with other cold and allergy medications, you should read labels closely to make sure you're not accidentally taking too much of a single ingredient.
Used for
Dosage forms
  • Pill
  • Extended release
  • Liquid
  • Pill
  • Liquid extended release
No pricing information available
No pricing information available
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Reviews
15 reviews so far
73%
saidit'sworth it
73%
saiditworked well
13%
saidit'sa big hassle

Have you used Mucinex Dm (Dextromethorphan / Guaifenesin)?

Leave a review
127 reviews so far
63%
saidit'sworth it
32%
saiditworked well
12%
saidit'sa big hassle

Have you used Delsym (Dextromethorphan)?

Leave a review
Side effects
The Mucinex Dm (Dextromethorphan / Guaifenesin) FDA package insert doesn’t have numbers about how common side effects are.
The Delsym (Dextromethorphan) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Nausea and vomiting
  • Serotonin syndrome
    • Using other medications that affect serotonin
  • Cough warning
See more detailed risks and warnings
  • Serotonin syndrome
    • Using other medications that affect serotonin
See more detailed risks and warnings