Compare Nasonex vs. Nyquil Cold And Flu

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Nasonex (Mometasone)

Prescription only
Relieves allergy symptoms.

Nasonex (Mometasone) is a good first-choice treatment for stuffy and runny noses caused by allergies.

5.0/ 7 average rating with 675 reviewsforNasonex
Relieves cold and flu symptoms, and helps you sleep.

Nyquil Cold And Flu (Acetaminophen / Dextromethorphan / Doxylamine) is a useful combination medicine that relieves cold and flu symptoms and will help you sleep. Make sure you really need all of its ingredients.

5.3/ 7 average rating with 1188 reviewsforNyquil Cold And Flu
Upsides
  • First-choice medication for treating runny and stuffy noses caused by allergies. It works by reducing inflammation in the nose.
  • Because it's used directly where the inflammation is happening, it has fewer side effects than oral steroids do and has a lower chance of causing withdrawal symptoms once the medication is stopped.
  • Can be used as needed to help control symptoms in people age 13 years or older.
  • Available as a generic, which is cheaper.
  • Nyquil Cold And Flu (Acetaminophen / Dextromethorphan / Doxylamine) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have watery eyes, a cough, fever, and pain.
  • The cough medicine (dextromethorphan) works well and has very few side effects.
  • The pain reliever (acetaminophen) is easier on your stomach and has fewer drug interactions than other pain medications like aspirin or ibuprofen.
  • The antihistamine (doxylamine) will help you sleep.
Downsides
  • Needs to be primed 10 times before it can be used, or re-primed if not used for more than 2 weeks.
  • Doesn't have a counter on it, so it can be hard to remember how many sprays are left (each bottle has 120 sprays).
  • Since the medicine in Nasonex (Mometasone) is a steroid, it can slow down your healing process if you've hurt your nose or had nose surgery.
  • If you don't really need all of the medications in this combination, you're taking extra medicine and might have extra side effects for no reason.
  • You shouldn't use it if you have high blood pressure.
  • To avoid hurting your liver, you have to keep track of the total amount of acetaminophen (APAP) you're taking since it's a very common ingredient in pain and cold/flu combination medicines.
Used for
Dosage forms
  • Nasal spray
  • Pill
  • Liquid
Price
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$7.32
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Reviews
675 
68%
think this treatment is worth it
39%
think this treatment works well
8%
think this treatment is a hassle

Have you used Nasonex (Mometasone)?

Leave a review
1188 
83%
think this treatment is worth it
42%
think this treatment works well
7%
think this treatment is a hassle

Have you used Nyquil Cold And Flu (Acetaminophen / Dextromethorphan / Doxylamine)?

Leave a review
Side effects
The Nasonex (Mometasone) FDA package insert doesn’t have numbers about how common side effects are.
The Nyquil Cold And Flu (Acetaminophen / Dextromethorphan / Doxylamine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Thrush in the nose and throat

    Long-term use

  • Changes in the nasal septum

    Long-term use

  • Decreased wound healing

    Surgery or trauma to the nose or sinuses

  • Glaucoma and cataracts

    Long-term use

  • Reduced immune system

    Exposure to immunizable diseases (chickenpox and measles)

    ...and 1 more risk factors

  • Decrease in growth in children and teenagers

    Long-term use

    ...and 1 more risk factors

See more detailed risks and warnings
  • Liver damage

    Drinking more than 2 alcoholic beverages a day

    ...and 2 more risk factors

  • Serotonin syndrome

    Using other medications that affect serotonin

  • Driving impairment

    Taking with alcohol

    ...and 1 more risk factors

  • Antihistamine side effects

    Age 65 years or older

    ...and 2 more risk factors

See more detailed risks and warnings