Compare Nesina vs. Glucotrol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Nesina
(Alogliptin)

Glucotrol
(Glipizide)

Lowers your blood sugar. alogliptin is a good add-on treatment if your blood sugar is still too high, but you don't want to use an injectable medicine.Lowers blood sugar. Glucotrol (Glipizide) is a very effective oral blood sugar-lowering medicine. It can cause low blood sugar, so make sure you know what the symptoms are and always have a source of sugar nearby.
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Reviews & ratings
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Have you used Nesina (Alogliptin)?
Worth itNot sureNot worth it
Reviews for Glucotrol (Glipizide)
50%
-50% worse vs. Nesina (Alogliptin)
32%
-68% worse vs. Nesina (Alogliptin)
19%
-19% worse vs. Nesina (Alogliptin)
332 reviews
Have you used Glucotrol (Glipizide)?
Worth itNot sureNot worth it
Side effects
NesinaGlucotrol

We haven’t found good data for Nesina side effects.

FDA side effect reports for Nesina »
  • Dizziness 1%
  • Diarrhea 5%
  • Nervousness 1%
  • Tremor 4%
  • Passing gas 2%
  • Drowsiness 2%
More Glucotrol side effects »
How it works
NesinaGlucotrol
alogliptin is an anti-diabetic drug. It improves your body's ability to use insulin to lower your blood sugar.Glucotrol (Glipizide) is an anti-diabetic drug. It stimulates your body to make more insulin to lower blood sugar.
Type of medication
NesinaGlucotrol
Prescription only
Available as
NesinaGlucotrol
  • Pill
  • Pill
  • Extended release
Used for
NesinaGlucotrol
  • Diabetes Mellitus Type 2
Risk factors for serious side effects
NesinaGlucotrol
      Detailed Nesina (Alogliptin) risks & warnings »
        • Use of other blood sugar lowering medicines
        • Alcohol
        • Intense physical activity
        • History of sulfa allergies
        Detailed Glucotrol (Glipizide) risks & warnings »
        Pregnancy

        Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

        Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

        Alcohol
        NesinaGlucotrol
        No alcohol related info.
        • Avoid drinking alcohol.
        Food
        NesinaGlucotrol
        No food related info.
        • Food can cause unpredictable effects of the immediate-release version of Glipizide, so you have to take it at least 30 minutes before a meal.
        • Eat regular, balanced meals to avoid low blood sugar.
        Kidneys and liver
        NesinaGlucotrol
        No kidneys and liver related info.
        • Might be a better choice for people with kidney problems compared to similar drugs because Glipizide isn't processed by the kidneys.
        Weight
        NesinaGlucotrol
        No weight related info.
        • Can cause mild weight gain (2 to 3 pounds).
        • Can cause weight gain, dizziness, or stomach upset.
        Upsides and benefits
        NesinaGlucotrol
        • Oral blood sugar-lowering medicine.
        • Lowers A1c levels by around 1%. (Hemoglobin A1c measures your average blood sugar over time.)
        • Prevents the harmful effects of high sugar levels on your organs and blood vessels.
        • Rarely causes low blood sugar.
        • Patients taking alogliptin had less cold symptoms than patients taking Januvia.
        • Oral blood sugar-lowering medicine.
        • Lowers A1c levels by 1-2%. (Hemoglobin A1c measures your average blood sugar over time.)
        • Prevents the harmful effects of high sugar levels on your organs and blood vessels.
        • Might be a better choice for people with kidney problems compared to similar drugs because Glipizide isn't processed by the kidneys.
        • One of the least expensive diabetes medicines.
        Downsides and risks
        NesinaGlucotrol
        • Not as strong as other diabetes medicines. Your doctor might add it to your blood sugar-lowering regimen if your sugar levels are still too high.
        • Likely expensive since there's no generic version available.
        • Some people might get frequent throat infections or nasal congestion.
        • Higher risk of low blood sugar episodes than other kinds of oral diabetes medicines.
        • You have to check your blood sugar 2 to 5 times a week (less often once you are on a stable dose).
        • Can cause mild weight gain (2 to 3 pounds).
        • Loses effectiveness over time or as your body stops making insulin.
        • Food can cause unpredictable effects of the immediate-release version of Glipizide, so you have to take it at least 30 minutes before a meal.
        Tips from our pharmacists for people taking the medication
        NesinaGlucotrol
        • Can cause headache and cold-like symptoms.
        • Tell your doctor about any mental confusion, persistent abdominal pain, dark urine, yellowing of eyes/skin, or easy bruising.
        • Can be expensive depending on insurance coverage.
        • Check your blood sugar regularly.
        • Works best if you take it 30 minutes before a meal, usually your first big meal of the day.
        • Can cause weight gain, dizziness, or stomach upset.
        • Avoid drinking alcohol.
        • Eat regular, balanced meals to avoid low blood sugar.
        • Check your blood sugar regularly.
        Learn more
        More about NesinaSide effectsReviews & ratingsAlternativesFDA package insert
        Have you used Nesina (Alogliptin)?
        Worth itNot sureNot worth it
        More about GlucotrolSide effectsReviews & ratingsAlternativesFDA package insert
        Have you used Glucotrol (Glipizide)?
        Worth itNot sureNot worth it