Compare Mucinex vs. Mucinex DM

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Mucinex
(Guaifenesin)

Mucinex Dm
(Dextromethorphan / Guaifenesin)

Breaks up mucus that causes cough. Mucinex (Guaifenesin) is a useful medicine for loosening congestion in your chest and throat, and it lasts longer than other guaifenesin products.Breaks up mucus and relieves cough. Mucinex Dm (Dextromethorphan / Guaifenesin) is okay for loosening congestion in your chest and throat, but it could prevent you from coughing the mucus up. It comes as an extended-release tablet and a short-acting liquid.
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Reviews & ratings
Button Group. All currently active
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5.226057906458798Mucinex
Reviews for Mucinex (Guaifenesin)
78%
of people say Mucinex (Guaifenesin) is worth it
47%
say it works well
7%
say it's a big hassle

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Side effects
MucinexMucinex DM

We haven’t found good data for Mucinex side effects.

FDA side effect reports for Mucinex »

We haven’t found good data for Mucinex DM side effects.

FDA side effect reports for Mucinex DM »
How it works
MucinexMucinex DM
Mucinex (Guaifenesin) is an expectorant. It contains guaifenesin, which thins and loosens mucus, making it easier to cough out.Mucinex Dm (Dextromethorphan / Guaifenesin) is a combination medicine. Guaifenesin is an expectorant that breaks up and thins out mucus. Dextromethorphan is a cough suppressant.
Type of medication
MucinexMucinex DM
ExpectorantOver-the-counter
Cough suppressantExpectorantOver-the-counter
Available as
MucinexMucinex DM
  • Extended release
  • Liquid
  • Pill
  • Extended release
  • Liquid
Used for (click to learn more)
MucinexMucinex DM
Risk factors for serious side effects
MucinexMucinex DM
    Detailed Mucinex (Guaifenesin) risks & warnings »
      • Using other medications that affect serotonin
        Detailed Mucinex Dm (Dextromethorphan / Guaifenesin) risks & warnings »
        Pregnancy category
        MucinexMucinex DM
        NFDA pregnancy category (Unknown)

        The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

        See the FDA package insert
        NFDA pregnancy category (Unknown)

        The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

        See the FDA package insert
        Alcohol
        • Mucinex (Guaifenesin) is alcohol- and sugar-free.
        No specific alcohol-related info.
        Food
        No specific food-related info.No specific food-related info.
        Kidneys and liver
        No specific kidneys and liver-related info.No specific kidneys and liver-related info.
        Sex
        No specific sex-related info.No specific sex-related info.
        Sleep
        No specific sleep-related info.No specific sleep-related info.
        Weight
        No specific weight-related info.No specific weight-related info.
        Upsides and benefits
        MucinexMucinex DM
        • Mucinex (Guaifenesin) reduces the thickness and amount of mucus in your throat and chest.
        • Lasts longer than some other products that contain guaifenesin, such as Robitussin, because it's an extended-release form.
        • It’s available at the drugstore either by itself or in combination with other medications to treat cold and flu symptoms.
        • Available in liquid and tablet forms.
        • Mucinex (Guaifenesin) is alcohol- and sugar-free.
        • Mucinex Dm (Dextromethorphan / Guaifenesin) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have chest congestion and a cough.
        • Helps loosen the mucus and phlegm that builds up in productive and wet coughs.
        • The extended release version of Mucinex DM lasts up to 12 hours.
        Downsides and risks
        MucinexMucinex DM
        • Mucinex (Guaifenesin) is more expensive than other medications that treat congestion.
        • You need to drink a lot of fluids while taking this medication or it won't work as well.
        • Mucinex (Guaifenesin) isn’t useful if you have a dry cough.
        • Can cause nausea, headache, and an upset stomach.
        • Mucinex Dm (Dextromethorphan / Guaifenesin) isn’t useful if you have a dry cough without mucus or phlegm.
        • The two medications in this product could potentially work against each other. Guaifenesin makes mucus easier to cough up, while dextromethorphan (the "DM" in Mucinex Dm (Dextromethorphan / Guaifenesin)) stops you from coughing.
        • Can cause sleepiness, dizziness, and an upset stomach.
        Tips from our pharmacists for people taking the medication
        MucinexMucinex DM
        • Drink plenty of fluids while taking Mucinex (Guaifenesin) because liquid helps break down mucus.
        • Steam from a humidifier, cool mist vaporizer, or hot shower can also help add moisture to your airways.
        • Follow age-specific dosing instructions on how much to take.
        • Mucinex (Guaifenesin) only works for coughs with mucus, so don't use it if you have a dry cough.
        • If your cough lasts more than 7 days, call your doctor.
        • Cough suppressant starts working in 15 to 30 minutes.
        • Follow age-specific dosing instructions on how much to take. Don't take more than the recommended dose.
        • Drink plenty of fluids while taking Mucinex Dm (Dextromethorphan / Guaifenesin) because liquid helps break down mucus.
        • If your cough lasts more than 7 days, call your doctor.
        Learn more
        More about MucinexSide effectsReviews & ratingsAlternativesFDA package insert
        More about Mucinex DMSide effectsReviews & ratingsAlternativesFDA package insert