Compare Mucinex vs. Robitussin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Mucinex (Guaifenesin)

Over-the-counter

Robitussin (Guaifenesin)

Over-the-counter
Breaks up mucus that causes cough.

Mucinex (Guaifenesin) is a useful medicine for loosening congestion in your chest and throat, and it lasts longer than other guaifenesin products.

3.8/ 5 average rating with 902 reviewsforMucinex
Breaks up mucus that causes cough.

Robitussin (Guaifenesin) is a useful medicine for loosening congestion in your chest and throat, but it doesn't last as long as other guaifenesin products.

Upsides
  • Mucinex (Guaifenesin) reduces the thickness and amount of mucus in your throat and chest.
  • Lasts longer than some other products that contain guaifenesin, such as Robitussin, because it's an extended-release form.
  • It’s available at the drugstore either by itself or in combination with other medications to treat cold and flu symptoms.
  • Available in liquid and tablet forms.
  • Mucinex (Guaifenesin) is alcohol- and sugar-free.
  • Robitussin (Guaifenesin) reduces the thickness and amount of mucus in your throat and chest.
  • It’s available at the drugstore either by itself or in combination with other medications to treat cold and flu symptoms.
  • Available in multiple forms.
  • Can be used in children 12 years and older.
Downsides
  • Mucinex (Guaifenesin) is more expensive than other medications that treat congestion.
  • You need to drink a lot of fluids while taking this medication or it won't work as well.
  • Mucinex (Guaifenesin) isn’t useful if you have a dry cough.
  • Can cause nausea, headache, and an upset stomach.
  • Robitussin (Guaifenesin) doesn't last as long as other products that contain guaifenesin. Mucinex's extended release form lasts 12 hours and Robitussin (Guaifenesin)'s lasts 8 hours.
  • You need to drink a lot of fluids while taking this medication or it won't work as well.
  • Robitussin (Guaifenesin) isn’t useful if you have a dry cough.
  • Can cause nausea, headache, and an upset stomach.
Used for
Dosage forms
  • Extended release
  • Liquid
  • Liquid
No pricing information available
No pricing information available
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Reviews
902 reviews so far
78%
saidit'sworth it
47%
saiditworked well
7%
saidit'sa big hassle

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Side effects
The Mucinex (Guaifenesin) FDA package insert doesn’t have numbers about how common side effects are.
The Robitussin (Guaifenesin) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors