Compare Nesina vs. glyburide

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Nesina (Alogliptin)

Diabeta (glyburide)

Prescription only
Lowers your blood sugar.

alogliptin is a good add-on treatment if your blood sugar is still too high, but you don't want to use an injectable medicine.

Lowers blood sugar.

Diabeta (glyburide) is a good oral anti-diabetic medicine, but can cause hypoglycemia or low blood sugar.

4.4/ 7 average rating with 110 reviewsforglyburide
Upsides
  • Oral blood sugar-lowering medicine.
  • Lowers A1c levels by around 1%. (Hemoglobin A1c measures your average blood sugar over time.)
  • Prevents the harmful effects of high sugar levels on your organs and blood vessels.
  • Rarely causes low blood sugar.
  • Patients taking alogliptin had less cold symptoms than patients taking Januvia.
  • Available as an oral tablet.
  • Lowers your A1c (average blood sugar over time) up to 2%.
  • Available in generic version.
  • Available in single pill combination with other anti-diabetic medicines.
Downsides
  • Not as strong as other diabetes medicines. Your doctor might add it to your blood sugar-lowering regimen if your sugar levels are still too high.
  • Likely expensive since there's no generic version available.
  • Some people might get frequent throat infections or nasal congestion.
  • More likely to cause hypoglycemia or low blood sugar than other types of oral anti-diabetics.
  • You will have to check your blood sugar often when you first start taking it.
  • Can cause weight gain (about 2 to 3 pounds).
  • Not ideal for elderly or those with poor kidney function.
  • May not work as well for those with severe diabetes and when pancreas cannot produce insulin.
Used for
  • Diabetes mellitus type 2
Dosage forms
  • Pill
  • Pill
Price
Lowest price near you
$94.57
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Lowest price near you
$10
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Reviews
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110 
45%
think this treatment is worth it
34%
think this treatment works well
21%
think this treatment is a hassle

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Side effects
The Nesina (Alogliptin) FDA package insert doesn’t have numbers about how common side effects are.
The Diabeta (glyburide) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
See more detailed risks and warnings
  • Low blood sugar

    Over age 65

    ...and 4 more risk factors

  • Severe allergic reactions

    History of sulfa allergies

See more detailed risks and warnings