Compare Mucinex vs. Robitussin DM

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Mucinex (Guaifenesin)

Over-the-counter
Breaks up mucus that causes cough.

Mucinex (Guaifenesin) is a useful medicine for loosening congestion in your chest and throat, and it lasts longer than other guaifenesin products.

5.2/ 7 average rating with 902 reviewsforMucinex
Breaks up mucus and relieves cough.

Robitussin Dm (Guaifenesin / Dextromethorphan) is okay for loosening congestion in your chest and throat, but it could prevent you from coughing the mucus up. You have to take it more often than other guaifenesin products.

5.0/ 7 average rating with 724 reviewsforRobitussin DM
Upsides
  • Mucinex (Guaifenesin) reduces the thickness and amount of mucus in your throat and chest.
  • Lasts longer than some other products that contain guaifenesin, such as Robitussin, because it's an extended-release form.
  • It’s available at the drugstore either by itself or in combination with other medications to treat cold and flu symptoms.
  • Available in liquid and tablet forms.
  • Mucinex (Guaifenesin) is alcohol- and sugar-free.
  • Robitussin Dm (Guaifenesin / Dextromethorphan) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have chest congestion and a cough.
  • Helps loosen the mucus and phlegm that builds up and causes productive, wet coughs.
Downsides
  • Mucinex (Guaifenesin) is more expensive than other medications that treat congestion.
  • You need to drink a lot of fluids while taking this medication or it won't work as well.
  • Mucinex (Guaifenesin) isn’t useful if you have a dry cough.
  • Can cause nausea, headache, and an upset stomach.
  • Robitussin Dm (Guaifenesin / Dextromethorphan) isn’t useful if you have a dry cough without mucus or phlegm.
  • The two medications in this product could potentially work against each other. Guaifenesin makes mucus easier to cough up, while dextromethorphan (the "DM" in Robitussin Dm (Guaifenesin / Dextromethorphan)) stops you from coughing.
  • Needs to be taken more often during the day than other products with guaifenesin, like Mucinex.
  • Can cause sleepiness, dizziness, and an upset stomach.
Used for
Dosage forms
  • Extended release
  • Liquid
  • Liquid
No pricing information available
No pricing information available
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Reviews
902 
78%
think this treatment is worth it
47%
think this treatment works well
7%
think this treatment is a hassle

Have you used Mucinex (Guaifenesin)?

Leave a review
724 
75%
think this treatment is worth it
37%
think this treatment works well
7%
think this treatment is a hassle

Have you used Robitussin Dm (Guaifenesin / Dextromethorphan)?

Leave a review
Side effects
The Mucinex (Guaifenesin) FDA package insert doesn’t have numbers about how common side effects are.
The Robitussin Dm (Guaifenesin / Dextromethorphan) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
See more detailed risks and warnings
  • Serotonin syndrome

    Using other medications that affect serotonin

See more detailed risks and warnings