Compare Mucinex DM vs. Mucinex D

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Mucinex Dm (Dextromethorphan / Guaifenesin)

Over-the-counter
Breaks up mucus and relieves cough.

Mucinex Dm (Dextromethorphan / Guaifenesin) is okay for loosening congestion in your chest and throat, but it could prevent you from coughing the mucus up. It comes as an extended-release tablet and a short-acting liquid.

5.4/ 7 average rating with 15 reviewsforMucinex DM
Breaks up mucus and relieves congestion.

Mucinex D (Guaifenesin / Pseudoephedrine) is good if you have a stuffy nose and a cough with mucus, but it could keep you up at night.

5.2/ 7 average rating with 1249 reviewsforMucinex D
Upsides
  • Mucinex Dm (Dextromethorphan / Guaifenesin) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have chest congestion and a cough.
  • Helps loosen the mucus and phlegm that builds up in productive and wet coughs.
  • The extended release version of Mucinex DM lasts up to 12 hours.
  • Mucinex D (Guaifenesin / Pseudoephedrine) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have sinus and chest congestion.
  • Helps loosen the mucus in your airways so that you can cough it up more easily.
  • Works well to clear nasal congestion and help you breathe better.
Downsides
  • Mucinex Dm (Dextromethorphan / Guaifenesin) isn’t useful if you have a dry cough without mucus or phlegm.
  • The two medications in this product could potentially work against each other. Guaifenesin makes mucus easier to cough up, while dextromethorphan (the "DM" in Mucinex Dm (Dextromethorphan / Guaifenesin)) stops you from coughing.
  • Can cause sleepiness, dizziness, and an upset stomach.
  • Pseudoephedrine, the decongestant in Mucinex D (Guaifenesin / Pseudoephedrine), can make your heart race or make you feel anxious and restless.
  • Doesn't work as well if you use it for more than 4 days at a time.
  • Although you don't need a prescription to get Mucinex D (Guaifenesin / Pseudoephedrine), you need to show a photo ID to buy it in the drugstore.
  • Mucinex D (Guaifenesin / Pseudoephedrine) isn’t useful if you have a dry cough.
Used for
Dosage forms
  • Pill
  • Extended release
  • Liquid
  • Extended release
No pricing information available
No pricing information available
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Reviews
15 
73%
think this treatment is worth it
73%
think this treatment works well
13%
think this treatment is a hassle

Have you used Mucinex Dm (Dextromethorphan / Guaifenesin)?

Leave a review
1249 
76%
think this treatment is worth it
41%
think this treatment works well
7%
think this treatment is a hassle

Have you used Mucinex D (Guaifenesin / Pseudoephedrine)?

Leave a review
Side effects
The Mucinex Dm (Dextromethorphan / Guaifenesin) FDA package insert doesn’t have numbers about how common side effects are.
The Mucinex D (Guaifenesin / Pseudoephedrine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Serotonin syndrome

    Using other medications that affect serotonin

See more detailed risks and warnings
  • High blood pressure

    History of high blood pressure

  • Heart problems

    History of heart problems

    ...and 1 more risk factors

See more detailed risks and warnings