Compare Nasonex vs. Sudafed

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Nasonex (Mometasone)

Prescription only

Sudafed (Pseudoephedrine)

Prescription or OTC
Relieves allergy symptoms.

Nasonex (Mometasone) is a good first-choice treatment for stuffy and runny noses caused by allergies.

5.0/ 7 average rating with 675 reviewsforNasonex
Clears your sinuses.

Sudafed (Pseudoephedrine) relieves stuffy nose, but it could keep you up at night. Don't forget your photo ID or you won't be able to buy it in the drugstore.

5.3/ 7 average rating with 1740 reviewsforSudafed
Upsides
  • First-choice medication for treating runny and stuffy noses caused by allergies. It works by reducing inflammation in the nose.
  • Because it's used directly where the inflammation is happening, it has fewer side effects than oral steroids do and has a lower chance of causing withdrawal symptoms once the medication is stopped.
  • Can be used as needed to help control symptoms in people age 13 years or older.
  • Available as a generic, which is cheaper.
  • One of the best over-the-counter options to clear stuffy nose and help you breathe better.
  • Clears nasal congestion better than other decongestants like phenylephrine.
  • Can be helpful in relieving congestion-related headaches and pressure in your ears.
  • Available in regular and extended release forms.
Downsides
  • Needs to be primed 10 times before it can be used, or re-primed if not used for more than 2 weeks.
  • Doesn't have a counter on it, so it can be hard to remember how many sprays are left (each bottle has 120 sprays).
  • Since the medicine in Nasonex (Mometasone) is a steroid, it can slow down your healing process if you've hurt your nose or had nose surgery.
  • Pseudoephedrine (a decongestant) can make your heart race or make you feel anxious and restless.
  • It can affect the quality of your sleep, so you can't take it too close to going to bed.
  • Can raise blood pressure so check with your doctor before using it if you have high blood pressure or other heart conditions.
  • Sudafed (Pseudoephedrine) isn't as effective after using it for more than 4 days straight.
  • Need to show a photo ID to buy it in the drugstore and there is a limit on how much you can buy each visit.
Used for
Dosage forms
  • Nasal spray
  • Pill
  • Extended release
  • Liquid
Price
Lowest price near you
$7.32
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Reviews
675 
68%
think this treatment is worth it
39%
think this treatment works well
8%
think this treatment is a hassle

Have you used Nasonex (Mometasone)?

Leave a review
1740 
82%
think this treatment is worth it
45%
think this treatment works well
6%
think this treatment is a hassle

Have you used Sudafed (Pseudoephedrine)?

Leave a review
Side effects
The Nasonex (Mometasone) FDA package insert doesn’t have numbers about how common side effects are.
The Sudafed (Pseudoephedrine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Thrush in the nose and throat

    Long-term use

  • Changes in the nasal septum

    Long-term use

  • Decreased wound healing

    Surgery or trauma to the nose or sinuses

  • Glaucoma and cataracts

    Long-term use

  • Reduced immune system

    Exposure to immunizable diseases (chickenpox and measles)

    ...and 1 more risk factors

  • Decrease in growth in children and teenagers

    Long-term use

    ...and 1 more risk factors

See more detailed risks and warnings
  • High blood pressure

    History of high blood pressure

  • Heart problems

    History of heart problems

    ...and 1 more risk factors

  • Seizures

    History of seizures

  • Harm to fetus

    Women of childbearing age

See more detailed risks and warnings