Compare naproxen vs. Morphine Sulfate

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Aleve (naproxen)

Prescription or OTC
Relieves pain, fever, and inflammation.

Aleve (naproxen) works well for treating mild to moderate pain or inflammation and lasts longer than other NSAIDs.

3.9/ 5 average rating with 978 reviewsfornaproxen
Treats severe pain.

Ms Contin (Morphine Sulfate) provides good long-term pain control without the need to take medicine frequently, but watch out for constipation.

3.5/ 5 average rating with 541 reviewsforMorphine Sulfate
Upsides
  • Aleve (naproxen) is effective for treating pain, inflammation, and fever.
  • Good for relieving pain from common conditions like menstrual cramps, toothaches, backache, and arthritis.
  • It lasts longer than other NSAIDS so you don't have to take it as often.
  • Aleve (naproxen) is generally safe to use, cheap, and available over-the-counter.
  • Aleve (naproxen) causes less stomach problems than its alternatives.
  • Provides longer relieve for moderate to severe pain to improve quality of life.
  • Good for chronic pain that requires around-the-clock relief.
  • Might have fewer side effects than other opioid pain relievers.
Downsides
  • Aleve (naproxen) needs to be taken with food or millk to lower the chances of getting an upset stomach.
  • Like all NSAIDs, Aleve (naproxen) is as not safe for pregnant women and people who are age 60 or older compared to some alternatives.
  • It can cause serious complications like stomach bleeding and kidney problems if taken for a long period of time.
  • Like all NSAIDs, Aleve (naproxen) can raise your risk of getting blood clots, a heart attack, or stroke.
  • Doesn't work for as-needed or quick pain relief.
  • Dizziness and drowsiness is common, but your body may adjust.
  • Everyone will get constipation - always stay hydrated and take stool softener or stimulant on days you're taking Ms Contin (Morphine Sulfate) if you need.
  • Long term use will likely cause physical dependence.
  • Must be weaned slowly off the medicine after use longer than 2 weeks.
Used for
Dosage forms
  • Pill
  • Delayed-release pill
  • Extended-release pill
  • Suspension
  • Pill
  • Extended release
  • Oral solution
  • Liquid
  • Suppository
Price
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Reviews
978 reviews so far
78%
saidit'sworth it
48%
saiditworked well
5%
saidit'sa big hassle

Have you used Aleve (naproxen)?

Leave a review
541 reviews so far
55%
saidit'sworth it
43%
saiditworked well
20%
saidit'sa big hassle

Have you used Ms Contin (Morphine Sulfate)?

Leave a review
Side effects
The Aleve (naproxen) FDA package insert doesn’t have numbers about how common side effects are.
The Ms Contin (Morphine Sulfate) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Heart attack and stroke
    • History of heart problems
    • Taking the medicine for a long period of time
  • Stomach bleeding
    • History of stomach bleeding or ulcer
    • Age 60 or older
    • Taking aspirin, other NSAIDs, or blood thinners
    • Drinking more than 3 alcoholic beverages a day
    • Smoking
    • Taking the medicine for a long period of time
  • Severe allergic reaction
    • Asthma
    • Nasal polyps
    • Aspirin allergy
    • NSAID allergy
  • Kidney damage
    • Kidney disease
    • Heart failure
    • Taking certain high blood pressure medications
    • Age 60 or older
    • Taking the medicine for a long period of time
  • Harm to fetus (unborn baby)
    • Women who want to or can become pregnant
    • Pregnant women
See more detailed risks and warnings
  • Death from lack of oxygen to the body (respiratory depression)
    • Current use of medicine that affects liver enzyme CYP 3A4
    • Age 65 or greater
    • Higher dose
    • People with not enough thyroid hormones
    • History of lung problems
  • Death from overdose
    • Children age 18 and younger
  • Death in newborn babies from opioid withdrawal (Neonatal opioid withdrawal syndrome)
    • Long-term use during pregnancy
  • Tolerance, dependence, and addiction
    • Taking more than the prescribed dose
    • Long-term use
    • History of drug abuse
  • Driving impairment
    • Taking with alcohol
    • Taking other medicines that make you less alert
    • Age 65 or greater
  • Low blood pressure
    • Age 65 years or older
See more detailed risks and warnings