Compare Nesina vs. Glucotrol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Nesina
(alogliptin)

Glucotrol
(glipizide)

Lowers your blood sugar. alogliptin is a good add-on treatment if your blood sugar is still too high, but you don't want to use an injectable medicine.Lowers blood sugar. Glucotrol (glipizide) is an effective medicine for lowering blood sugar, but it can cause your blood sugar level to be too low so you must always carry some form of sugar with you that can be readily used.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Nesina (alogliptin)?
Worth itNot sureNot worth it
Reviews for Glucotrol
50%
+50% better vs. Nesina
32%
+68% better vs. Nesina
19%
+19% better vs. Nesina
332 reviews
Have you used Glucotrol (glipizide)?
Worth itNot sureNot worth it
Side effects
NesinaGlucotrol

We haven’t found good data for Nesina side effects.

FDA side effect reports for Nesina »
  • Dizziness 1%
  • Diarrhea 5%
  • Nervousness 1%
  • Tremor 4%
  • Passing gas 2%
  • Low blood sugar 3%
  • Constipation 3%
  • Nausea 3%
  • Headache 2%
More Glucotrol side effects »
How it works
NesinaGlucotrol
alogliptin is an anti-diabetic drug. It improves your body's ability to use insulin to lower your blood sugar.Glucotrol (glipizide) stimulates your body to release insulin and lower blood sugar.
Type of medication
NesinaGlucotrol
Prescription only
Available as
NesinaGlucotrol
  • Pill
  • Pill
  • Extended release pill
Used for
NesinaGlucotrol
  • Diabetes Mellitus Type 2
Risk factors for serious side effects
NesinaGlucotrol
    Detailed Nesina (alogliptin) risks & warnings »
    • Skipping meals or having inconsistent meal times
    • Drinking alcohol
    • Using other blood sugar-lowering medicine
    • People age 60 or older
    • Those with kidney and/or liver problems
    Detailed Glucotrol (glipizide) risks & warnings »
    Pregnancy

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Alcohol
    NesinaGlucotrol
    No alcohol related info.
    • Avoid drinking alcohol while taking Glucotrol (glipizide).
    Food
    NesinaGlucotrol
    No food related info.
    • Eat regular and well-balanced meals to keep your blood sugar levels normal.
    Weight
    NesinaGlucotrol
    No weight related info.
    • Can cause mild weight gain of 2-3lb.
    Upsides and benefits
    NesinaGlucotrol
    • Oral blood sugar-lowering medicine.
    • Lowers A1c levels by around 1%. (Hemoglobin A1c measures your average blood sugar over time.)
    • Prevents the harmful effects of high sugar levels on your organs and blood vessels.
    • Rarely causes low blood sugar.
    • Patients taking alogliptin had less cold symptoms than patients taking Januvia.
    • Lowers A1c levels by 1-2%.
    • Glucotrol (glipizide) is an oral medicine so it might be a good alternative for those who don't like injections.
    • Protects your organs and blood vessels by preventing the harmful effects of high blood sugar levels.
    • Okay to use by people with kidney problems.
    • Available as a generic form and is relatively cheap.
    Downsides and risks
    NesinaGlucotrol
    • Not as strong as other diabetes medicines. Your doctor might add it to your blood sugar-lowering regimen if your sugar levels are still too high.
    • Likely expensive since there's no generic version available.
    • Some people might get frequent throat infections or nasal congestion.
    • Has a higher risk than other diabetes medicine for causing blood sugar levels to be too low.
    • While taking Glucotrol (glipizide), your blood sugars should be checked 2 to 5 times a week, but less often once you are on a stable dose.
    • Can cause mild weight gain of 2-3lb.
    • Might lose its effectiveness over time.
    • Needs to be taken 30 minutes before a meal for it to be most effective.
    Tips from our pharmacists for people taking the medication
    NesinaGlucotrol
    • Can cause headache and cold-like symptoms.
    • Tell your doctor about any mental confusion, persistent abdominal pain, dark urine, yellowing of eyes/skin, or easy bruising.
    • Can be expensive depending on insurance coverage.
    • Check your blood sugar regularly.
    • Take the medicine 30 minutes before eating, usually before your first big meal of the day.
    • Avoid drinking alcohol while taking Glucotrol (glipizide).
    • Eat regular and well-balanced meals to keep your blood sugar levels normal.
    • Check your blood sugar regularly.
    • Glucotrol (glipizide) can cause dizziness so avoid activities that require coordination until you know how your body can handle the medicine.
    Learn more
    More about NesinaSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Nesina (alogliptin)?
    Worth itNot sureNot worth it
    More about GlucotrolSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Glucotrol (glipizide)?
    Worth itNot sureNot worth it