Compare Naproxen vs. Meloxicam

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Aleve
(Naproxen)

Mobic
(Meloxicam)

Relieves pain, fever, and inflammation. Aleve (Naproxen) works well for mild to moderate pain and inflammation, and it lasts longer than other NSAIDs.Relieves pain and inflammation. Mobic (Meloxicam) works well for treating pain and causes less upset stomach than other NSAIDs.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.31Naproxen
Reviews for Aleve (Naproxen)
78%
of people (All ages) say Aleve (Naproxen) is worth it
48%
say it works well
5%
say it's a big hassle
978 reviews
Have you used Aleve (Naproxen)?
Worth itNot sureNot worth it
Reviews for Mobic (Meloxicam)
64%
14% vs. Aleve (Naproxen)
54%
+6% vs. Aleve (Naproxen)
13%
8% vs. Aleve (Naproxen)
141 reviews
Have you used Mobic (Meloxicam)?
Worth itNot sureNot worth it
Side effects
NaproxenMeloxicam

The Naproxen FDA package insert doesn’t have numbers about how common side effects are.

More about Naproxen side effects »
  • Gastrointestinal disorders 5%
  • Diarrhea 4%
  • Infection and infestations 3%
  • Accident household 3%
  • Swelling due to excess fluid 2%
  • Dyspeptic signs and symptoms 2%
  • Sore throat 2%
  • Dizziness 1%
  • Flu-like symptomsa-like symptoms 1%
More Meloxicam side effects »
How it works
NaproxenMeloxicam
Aleve (Naproxen) is a non-steroidal anti-inflammatory drug (NSAID). It blocks the inflammation process in your body, which relieves swelling and pain.Mobic (Meloxicam) is a non-steroidal anti-inflammatory drug (NSAID). It blocks the inflammation process in your body, which relieves swelling and pain.
Type of medication
NaproxenMeloxicam
Pain reliever
Nonsteroidal anti-inflammatory drug (NSAID)
Prescription or OTC
Pain reliever
Nonsteroidal anti-inflammatory drug (NSAID)
Prescription only
Available as
NaproxenMeloxicam
  • Pill
  • Delayed release tablet
  • Liquid
  • Pill
  • Liquid
Used for (click to learn more)
NaproxenMeloxicam
Risk factors for serious side effects
NaproxenMeloxicam
  • History of heart problems
  • High blood pressure
  • High cholesterol
  • Diabetes
  • Smoking
Detailed risks & warnings »
  • History of heart attack
  • History of heart surgery
  • High blood pressure
  • High Cholesterol
  • Diabetes
Detailed risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Food
NaproxenMeloxicam
  • It needs to be taken with food to avoid getting an upset stomach.
  • Take it with a meal or a snack to prevent an upset stomach.
  • Take Mobic (Meloxicam) only once a day. Take it with a meal or a snack to prevent an upset stomach.
Kidneys and liver
NaproxenMeloxicam
  • It can cause serious kidney and stomach problems (like ulcers and bleeding) the longer you take it.
  • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
  • Aleve (Naproxen) is an NSAID that can lower kidney function or cause damage. Taking the lowest dose for the shortest amount of time lowers your risk. Your doctor should check your kidney function if you take Aleve (Naproxen) for any amount of time.
  • Can also affect your kidneys or cause permanent kidney damage if taken for a long time.
  • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
  • Mobic (Meloxicam), and similar medications in the NSAID family, can lower kidney function or cause permanent kidney damage. Taking the lowest dose for the shortest amount of time necessary can lower your risk for kidney problems. It is important to get lab tests to check your kidney function periodically if you use Mobic (Meloxicam) for long periods of time.
Pain
NaproxenMeloxicam
  • Works well to relieve pain, swelling, and fevers.
  • Starts relieving pain in 30 to 60 minutes.
  • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
  • Works well to relieve pain and inflammation from osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
  • Good for muscle aches and pains.
  • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
Upsides and benefits
NaproxenMeloxicam
  • Works well to relieve pain, swelling, and fevers.
  • Good for menstrual cramps, toothaches, body aches, and mild arthritis pain.
  • Lasts longer than Ibuprofen, so you can take it less often.
  • Aleve (Naproxen) works as well as Aspirin and Indomethacin to treat arthritis pain, and causes fewer stomach problems.
  • Although not without side effects, it's been around for a long time and is generally safe for short-term use.
  • Works well to relieve pain and inflammation from osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
  • Good for muscle aches and pains.
  • It lasts longer than Ibuprofen, so you can take it less often.
  • Causes less upset stomach than other NSAIDs, like Ibuprofen.
  • Can also caus less bruising or bleeding than other NSAIDs when taken at lower doses (7.5 mg per day or less).
Downsides and risks
NaproxenMeloxicam
  • It needs to be taken with food to avoid getting an upset stomach.
  • Can't be taken by pregnant women.
  • It can cause serious kidney and stomach problems (like ulcers and bleeding) the longer you take it.
  • Like all NSAIDs, it can raise your risk of having blood clots, heart attack, or stroke.
  • The longer you take Mobic (Meloxicam), the more likely you are to have stomach problems, including inflammation, ulcers, and bleeding. This can also happen if you take Mobic (Meloxicam) on an empty stomach.
  • Like all NSAIDs, it can raise your risk of blood clots, heart attack, or a stroke.
  • Can also affect your kidneys or cause permanent kidney damage if taken for a long time.
Tips from our pharmacists for people taking the medication
NaproxenMeloxicam
  • Starts relieving pain in 30 to 60 minutes.
  • Take it with a meal or a snack to prevent an upset stomach.
  • Can make you bruise or bleed more easily and it can also cause stomach ulcers.
  • Don't take it with other blood thinners, like aspirin, unless your doctor tells you it's safe.
  • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
  • Take Mobic (Meloxicam) only once a day. Take it with a meal or a snack to prevent an upset stomach.
  • Can make you bruise or bleed more easily and it can also cause stomach ulcers.
  • Don't take it with other blood thinners, like aspirin, unless your doctor tells you it's safe.
  • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
Learn more
More about NaproxenSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Aleve (Naproxen)?
Worth itNot sureNot worth it
More about MeloxicamSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Mobic (Meloxicam)?
Worth itNot sureNot worth it