Compare Mucinex DM vs. Robitussin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Mucinex Dm (Dextromethorphan / Guaifenesin)

Over-the-counter

Robitussin (Guaifenesin)

Over-the-counter
Breaks up mucus and relieves cough.

Mucinex Dm (Dextromethorphan / Guaifenesin) is okay for loosening congestion in your chest and throat, but it could prevent you from coughing the mucus up. It comes as an extended-release tablet and a short-acting liquid.

5.4/ 7 average rating with 15 reviewsforMucinex DM
Breaks up mucus that causes cough.

Robitussin (Guaifenesin) is a useful medicine for loosening congestion in your chest and throat, but it doesn't last as long as other guaifenesin products.

Upsides
  • Mucinex Dm (Dextromethorphan / Guaifenesin) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have chest congestion and a cough.
  • Helps loosen the mucus and phlegm that builds up in productive and wet coughs.
  • The extended release version of Mucinex DM lasts up to 12 hours.
  • Robitussin (Guaifenesin) reduces the thickness and amount of mucus in your throat and chest.
  • It’s available at the drugstore either by itself or in combination with other medications to treat cold and flu symptoms.
  • Available in multiple forms.
  • Can be used in children 12 years and older.
Downsides
  • Mucinex Dm (Dextromethorphan / Guaifenesin) isn’t useful if you have a dry cough without mucus or phlegm.
  • The two medications in this product could potentially work against each other. Guaifenesin makes mucus easier to cough up, while dextromethorphan (the "DM" in Mucinex Dm (Dextromethorphan / Guaifenesin)) stops you from coughing.
  • Can cause sleepiness, dizziness, and an upset stomach.
  • Robitussin (Guaifenesin) doesn't last as long as other products that contain guaifenesin. Mucinex's extended release form lasts 12 hours and Robitussin (Guaifenesin)'s lasts 8 hours.
  • You need to drink a lot of fluids while taking this medication or it won't work as well.
  • Robitussin (Guaifenesin) isn’t useful if you have a dry cough.
  • Can cause nausea, headache, and an upset stomach.
Used for
Dosage forms
  • Pill
  • Extended release
  • Liquid
  • Liquid
No pricing information available
No pricing information available
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Reviews
15 
73%
think this treatment is worth it
73%
think this treatment works well
13%
think this treatment is a hassle

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Side effects
The Mucinex Dm (Dextromethorphan / Guaifenesin) FDA package insert doesn’t have numbers about how common side effects are.
The Robitussin (Guaifenesin) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Serotonin syndrome

    Using other medications that affect serotonin

See more detailed risks and warnings