Compare Nasonex vs. Advil Allergy and Congestion Relief

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Advil Allergy And Congestion Relief
(Chlorpheniramine / Ibuprofen / Phenylephrine)

Relieves allergy symptoms. Nasonex (Mometasone) is a good first-choice treatment for stuffy and runny noses caused by allergies.Relieves cold and allergy symptoms. Advil Allergy And Congestion Relief (Chlorpheniramine / Ibuprofen / Phenylephrine) is an okay combination medicine to relieve pain and congestion. The antihistamine can make you sleepy and the decongestant can keep you awake, so it could affect you either way.
How it works
Nasonex (Mometasone) is a topical steroid. It works directly where it's applied to help reduce swelling and inflammation in your nose.Advil Allergy And Congestion Relief (Chlorpheniramine / Ibuprofen / Phenylephrine) is a combination medicine that treats cold and allergy symptoms. Ibuprofen is an NSAID that relieves swelling, pain, and fever. Chlorpheniramine is an antihistamine that treats runny nose and watery eyes. Phenylephrine is a decongestant that clears your sinuses.
Type of medication
Prescription only
1st generation
Pain reliever
Available as
  • Nasal spray
  • Pill
Used for (click to learn more)
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
Reviews for Nasonex (Mometasone)
of people say Nasonex (Mometasone) is worth it
say it works well
say it's a big hassle
Reviews for Advil Allergy And Congestion Relief (Chlorpheniramine / Ibuprofen / Phenylephrine)
+5% vs. Nasonex (Mometasone)
8% vs. Nasonex (Mometasone)
+2% vs. Nasonex (Mometasone)
Side effects
  • Nosebleed 8%
  • Headache 4%
  • Viral infection 3%
  • Menstrual cramps 2%
  • Sinus inflammation 2%
  • Musculoskeletal pain 2%
  • Sore throat 2%
  • Coughing 1%
  • Vomiting 1%
More Nasonex side effects »

We haven’t found good data for Advil Allergy and Congestion Relief side effects.

FDA side effect reports for Advil Allergy and Congestion Relief »
Risk factors for serious side effects
  • Long-term use
  • Long-term use
  • Surgery or trauma to the nose or sinuses
  • Long-term use
  • Exposure to immunizable diseases (chickenpox and measles)
  • Exposure to tuberculosis
  • Long-term use
  • Taking more than recommended dose
Detailed Nasonex (Mometasone) risks & warnings »
  • History of stomach bleeding or ulcers
  • Age 60 years or older
  • Taking aspirin, NSAIDs, or blood thinners
  • Drinking more than 3 alcoholic beverages a day
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • Women of childbearing age
  • Kidney disease
  • Heart failure
  • Liver disease
  • Taking high blood pressure medications
  • Age 65 years or older
  • History of high blood pressure
  • History of heart problems
  • Age 65 years or older
  • Taking with aspirin
Detailed Advil Allergy And Congestion Relief (Chlorpheniramine / Ibuprofen / Phenylephrine) risks & warnings »
Pregnancy category
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
NFDA pregnancy category (Unknown)

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

See the FDA package insert
No specific alcohol-related info.
  • While taking this, avoid alcohol and other drugs that make you drowsy.
No specific food-related info.No specific food-related info.
Kidneys and liver
No specific kidneys and liver-related info.
  • Advil Allergy And Congestion Relief (Chlorpheniramine / Ibuprofen / Phenylephrine) contains ibuprofen, an NSAID that can lower kidney function or cause damage. Taking the lowest dose for the shortest amount of time lowers your risk. Your doctor should check your kidney function if you take Advil Allergy And Congestion Relief (Chlorpheniramine / Ibuprofen / Phenylephrine) for any amount of time.
No specific sex-related info.No specific sex-related info.
No specific sleep-related info.No specific sleep-related info.
No specific weight-related info.No specific weight-related info.
Upsides and benefits
  • First-choice medication for treating runny and stuffy noses caused by allergies. It works by reducing inflammation in the nose.
  • Because it's used directly where the inflammation is happening, it has fewer side effects than oral steroids do and has a lower chance of causing withdrawal symptoms once the medication is stopped.
  • Can be used as needed to help control symptoms in people age 13 years or older.
  • Available as a generic, which is cheaper.
  • Advil Allergy And Congestion Relief (Chlorpheniramine / Ibuprofen / Phenylephrine) is a combination medicine that relieves multiple cold and allergy symptoms. It's good to use if you have a stuffy nose, sinus pressure, and pain.
  • The decongestant (phenylephrine) has fewer side effects than other decongestants like pseudoephedrine. It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
Downsides and risks
  • Needs to be primed 10 times before it can be used, or re-primed if not used for more than 2 weeks.
  • Doesn't have a counter on it, so it can be hard to remember how many sprays are left (each bottle has 120 sprays).
  • Since the medicine in Nasonex (Mometasone) is a steroid, it can slow down your healing process if you've hurt your nose or had nose surgery.
  • If you don't really need all of the medications in this combination, you're taking extra medicine and might have extra side effects for no reason.
  • Phenylephrine doesn't last as long as other decongestants like pseudoephedrine.
  • You shouldn't use it if you have high blood pressure.
  • The pain reliever (ibuprofen) can interact with other medications and make health problems like stomach bleeding and ulcers worse.
  • It's not safe to take ibuprofen if you're pregnant since it increases the risk of heart defects in babies.
Tips from our pharmacists for people taking the medication
  • Use Nasonex (Mometasone) once a day, following age-specific recommendations on how many sprays to use. Don't take more than prescribed.
  • Blow your nose before using.
  • Can cause thrush (a fungal infection) inside your nose and throat. Can also cause nosebleeds, a sore throat, and headaches.
  • Needs to be used regularly during allergy season for it to work. It can take 1 to 2 weeks for the medicine to start working fully.
  • Check with your doctor or pharmacist on how to use the nasal spray the right way.
  • Shake well before using it. Before the first use, prime the bottle by spraying it until you see a fine mist.
  • Don't take it if you have an allergy to aspirin since ibuprofen can cause a similar reaction.
  • Chlorpheniramine (the antihistamine ingredient in Advil Allergy And Congestion Relief (Chlorpheniramine / Ibuprofen / Phenylephrine)) can make you sleepy, so avoid activities that require you to be fully alert until you know how it affects you.
  • While taking this, avoid alcohol and other drugs that make you drowsy.
  • Phenylephrine (the decongestant ingredient) can make you restless, so don't take it too close to bedtime.
  • Let your doctor know if your symptoms don't improve in a few days.
  • Don't use in kids age 12 years or younger.
Learn more
More about NasonexSide effectsReviews & ratingsAlternativesFDA package insert
More about Advil Allergy and Congestion ReliefSide effectsReviews & ratingsAlternativesFDA package insert