Compare Mucinex vs. Robitussin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Mucinex
(Guaifenesin)

Robitussin
(Guaifenesin)

Breaks up mucus that causes cough. Mucinex (Guaifenesin) is a useful medicine for loosening congestion in your chest and throat, and it lasts longer than other guaifenesin products.Breaks up mucus that causes cough. Robitussin (Guaifenesin) is a useful medicine for loosening congestion in your chest and throat, but it doesn't last as long as other guaifenesin products.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.22Mucinex
Reviews for Mucinex (Guaifenesin)
78%
of people (All ages) say Mucinex (Guaifenesin) is worth it
47%
say it works well
7%
say it's a big hassle
902 reviews
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Have you used Robitussin (Guaifenesin)?
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Side effects
MucinexRobitussin

We haven’t found good data for Mucinex side effects.

FDA side effect reports for Mucinex »

We haven’t found good data for Robitussin side effects.

FDA side effect reports for Robitussin »
How it works
MucinexRobitussin
Mucinex (Guaifenesin) is an expectorant. It contains guaifenesin, which thins and loosens mucus, making it easier to cough out.Robitussin (Guaifenesin) is an expectorant. It contains guaifenesin, which thins and loosens mucus, making it easier to cough out.
Type of medication
MucinexRobitussin
ExpectorantOver-the-counter
ExpectorantOver-the-counter
Available as
MucinexRobitussin
  • Extended release
  • Liquid
  • Liquid
Used for (click to learn more)
MucinexRobitussin
Risk factors for serious side effects
MucinexRobitussin
    Detailed risks & warnings »
      Detailed risks & warnings »
      Pregnancy

      The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

      The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

      Alcohol
      MucinexRobitussin
      • Mucinex (Guaifenesin) is alcohol- and sugar-free.
      No alcohol related info.
      Upsides and benefits
      MucinexRobitussin
      • Mucinex (Guaifenesin) reduces the thickness and amount of mucus in your throat and chest.
      • Lasts longer than some other products that contain guaifenesin, such as Robitussin, because it's an extended-release form.
      • Available in liquid and tablet forms.
      • Mucinex (Guaifenesin) is alcohol- and sugar-free.
      • It’s available at the drugstore either by itself or in combination with other medications to treat cold and flu symptoms.
      • Robitussin (Guaifenesin) reduces the thickness and amount of mucus in your throat and chest.
      • Available in multiple forms.
      • Can be used in children 12 years and older.
      • It’s available at the drugstore either by itself or in combination with other medications to treat cold and flu symptoms.
      Downsides and risks
      MucinexRobitussin
      • Mucinex (Guaifenesin) is more expensive than other medications that treat congestion.
      • Mucinex (Guaifenesin) isn’t useful if you have a dry cough.
      • You need to drink a lot of fluids while taking this medication or it won't work as well.
      • Can cause nausea, headache, and an upset stomach.
      • Robitussin (Guaifenesin) doesn't last as long as other products that contain guaifenesin. Mucinex's extended release form lasts 12 hours and Robitussin (Guaifenesin)'s lasts 8 hours.
      • Robitussin (Guaifenesin) isn’t useful if you have a dry cough.
      • You need to drink a lot of fluids while taking this medication or it won't work as well.
      • Can cause nausea, headache, and an upset stomach.
      Tips from our pharmacists for people taking the medication
      MucinexRobitussin
      • Drink plenty of fluids while taking Mucinex (Guaifenesin) because liquid helps break down mucus.
      • Mucinex (Guaifenesin) only works for coughs with mucus, so don't use it if you have a dry cough.
      • Steam from a humidifier, cool mist vaporizer, or hot shower can also help add moisture to your airways.
      • Follow age-specific dosing instructions on how much to take.
      • If your cough lasts more than 7 days, call your doctor.
      • Drink plenty of fluids while taking Robitussin (Guaifenesin) because liquid helps break down mucus.
      • Robitussin (Guaifenesin) only works for coughs with mucus, so don't use it if you have a dry cough.
      • Steam from a humidifier, cool mist vaporizer, or hot shower can also help add moisture to your airways.
      • Follow age-specific dosing instructions on how much to take.
      • If your cough lasts more than 7 days, call your doctor.
      Learn more
      More about MucinexSide effectsReviews & ratingsAlternativesFDA package insert
      Have you used Mucinex (Guaifenesin)?
      Worth itNot sureNot worth it
      More about RobitussinSide effectsReviews & ratingsAlternativesFDA package insert
      Have you used Robitussin (Guaifenesin)?
      Worth itNot sureNot worth it