Compare Nesina vs. Glucotrol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Nesina
(Alogliptin)

Glucotrol
(Glipizide)

Lowers your blood sugar. alogliptin is a good add-on treatment if your blood sugar is still too high, but you don't want to use an injectable medicine.Lowers blood sugar. Glucotrol (Glipizide) is a very effective oral blood sugar-lowering medicine. It can cause low blood sugar, so make sure you know what the symptoms are and always have a source of sugar nearby.
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Reviews & ratings
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Reviews for Glucotrol (Glipizide)
50%
50% vs. Nesina (Alogliptin)
32%
68% vs. Nesina (Alogliptin)
19%
19% vs. Nesina (Alogliptin)
Side effects
NesinaGlucotrol

We haven’t found good data for Nesina side effects.

FDA side effect reports for Nesina »
  • Passing gas 2%
  • Dizziness 1%
  • Nervousness 1%
More Glucotrol side effects »
How it works
NesinaGlucotrol
alogliptin is an anti-diabetic drug. It improves your body's ability to use insulin to lower your blood sugar.Glucotrol (Glipizide) is an anti-diabetic drug. It stimulates your body to make more insulin to lower blood sugar.
Type of medication
NesinaGlucotrol
Coming soon.
Anti-diabetic
Sulfonylurea
Prescription only
Available as
NesinaGlucotrol
  • Pill
  • Pill
  • Extended release
Used for (click to learn more)
NesinaGlucotrol
  • Diabetes mellitus type 2
Risk factors for serious side effects
NesinaGlucotrol
      Detailed Nesina (Alogliptin) risks & warnings »
        • Use of other blood sugar lowering medicines
        • Alcohol
        • Intense physical activity
        • History of sulfa allergies
        Detailed Glucotrol (Glipizide) risks & warnings »
        Pregnancy category
        NesinaGlucotrol
        BFDA pregnancy category (Probably safe)

        Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

        See the FDA package insert
        CFDA pregnancy category (Weigh risks vs. benefits)

        Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

        See the FDA package insert
        Alcohol
        No specific alcohol-related info.
        • Avoid drinking alcohol.
        Food
        No specific food-related info.
        • Food can cause unpredictable effects of the immediate-release version of Glipizide, so you have to take it at least 30 minutes before a meal.
        • Works best if you take it 30 minutes before a meal, usually your first big meal of the day.
        • Eat regular, balanced meals to avoid low blood sugar.
        Kidneys and liver
        No specific kidneys and liver-related info.
        • Might be a better choice for people with kidney problems compared to similar drugs because Glipizide isn't processed by the kidneys.
        Sex
        No specific sex-related info.No specific sex-related info.
        Sleep
        No specific sleep-related info.No specific sleep-related info.
        Weight
        No specific weight-related info.
        • Can cause mild weight gain (2 to 3 pounds).
        • Can cause weight gain, dizziness, or stomach upset.
        Upsides and benefits
        NesinaGlucotrol
        • Lowers A1c levels by around 1%. (Hemoglobin A1c measures your average blood sugar over time.)
        • Rarely causes low blood sugar.
        • Patients taking alogliptin had less cold symptoms than patients taking Januvia.
        • Oral blood sugar-lowering medicine.
        • Prevents the harmful effects of high sugar levels on your organs and blood vessels.
        • Lowers A1c levels by 1-2%. (Hemoglobin A1c measures your average blood sugar over time.)
        • Might be a better choice for people with kidney problems compared to similar drugs because Glipizide isn't processed by the kidneys.
        • One of the least expensive diabetes medicines.
        • Oral blood sugar-lowering medicine.
        • Prevents the harmful effects of high sugar levels on your organs and blood vessels.
        Downsides and risks
        NesinaGlucotrol
        • Not as strong as other diabetes medicines. Your doctor might add it to your blood sugar-lowering regimen if your sugar levels are still too high.
        • Likely expensive since there's no generic version available.
        • Some people might get frequent throat infections or nasal congestion.
        • Higher risk of low blood sugar episodes than other kinds of oral diabetes medicines.
        • You have to check your blood sugar 2 to 5 times a week (less often once you are on a stable dose).
        • Can cause mild weight gain (2 to 3 pounds).
        • Loses effectiveness over time or as your body stops making insulin.
        • Food can cause unpredictable effects of the immediate-release version of Glipizide, so you have to take it at least 30 minutes before a meal.
        Tips from our pharmacists for people taking the medication
        NesinaGlucotrol
        • Can cause headache and cold-like symptoms.
        • Tell your doctor about any mental confusion, persistent abdominal pain, dark urine, yellowing of eyes/skin, or easy bruising.
        • Can be expensive depending on insurance coverage.
        • Check your blood sugar regularly.
        • Works best if you take it 30 minutes before a meal, usually your first big meal of the day.
        • Can cause weight gain, dizziness, or stomach upset.
        • Avoid drinking alcohol.
        • Eat regular, balanced meals to avoid low blood sugar.
        • Check your blood sugar regularly.
        Learn more
        More about NesinaSide effectsReviews & ratingsAlternativesFDA package insert
        More about GlucotrolSide effectsReviews & ratingsAlternativesFDA package insert